Adrenal Gland Neoplasms clinical trials
The registry lists 62 studies for Adrenal Gland Neoplasms across more than 10 countries. 19 are recruiting or about to start. 22 of them are mainly about Adrenal Gland Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 4 narrower conditions too, such as Adrenocortical Carcinoma: 202 studies, 59 open.
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Status
Who runs them
National Cancer Institute (NCI) (5) · University of Wuerzburg (4) · The Affiliated Hospital of Qingdao University (3) · Instituto do Cancer do Estado de São Paulo (2) · Jonsson Comprehensive Cancer Center (2) · University of Roma La Sapienza (2) · Wuerzburg University Hospital (2) · M.D. Anderson Cancer Center (2)
What is being tested here
Drugs under test in Adrenal Gland Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Immunocytokine NHS-IL12 | 1 | 0 | 1 |
| Olaparib | 1 | 0 | 1 |
| Lutetium Lu 177 dotatate | 1 | 0 | 1 |
| Apatinib | 1 | 0 | 1 |
| Mitotane | 1 | 0 | 1 |
| FAPI-46 GA-68 | 0 | 0 | 1 |
| FAPI-46 | 0 | 0 | 1 |
| Nivolumab | 0 | 0 | 1 |
| Cabozantinib | 0 | 0 | 1 |
| Gefitinib | 0 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Dec 2026Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Dec 2026Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma · West China Hospital
- Jan 2027IDOV-Immune for Advanced Solid Tumors · ViroMissile, Inc.
- Jul 2027Agnostic Therapy in Rare Solid Tumors · Instituto do Cancer do Estado de São Paulo
Who these studies take
Of the 16 Adrenal Gland Neoplasms studies recruiting now, 10 (63%) set no upper age limit and 2 (13%) stop at 75 or younger. 6 (38%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (38%) | 6 (38%) |
| 18 | 15 (94%) | 15 (94%) |
| 30 | 16 (100%) | 16 (100%) |
| 40 | 16 (100%) | 16 (100%) |
| 50 | 16 (100%) | 16 (100%) |
| 65 | 16 (100%) | 16 (100%) |
| 75 | 14 (88%) | 14 (88%) |
| 85 | 12 (75%) | 12 (75%) |
Across all 62 studies, recruiting or not: 8% stop at 75 or younger and 3% at 65; 21% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 62. Browse all 62 → or search them.
- Clinical and Molecular Characteristics of Primary Aldosteronism in BlacksRecruitingNCT033742151 country
- Prospective Comprehensive Molecular Analysis of Endocrine NeoplasmsRecruitingNCT010056541 country
- PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical CarcinomaRecruitingNCT05286814Phase 21 country
- Thyroid Health Outcomes Registry for SurgeryNot yet recruitingNCT07812779
- German Adrenocortical Carcinoma RegistryRecruitingNCT004536741 country
- IDOV-Immune for Advanced Solid TumorsRecruitingNCT06910657Phase 12 countries
- Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).RecruitingNCT06607692Phase 1/21 country
- Adrenal Tumors - Pathogenesis and TherapyRecruitingNCT006692661 country
- Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal TumorsEnrolling by invitationNCT071821751 country
- Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical CarcinomaRecruitingNCT06831175Phase 21 country
- 3D Laparoscopic Adrenalectomies for Adrenal TumorsRecruitingNCT049057061 country
- Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic AlterationsRecruitingNCT041275521 country
- National Study of Adrenal TumoursEnrolling by invitationNCT068703961 country
- Impact of Non-magnetic Screen Respiratory Self-guidance During MRI-guided Radiotherapy Sessions for Mobile LesionsRecruitingNCT05783908Not applicable1 country
- Assessment of Metabolic Complications in Patients With Adrenal Tumors Through Radiological ImagesRecruitingNCT068013401 country
- CRISAL Study:Cancer Risk In Secreting Adrenal LesionsRecruitingNCT065201111 country
- Development of Clinical Evidence for Optimal Management of Adrenal Diseases Based on Real-World DataRecruitingNCT062294051 country
- Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted AdrenalectomyRecruitingNCT060500571 country
- The Efficacy and Safety of Chinese Domestic Surgical Robot System in Urological TelesurgeryRecruitingNCT05739812Not applicable1 country
- Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various CancersActive, not recruitingNCT04459273Phase 11 country
- Study of Adrenal Gland TumorsCompletedNCT000059271 country
- 11C-Metomidate PET/CT for Endocrine Hypertension and Characterisation of Adrenal TumoursCompletedNCT06100367Phase 2/31 country
- Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic CancersActive, not recruitingNCT07118176Phase 11 country
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 21 country
- Evaluation of Side Effects of MitotaneActive, not recruitingNCT005681391 country
- Anti-CTLA4-NF mAb (BMS986218), Nivolumab, and Stereotactic Body Radiation Therapy for the Treatment of Metastatic Solid MalignanciesTerminatedNCT04785287Phase 1/21 country
- Combined FDG-PET and 123I-Iodometomidate Imaging for Adrenal NeoplasiaTerminatedNCT02010957Phase 31 country
- Neuroendocrine and Adrenal TumorsWithdrawnNCT04432532
- The Registry of Oncology Outcomes Associated with Testing and TreatmentCompletedNCT040284791 country
- A Randomized Clinical Trial About Use of 3D Laparoscopy Versus 2D Laparoscopy in Adrenal SurgeryCompletedNCT06576336Phase 41 country
- Cabozantinib in Advanced Adrenocortical CarcinomaActive, not recruitingNCT03612232Phase 21 country
- Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings SyndromeTerminatedNCT01246739Not applicable3 countries
- Side-specific Factors for Conversion in Adrenalectomy for Pheochromocytoma.CompletedNCT06330558
- Cryoablation of Bone Metastases From Endocrine TumorsTerminatedNCT03986593Not applicable1 country
- Textbook Outcome in Adrenal NeoplasmsCompletedNCT058887531 country
- Performance of 18F-Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) in the Diagnosis of Indeterminate Adrenal Tumors on Conventional Imaging: A French Prospective Multicentric StudyCompletedNCT01284829Not applicable1 country
- Research on the Effectiveness and Safety of Remote Control of Domestic Surgical Robot System for Urinary SurgeryCompletedNCT04804163Early Phase 11 country
- Efficacy and Safety of Clinical Telesurgery Using Chinese Independently Developed Surgical Robot SystemCompletedNCT04570176Not applicable1 country
- The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)Status unknownNCT038969581 country
- A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal CancersTerminatedNCT01086696Early Phase 11 country
- Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung CancerCompletedNCT01185639Not applicable1 country
- Laparoscopic Adrenalectomy for Large Adrenal Tumors.CompletedNCT038305931 country
- Towards an Easy-to-use Adrenal Cancer/Tumor Identity CardCompletedNCT02672020Not applicable1 country
- Prevention of Conversion in Posterior Retroperitoneal Adrenalectomy by Measuring Preoperative Anatomical ConditionsCompletedNCT040715611 country
- Salivary Free Cortisol Response to Cosyntropin Stimulation Test in Mitotane Treated PatientsStatus unknownNCT03083834Not applicable1 country
- Evaluation of Molecular Markers in Adrenal TumorsTerminatedNCT013486981 country
- Rare Cystic Benign Adrenal IncidentalomasCompletedNCT037399181 country
- Extracolonic Findings on Computed Tomography (CT) ColonographyStatus unknownNCT01465425
- 18FDG PET Textural Indices in Adrenal LesionCompletedNCT034691021 country
- Study of Adrenalectomy Versus Observation for Subclinical HypercortisolismTerminatedNCT02001051Phase 21 country