ClinicalTrials.gg
Enrolling by invitationNCT07182175Updated Sep 19, 2025

Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors

An observational study in Primary Aldosteronism, Adrenal Tumor and Cushing s Syndrome, sponsored by Peking University First Hospital. Enrolling by invitation at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-09-19.

Sponsored by Peking University First Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
150
Ages
18 Years and older
Sex
All
01

Study summary

The main goal of this study is to follow patients with functional adrenal tumors during the time before and after their surgery.

The main questions it aims to answer are:

  • What heart and blood pressure changes do patients with different types of adrenal tumors have before surgery?
  • What factors affect how the heart and blood pressure recover after surgery?
  • Do the heart and blood pressure conditions before surgery influence recovery and the risk of heart or brain problems after surgery?

Patients will have heart ultrasound checks and health monitoring before and after surgery. The results will help doctors choose the right medicines before surgery, better understand possible risks during the operation, and make safer treatment plans for patients with functional adrenal tumors.

02

Conditions studied

  • Primary Aldosteronism
  • Adrenal Tumor
  • Cushing s Syndrome
  • Pheochromocytoma/Paraganglioma (PPGL)
03

In context

Hyperaldosteronism

201 studies on the registry are indexed under Hyperaldosteronism; 93 are open to participants now.

This study's planned enrollment of 150 is below the median of 200 across 103 observational studies indexed under Hyperaldosteronism.

Browse Hyperaldosteronism studies →

Lead sponsor

Peking University First Hospital is the lead sponsor of 390 studies on the registry; 186 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study population consists of patients with functional adrenal tumors who are hospitalized and/or seen in the outpatient clinic of the Department of Urology at Peking University First Hospital.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients diagnosed in the Department of Urology, Peking University First Hospital with pheochromocytoma and paraganglioma (PPGL), primary aldosteronism (PA), or Cushing syndrome (CS);
  • Written obtained.

Exclusion criteria

Exclusion Criteria:

  • Patients with PPGL, PA, or CS who receive medication or conservative treatment and are not eligible for surgical resection;
  • Patients with communication disorders or severe physical impairments such as aphasia, or visual/hearing disabilities;
  • Patients with severe mental illness who cannot cooperate with the study;
  • Pregnant women or patients otherwise deemed unsuitable for participation by the investigators.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
150 participants (estimated)
Target follow-up
48 Weeks
Patient registry
Yes

Groups and cohorts

  • primary aldosteronism
  • Cushing s Syndrome
  • Pheochromocytoma/Paraganglioma (PPGL)
06

What researchers measure

Primary outcomes

  1. Recovery of cardiac function after adrenal surgery

    global longitudinal stress

    Time frame: from enrollment to 4,24,48 weeks after surgery

Secondary outcomes

  1. Recovery of blood pressure after adrenal surgery

    Decrease in 24h average blood pressure

    Time frame: from enrollment to 4,24,48 weeks after surgery

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No — Data cannot be shared, because data from this study may contain potentially or sensitive patient information.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 19, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07182175
Responsible party
Sponsor
First posted
Sep 19, 2025
Start date
Sep 19, 2024
Primary completion
Nov 17, 2024
Completion
May 29, 2026 (estimated)
Last update
Sep 19, 2025

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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No contact was published for this record. The registry link below has the sponsor’s details.

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