Chorea clinical trials
The registry lists 42 studies for Chorea across more than 10 countries. 9 are recruiting or about to start. 7 of them are mainly about Chorea (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29. Counting its narrower condition Huntington Disease too: 312 studies, 61 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Boston Children's Hospital (4) · Hoffmann-La Roche (3) · National Institute of Neurological Disorders and Stroke (NINDS) (3) · Neurocrine Biosciences (2) · University of Iowa (2) · Pfizer (2) · SOM Innovation Biotech SA (2) · Siena Biotech S.p.A. (2)
What is being tested here
Drugs under test in Chorea studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2, phase 3 first
- May 2027Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's Disease · Phase 3 · Skyhawk Therapeutics, Inc.
- May 2027TREAT-SC: Early, Short Course Oral Dexamethasone for the Treatment of Sydenham Chorea in Children · Phase 3 · Starship Child Health, Te Toka Tumai Auckland
Who these studies take
Of the 7 Chorea studies recruiting now, 1 (14%) set no upper age limit and 6 (86%) stop at 75 or younger. 5 (71%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (71%) | 5 (71%) |
| 18 | 5 (71%) | 5 (71%) |
| 30 | 4 (57%) | 4 (57%) |
| 40 | 3 (43%) | 3 (43%) |
| 50 | 3 (43%) | 3 (43%) |
| 65 | 3 (43%) | 3 (43%) |
| 75 | 2 (29%) | 2 (29%) |
| 85 | 1 (14%) | 1 (14%) |
Across all 42 studies, recruiting or not: 50% stop at 75 or younger and 36% at 65; 43% take children; 0% are for women only and 0% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 42 of 42. search them.
- Neural Correlates of Movement Disorders Associated With PRRT2 Related Paroxysmal Kinesigenic Dyskinesia - an Ancillary Study of AMEDYST ResearchRecruitingNCT06701851Not applicable1 country
- A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's DiseaseRecruitingNCT06826612Phase 1/21 country
- Deep Brain Stimulation (DBS) MatchMakerEnrolling by invitationNCT069128411 country
- A Multicenter Pediatric Deep Brain Stimulation RegistryRecruitingNCT065856181 country
- A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia SyndromesRecruitingNCT065856051 country
- Registry and Natural History of Epilepsy-Dyskinesia SyndromesRecruitingNCT069677271 country
- TREAT-SC: Early, Short Course Oral Dexamethasone for the Treatment of Sydenham Chorea in ChildrenRecruitingNCT06259006Phase 32 countries
- Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers StudyRecruitingNCT062731502 countries
- European Registry on Rare Neurological DiseasesNot yet recruitingNCT04319796
- Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersCompletedNCT000012461 country
- Real World Effectiveness and Safety of Deutetrabenazine in Adult Chinese Participants With Huntington's Disease (HD) Chorea in ChinaCompletedNCT07601516Phase 41 country
- Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's DiseaseActive, not recruitingNCT06873334Phase 2/32 countries
- Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral PalsyCompletedNCT05206513Phase 310 countries
- Stimulation of the Dentate Nucleus of the Cerebellum for the Treatment of Refractory Spasticity With or Without DystoniaCompletedNCT07231302
- Efficacy and Safety on SOM3355 in Huntington's Disease ChoreaCompletedNCT05475483Phase 27 countries
- Risperidone for the Treatment of Huntington's Disease Involuntary MovementsCompletedNCT04201834Phase 21 country
- A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's DiseaseCompletedNCT04000594Phase 12 countries
- A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's DiseaseCompletedNCT03761849Phase 318 countries
- Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington DiseaseCompletedNCT04102579Phase 32 countries
- Compassionate Use of Tetrabenazine in the Treatment of Abnormal MovementsNo longer availableNCT00642057
- Deep Brain Stimulation Treatment for Chorea in Huntington's DiseaseStatus unknownNCT04244513Not applicable1 country
- Deep Brain Stimulation (DBS) of the Globus Pallidus (GP) in Huntington's Disease (HD)CompletedNCT02535884Not applicable4 countries
- Alternatives for Reducing Chorea in Huntington DiseaseCompletedNCT01897896Phase 33 countries
- Efficacy and Safety of SOM3355 in Huntington's Disease ChoreaCompletedNCT03575676Phase 21 country
- Dopaminergic Receptors in Sydenham's ChoreaStatus unknownNCT040849771 country
- Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021TerminatedNCT02342548Phase 25 countries
- Impact of Xenazine(Tetrabenazine)on Gait and Functional Activity in Individuals With Huntington's DiseaseCompletedNCT014514631 country
- Randomized, Placebo Controlled Study Of The Efficacy And Safety Of PF-02545920 In Subjects With Huntington's DiseaseCompletedNCT02197130Phase 25 countries
- First Time Use of SD-809 in Huntington DiseaseCompletedNCT01795859Phase 33 countries
- Neurophysiological Studies in Patients With Paroxysmal Hyperkinetic Movement DisordersCompletedNCT000568881 country
- An Exploratory Clinical Trial in Early Stage Huntington's Disease Patients With SEN0014196CompletedNCT01485952Phase 11 country
- Intravenous Immunoglobulins as Effective Treatment in Sydenham's ChoreaCompletedNCT00615797Not applicable1 country
- A Open-label Food Effect Study With SEN0014196 in Subjects With Huntington DiseaseCompletedNCT01485965Phase 11 country
- Citalopram to Enhance Cognition in HDCompletedNCT00271596Phase 21 country
- Atomoxetine and Huntington's DiseaseCompletedNCT00368849Phase 21 country
- Efficacy, Safety and Tolerability of AFQ056 in Patients With Huntington's Disease in Reducing ChoreaTerminatedNCT01019473Phase 22 countries
- Amantadine for Improving Neurologic Symptoms in Ataxia-TelangiectasiaCompletedNCT00950196Phase 41 country
- Ursodiol in Huntington's DiseaseStatus unknownNCT00514774Phase 11 country
- Far Infrared Irradiation for Managing, Control and Treatment of Huntington's Disease (HD)Status unknownNCT00675077Phase 11 country
- Treatment of Huntington's Chorea With AmantadineCompletedNCT00001930Phase 21 country
- Heart and Skeletal Muscle Problems in NeuroacanthocytosisCompletedNCT000072281 country
- Single Photon Emission Computed Tomography (SPECT) to Study Paroxysmal Hyperkinetic Movement DisordersCompletedNCT000513371 country