An observational study in Fractures, Bone, Bone Marrow Disease and Fat Disorder, sponsored by University Hospital, Lille. Completed at 1 site in France. Open to female participants aged 50 Years to 90 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-11-04.
Sponsored by University Hospital, Lille · Observational
The purpose is to determine in a case-control study if an association exist between bone marrow adiposity and fragility fractures in post-menopausal women.
200 studies on the registry are indexed under Bone Marrow Diseases; 34 are open to participants now.
This study's enrollment of 203 is above the median of 80 across 59 observational studies indexed under Bone Marrow Diseases.
Browse Bone Marrow Diseases studies →University Hospital, Lille is the lead sponsor of 625 studies on the registry; 141 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Post-menopausal women
Exclusion Criteria:
occurence of incident major osteoporotic fracture less than 12 weeks
Device: Dixon Magnetic Resonance Imaging
no history of fragility fracture
Device: dual-energy X-ray absorptiometry (DXA)
MRI of the lumbar spine (L1 to L4) and hip (non-dominant) for the measurement of Ad Med. (In%) by the DIXON sequence.
Subjects will undergo DXA scan to assess total body (less head) and lumbar spine bone mineral density.
Bone marrow fat content at lumbar spine
Total bone marrow fat content (percentage) at lumbar spine (L1-L4) measured with magnetic resonance imaging
Time frame: 24 months
Bone marrow fat content at total hip
Total bone marrow fat content (percentage) at total hip measured with magnetic resonance imaging
Time frame: 24 months
Bone mineral density at lumbar spine
Bone mineral density (g/cm2) at lumbar spine (L1-L4) measured by DXA
Time frame: 24 months
Bone mineral density at total hip
Bone mineral density (g/cm2) at total hip measured by DXA
Time frame: 24 months
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.
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University Hospital, Lille