Tominersen clinical trials
Also written RO7234292;.
How each study uses tominersen is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
5 studies that test it; most in 2019 (3)
| Year | Studies |
|---|---|
| 2018 | 1 |
| 2019 | 3 |
| 2023 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 5 · Other 0
Studies
Open first, then newest update. How each study uses tominersen is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 5
- GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's DiseaseActive, not recruitingPhase 2Hoffmann-La RocheNCT05686551Written as Tominersen
- A Study to Investigate the Pharmacokinetics and Pharmacodynamics of RO7234292 (RG6042) in CSF and Plasma, and Safety and Tolerability Following Intrathecal Administration in Patients With Huntington's DiseaseCompletedPhase 1Hoffmann-La RocheNCT04000594Written as RO7234292 (RG6042)
- A Study to Evaluate the Efficacy and Safety of Intrathecally Administered RO7234292 (RG6042) in Participants With Manifest Huntington's DiseaseCompletedPhase 3Hoffmann-La RocheNCT03761849Written as RO7234292
- An Open-Label Extension Study to Evaluate Long-Term Safety and Tolerability of RO7234292 (RG6042) in Huntington's Disease Participants Who Participated in Prior Roche and Genentech Sponsored StudiesCompletedPhase 3Hoffmann-La RocheNCT03842969Written as RO7234292 (RG6042)
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7234292 (ISIS 443139) in Huntington's Disease Patients Who Participated in Prior Investigational Studies of RO7234292 (ISIS 443139)CompletedPhase 2Hoffmann-La RocheNCT03342053Written as RO7234292 (RG6042)
Codes
What other systems call tominersen · ClinicalTrials.gg INT001680
- MeSH (NLM) C000718631tominersenOne source NLM
- UNII (FDA) 7QI41X9QWCTOMINERSENConfirmed FDA, NLM
- NCI Thesaurus C171741TominersenOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000718631 | tominersen | One source NLM |
| UNII (FDA) | 7QI41X9QWC | TOMINERSEN | Confirmed FDA, NLM |
| NCI Thesaurus | C171741 | Tominersen | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.