Bone Marrow Diseases clinical trials
The registry lists 66 studies for Bone Marrow Diseases across more than 10 countries. 12 are recruiting or about to start. 10 of them are mainly about Bone Marrow Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 28 narrower conditions too, such as Myelodysplastic Syndromes: 4,389 studies, 787 open.
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Who runs them
Novartis Pharmaceuticals (7) · National Heart, Lung, and Blood Institute (NHLBI) (4) · Groupe Francophone des Myelodysplasies (3) · Ariad Pharmaceuticals (3) · Cellenkos, Inc. (2) · AOP Orphan Pharmaceuticals AG (2) · Shandong University (2) · Center for International Blood and Marrow Transplant Research (2)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis · Center for International Blood and Marrow Transplant Research
- Apr 2027Leading in MPNs Beyond Ruxolitinib in Combo With T-Regs · Cellenkos, Inc.
- May 2027A Clinical Trial of CK0801 (a New Drug) in Patients With Bone Marrow Failure Syndrome (BMF) · Cellenkos, Inc.
- Oct 2027Myeloproliferative Neoplasms (MPNs) Patient Registry · University Health Network, Toronto
- Nov 2027Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome · Orca Biosystems, Inc.
Who these studies take
Of the 8 Bone Marrow Diseases studies recruiting now, 6 (75%) set no upper age limit and 0 (0%) stop at 75 or younger. 3 (38%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (25%) | 2 (25%) |
| 18 | 8 (100%) | 8 (100%) |
| 30 | 8 (100%) | 8 (100%) |
| 40 | 8 (100%) | 8 (100%) |
| 50 | 8 (100%) | 8 (100%) |
| 65 | 8 (100%) | 8 (100%) |
| 75 | 8 (100%) | 8 (100%) |
| 85 | 8 (100%) | 8 (100%) |
Across all 66 studies, recruiting or not: 14% stop at 75 or younger and 8% at 65; 20% take children; 2% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Phase 2 Study of Oral Epetraborole in Adults With Polycythemia VeraOct 23, 2026NCT07891533
Studies
Recruiting first, then most recently updated. Showing 50 of 66. Browse all 66 → or search them.
- Pacritinib, a Kinase Inhibitor of CSF1R, IRAK1, JAK2, and FLT3, in Adults and Pediatric Participants 12 Years of Age or Older With Myelodysplastic Syndromes or Myelodysplastic/Myeloproliferative NeoplasmsRecruitingNCT06303193Phase 1/21 country
- Phase 2 Study of Oral Epetraborole in Adults With Polycythemia VeraNot yet recruitingNCT07891533Phase 21 country
- Leading in MPNs Beyond Ruxolitinib in Combo With T-RegsRecruitingNCT05423691Phase 11 country
- Therapeutic RSK1 Targeting in Myeloid MalignanciesRecruitingNCT07379125Phase 11 country
- Molecular and Clinical Analysis of Bone Marrow Failure: A Secondary Research StudyEnrolling by invitationNCT071028491 country
- OSTEOMICS: Identifying Regulators of Bone HomeostasisRecruitingNCT057328701 country
- Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromeRecruitingNCT07216443Phase 21 country
- Role of Diffusion MRI in Differentiation of Various Bone Marrow LesionsNot yet recruitingNCT06703138
- Study of VIP943 in Subjects With Advanced CD123+ Hematologic MalignanciesRecruitingNCT06034275Phase 11 country
- A Study of HS-20106 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic SyndromesNot yet recruitingNCT06594965Phase 21 country
- Myeloproliferative Neoplasms (MPNs) Patient RegistryRecruitingNCT027602381 country
- The International PNH Interest Group PNH RegistryRecruitingNCT065247261 country
- A Clinical Trial of CK0801 (a New Drug) in Patients With Bone Marrow Failure Syndrome (BMF)Active, not recruitingNCT03773393Phase 11 country
- A Study to Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in IndiaActive, not recruitingNCT05891249Phase 41 country
- HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD ProphylaxisActive, not recruitingNCT06001385Phase 21 country
- Pacritinib With Aza for Upfront Myelodysplastic SyndromeWithdrawnNCT07387354Phase 1/2
- A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative MalignanciesCompletedNCT02158858Phase 1/29 countries
- A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia MyelofibrosisActive, not recruitingNCT03165734Phase 324 countries
- HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation CyclophosphamideActive, not recruitingNCT04904588Phase 21 country
- Ponatinib in Participants With Resistant Chronic Phase Chronic Myeloid Leukemia (CP-CML) to Characterize the Efficacy and Safety of a Range of DosesCompletedNCT02467270Phase 221 countries
- Ibrutinib and PD-1 Blockade in High Risk Lymphocytic LeukemiaTerminatedNCT03514017Phase 21 country
- Impact of Physical and Occupational Therapy in New BMT PatientsCompletedNCT059785831 country
- Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDSCompletedNCT03066648Phase 18 countries
- Bortezomib and Low Dose Cytarabine in the Treatment of High-risk Myelodysplastic SyndromesCompletedNCT00411905Phase 1/21 country
- Tube Feeding in Children Having a Bone Marrow TransplantCompletedNCT048046311 country
- A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)CompletedNCT04173494Phase 322 countries
- The Effect of Music Therapy on Comfort, Pain and AnxietyCompletedNCT05895357Not applicable1 country
- Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple MyelomaCompletedNCT01345019Phase 329 countries
- Bone Marrow Adiposity and Fragility Fractures in Postmenopausal WomenCompletedNCT032191251 country
- A Study of Ponatinib in Japanese Participants With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia (ALL)CompletedNCT01667133Phase 1/21 country
- Sertraline in Treatment of Low-Risk Myelodysplastic SyndromeTerminatedNCT02452983Phase 11 country
- Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MFCompletedNCT01423851Phase 1/21 country
- A Study Comparing Ponatinib and Nilotinib in Participants With Chronic Myeloid LeukemiaTerminatedNCT02627677Phase 31 country
- Pacritinib Versus Best Available Therapy to Treat Patients With Myelofibrosis and ThrombocytopeniaTerminatedNCT02055781Phase 312 countries
- Efficacy and Safety of Elizaria® vs. Soliris® in Patients With PNHCompletedNCT04463056Phase 31 country
- Ruxolitinib Efficacy and Safety in Patients With HU Resistant or Intolerant Polycythemia Vera vs Best Available Therapy.CompletedNCT02038036Phase 312 countries
- AOP2014 vs. BAT in Patients With Polycythemia Vera Who Previously Participated in the PROUD-PV Study.CompletedNCT02218047Phase 312 countries
- Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell TransplantNo longer availableNCT012000171 country
- A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT02130557Phase 326 countries
- Busulfan Concentration in Saliva and Plasma, and Its Relationship With Salivary Changes and Mucositis in the Digestive Tract of Patients Submitted to Hematopoietic Stem Cell TransplantationCompletedNCT03492749
- Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL)CompletedNCT022521592 countries
- Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.CompletedNCT01844765Phase 213 countries
- A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)CompletedNCT00471497Phase 335 countries
- Collection of Blood and Bone Marrow From Healthy Volunteers and Patients for Research PurposesCompletedNCT000016271 country
- Pacritinib Versus Best Available Therapy to Treat MyelofibrosisTerminatedNCT01773187Phase 312 countries
- Cytokine Gene Polymorphisms in Bone Marrow FailureCompletedNCT000856701 country
- Efficacy and Safety of Simtuzumab in Adults With Primary, Post Polycythemia Vera or Post Essential Thrombocythemia MyelofibrosisCompletedNCT01369498Phase 21 country
- Safety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential ThrombocythemiaTerminatedNCT01998828Phase 25 countries
- A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MFCompletedNCT01787552Phase 1/211 countries
- Clofarabine Followed By Lenalidomide for High-Risk Myelodysplastic Syndromes and Acute Myeloid LeukemiaCompletedNCT01629082Phase 11 country