Azoospermia, Nonobstructive clinical trials

The registry lists 23 studies for Azoospermia, Nonobstructive across more than 10 countries. 7 are recruiting or about to start. 17 of them are mainly about Azoospermia, Nonobstructive (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.

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Status

Completed: 10
Recruiting: 6
Status unknown: 3
Active, not recruiting: 2
Enrolling by invitation: 1
Withdrawn: 1

Phase

Phase 2: 3
Phase 3: 2
Phase 1: 2

Where

United States: 4
Egypt: 3
China: 3
Turkey: 3
Italy: 2
Denmark: 2

Who runs them

Assiut University (2) · Acibadem University (1) · Clinique Ovo (1) · IRCCS San Raffaele (1) · A.O.U. Città della Salute e della Scienza (1) · Duzce University (1) · Herlev and Gentofte Hospital (1) · Hospices Civils de Lyon (1)

What is being tested here

Drugs under test in Azoospermia, Nonobstructive studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Isotretinoin	1	0	1
Platelet rich plasma	1	0	1
Letrozole	0	1	1
Clomiphene	0	1	1

Coming up

0phase 3 studies under way

3studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3

Dec 2026Platelet Rich Plasma Testis Treatment for Infertile Men · Stanford University
Apr 2027Maternal Inheritance of a Pathogenic MT-ND1 Mutation Causes Mitochondrial Dysfunction and Spermatogenic Failure in Men · The Third Affiliated Hospital of Guangzhou Medical University
Jun 2027Isotretinoin vs hCG for Male Infertility Due to Low or Absent Sperm · University of Nebraska

Who these studies take

Of the 6 Azoospermia, Nonobstructive studies recruiting now, 2 (33%) set no upper age limit and 2 (33%) stop at 75 or younger. 1 (17%) take children under 18. 0 (0%) are for women only and 4 (67%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 6
Age	Women	Men
10	1 (17%)	1 (17%)
18	2 (33%)	5 (83%)
30	2 (33%)	6 (100%)
40	2 (33%)	6 (100%)
50	2 (33%)	6 (100%)
65	2 (33%)	5 (83%)
75	2 (33%)	5 (83%)
85	2 (33%)	4 (67%)

Across all 23 studies, recruiting or not: 57% stop at 75 or younger and 48% at 65; 9% take children; 0% are for women only and 87% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered1

Evaluation of Assisted Reproductive Technology (ART) Outcomes in Couples With Nonobstructive Azoospermia, Cryptozoospermia, and Severe OligozoospermiaOct 27, 2026NCT07897279

Studies

Recruiting first, then most recently updated. Showing 23 of 23. search them.