An interventional study of micro-dissection testicular sperm extraction in Male Infertility and Azoospermia, Nonobstructive, sponsored by South Valley University. Completed at 1 site in Egypt. Open to male participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-05-25.
Sponsored by South Valley University · Not applicable, Interventional, and Supportive care
this study predicts the factors of successful micro testicular sperm extraction in azoospermia patients in male infertility
primary outcomes: these factors were the age, testicular size, hormonal, evidence of varicocles and the out come of Micro_TESE secondary outcomes: make good decision for Micro-TESE with low economic laboratory and radiology requirement As every failed microTESE-ICSI procedure exposes the couple to an emotional, financial burden and increase the incidence of complication such as bleeding, hematoma and testicular atrophy
23 studies on the registry are indexed under Azoospermia, Nonobstructive; 7 are open to participants now.
This study's enrollment of 300 is above the median of 61 across 12 interventional studies indexed under Azoospermia, Nonobstructive.
Browse Azoospermia, Nonobstructive studies →South Valley University is the lead sponsor of 153 studies on the registry; 46 are open to participants now.
Compared within Azoospermia, Nonobstructive, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Infertility, Male. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Inclusion Criteria: Non obstructive Azoospermia with no genetic abnormalties as klinefelter syndrome
Exclusion Criteria:
azoospermia non obstructive type
Procedure: micro-dissection testicular sperm extraction
dissection of the seminefrous tubules under microscope to extract sperms
Also known as: TESE, TESA, PESA
Sperm Retrieval Success Rate and identification of Predictive Factors
Determine which preoperative factors are significantly associated with successful sperm retrieval. These may include: Serum Follicle-Stimulating Hormone (FSH) Levels: Elevated FSH levels have been linked to reduced sperm retrieval success. And patient Age and testicular size to reach the best one to predict the success rate
Time frame: 1st 1 year
Assess the success rates of ART procedures following sperm retrieval and complications
Assisted Reproductive Technology (ART) Outcomes Fertilization Rates: The percentage of oocytes successfully fertilized. Embryo Development: Quality and progression of embryos to the blastocyst stage. Clinical Pregnancy Rates: Confirmed pregnancies via ultrasound. Live Birth Rates: The ultimate success metric of ART procedures Complication Rates Monitor and document any complications arising from the sperm retrieval procedure, such as: Testicular Hematoma Infection Testicular Atrophy
Time frame: 2 years
Plan to share: Yes — according to the results
Supporting information: Study protocol
Time frame: 2 years
Access criteria: urologist and andrologist
Data sharing details ↗ · svuijm.journals.ekb.eg
Ran from Jun 2022 to primary completion in Apr 2024, 22 months.
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