DrugBiological
Immunocytokine NHS-IL12 clinical trials
Also written NHS-IL12 and PDS01ADC.
Keep track of what changes. Save the immunocytokine NHS-IL12 studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
8 studies that test it; most in 2020 (2)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2017 | 1 |
| 2020 | 2 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 7
National Cancer Institute (NCI) (6) · EMD Serono Research & Development Institute, Inc. (1) · M.D. Anderson Cancer Center (1)
Often tested with
Tested in the same studies.
Bintrafusp alfa (2) · Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101 (1) · Avelumab (1)
Studies
Open first, then newest update. How each study uses immunocytokine NHS-IL12 is read from its arms, and is right about nine times in ten.
Testing it · 8
- A Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination With the Immunocytokine PDS01ADC in Localized High and Intermediate Risk Prostate Cancer Treated With Androgen Deprivation TherapyRecruitingPhase 2National Cancer Institute (NCI)NCT05361798Written as PDS01ADC
- PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical CarcinomaRecruitingPhase 2National Cancer Institute (NCI)NCT05286814Written as PDS01ADC
- Enzalutamide and PDS01ADC in PET Positive Recurrent Prostate Cancer (pprPC) Without Testosterone Lowering TherapyRecruitingPhase 2National Cancer Institute (NCI)NCT06096870Written as PDS01ADC
- Combination Immunotherapy in Subjects With Advanced HPV Associated MalignanciesCompletedPhase 1/2National Cancer Institute (NCI)NCT04287868Written as NHS-IL12
- Phase II Trial of Combination Immunotherapy in Subjects With Advanced Small Bowel and Colorectal CancersCompletedPhase 2National Cancer Institute (NCI)NCT04491955Written as NHS-IL12
- A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Avelumab in Combination With M9241(NHS-IL12) (JAVELIN IL-12)TerminatedPhase 1EMD Serono Research & Development Institute, Inc.NCT02994953Written as M9241
- Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA TrialWithdrawnPhase 1M.D. Anderson Cancer CenterNCT04756505Written as Immunocytokine NHS-IL12
- NHS-IL12 for Solid TumorsCompletedPhase 1National Cancer Institute (NCI)NCT01417546Written as NHS-IL-12
Given in every arm · 5 — immunocytokine NHS-IL12 is usual care beside what is tested
- PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi SarcomaRecruitingPhase 1/2National Cancer Institute (NCI)NCT04303117Written as PDS01ADC
- A Phase I/II Study of PDS01ADC With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and PDS01ADC With Docetaxel in Castration Resistant Prostate CancerRecruitingPhase 1/2National Cancer Institute (NCI)NCT04633252Written as PDS01ADC
- Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary MalignanciesActive, not recruitingPhase 1National Cancer Institute (NCI)NCT04235777Written as PDS01ADC
- A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersCompletedPhase 1/2National Cancer Institute (NCI)NCT04708470Written as PDS01ADC
- Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas CancerTerminatedPhase 1/2National Cancer Institute (NCI)NCT04327986Written as M9241
Codes
What other systems call immunocytokine NHS-IL12 · ClinicalTrials.gg INT017064
- UNII (FDA) KF6D9Z1MERIMMUNOCYTOKINE NHS-IL12One source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | KF6D9Z1MER | IMMUNOCYTOKINE NHS-IL12 | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.