Acidosis: all 111 studies

Page 1 of 2. Open to participants first (19), then studies with results posted, then the rest; newest registration first within each.

• Frequency of Metabolic Acidosis in the Pediatric Intensive Care UnitNot yet recruitingNCT07803263
• Bicarbonate HD StudyRecruitingNCT07779200
• Pilot Trial of Oral Sodium Bicarbonate Versus Higher Dialysate Bicarbonate in Hemodialysis Patients With Metabolic AcidosisNot yet recruitingNCT07688434Not applicable
• Balanced Crystalloid vs Normal Saline in Pediatric Acute GastroenteritisRecruitingNCT07610382
• Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney InjuryRecruitingNCT07464431Phase 4
• A Study of Tris-Hydroxymethyl Aminomethane (THAM) Versus Sodium Bicarbonate in Cardiac Surgical PatientsRecruitingNCT07424625Phase 4
• A Study to Evaluate the Efficacy and Safety of Veverimer for the Treatment of Metabolic AcidosisRecruitingNCT07355062Phase 3
• Lactic Acidosis and Prior Metformin TreatmentRecruitingNCT07300293
• Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO ApplicationRecruitingNCT07099963
• PLADO for Conservative Management of CKDRecruitingNCT06932042Not applicable
• A Study on Bedside Formate Assay as a Diagnostic Tool in Methanol PoisoningRecruitingNCT06881641
• Prevention of Metabolic Acidosis in Preterm Neonates by Replacing Sodium Chloride With Sodium Acetate in Parenteral NutritionRecruitingNCT06545565Phase 3
• Fluid Administration in Ketoacidosis (DRINK)RecruitingNCT06541535Phase 4
• Adding Urea to the Final Dialysis FluidRecruitingNCT06366230Phase 1/2
• ADVOS® Versus CVVHD in Metabolic or Mixed AcidosisRecruitingNCT05842369Not applicable
• A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 StudyRecruitingNCT05130437Phase 1/2
• Effect of Alkali Therapy on Vascular and Graft Function in Kidney Transplant RecipientsRecruitingNCT05005793Phase 4
• Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKDRecruitingNCT04984226Phase 2
• Open-Label Study of mRNA-3927 in Participants With Propionic AcidemiaRecruitingNCT04159103Phase 1/2
• Bone in CKD Alkali Response (BICARb Pilot Trial)TerminatedNCT05918029Phase 2/3Results posted
• Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney DiseaseTerminatedNCT04727528Phase 3Results posted
• Bicarbonate Administration and Cognitive Function in Midlife and Older Adults With CKDCompletedNCT04600323Early Phase 1Results posted
• Thiamine as Adjunctive Therapy for Diabetic KetoacidosisCompletedNCT03717896Phase 2Results posted
• Long-term Safety Extension to Study TRCA-301CompletedNCT03390842Phase 3Results posted
• Evaluation of TRC101 in Subjects With Metabolic Acidosis Associated With Chronic Kidney DiseaseCompletedNCT03317444Phase 3Results posted
• Bicarbonate Administration in CKDCompletedNCT02915601Not applicableResults posted
• Evaluation of TRC101 in Subjects With Chronic Kidney Disease and Metabolic AcidosisCompletedNCT02809183Phase 1/2Results posted
• Bicarbonate in Patients With Out-of-hospital Cardiac ArrestCompletedNCT02303548Phase 2Results posted
• Metabolic Acidosis and Vascular Function in Patients With Chronic Kidney DiseaseCompletedNCT02031770Not applicableResults posted
• Effectiveness of Subcutaneous Glargine On The Time To Closure of The Anion Gap in Patients Presenting to the Emergency Department With Diabetic Keto-acidosisCompletedNCT02006342Not applicableResults posted
• Alkali Therapy in Chronic Kidney DiseaseCompletedNCT01452412Phase 2/3Results posted
• Clinical Evidence of pH Dependent ß2 Adrenergic Transport Mechanisms in the AirwayCompletedNCT01216748Not applicableResults posted
• Sodium Bicarbonate Supplementation in Chronic Kidney Disease Evaluation of Dose Response, Safety and Beneficial EffectsCompletedNCT00888290Phase 2/3Results posted
• the Effect of Interdialytic Serum Bicarbonate Correction on Vascular Calcification in Hemodialysis PatientsCompletedNCT07765459Phase 1
• A Phase 1 Study, to Evaluate the Effect of ADV7103 on Gastric pH Under Fed and Fasting Conditions in Adult Healthy Participants.CompletedNCT07446881Phase 1
• Clinical Prediction Models for Pediatric In-Hospital Death Risk in Congolese Severe Malaria Children Using Machine Learning Based-AlgorithmsCompletedNCT07355426
• Ephedrine Versus Norepinephrine and Fetal Acid-Base Status During Cesarean Delivery Under Spinal AnesthesiaCompletedNCT06921473Phase 4
• Correlation Between Base Excess in Patients Upon Admission to the ICU and Platelet Count Trend in the Following DaysCompletedNCT06908408
• Hyperlactatemia in Critically Ill Patients With Acute Kidney InjuryCompletedNCT06565403
• Treating Metabolic Acidosis in Chronic Kidney Disease to Prevent Adverse Kidney and Cardiovascular OutcomesCompletedNCT06545461Not applicable
• Diabetic Ketoacidosis Diagnosis and ManagementCompletedNCT06327737
• Explorative Study to Investigate the Acid-base Response to Sodium and Potassium Salts in Patients With Chronic Kidney Disease.Active, not recruitingNCT06237712Not applicable
• Open-glottis Pushing Technique Versus the Valsalva Pushing Technique in the Second Stage of LaborCompletedNCT06210087Not applicable
• Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5CompletedNCT05970094Not applicable
• The Relationship of Developing Metabolic Acidosis With Antiepleptic Drugs in Craniotomy OperationsCompletedNCT05940935
• The Effect of Bicarbonate Profiling in Dialysis Fluid on Phosphate Removal During Hemodialysis and Blood pHCompletedNCT05861700Not applicable
• Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5Status unknownNCT05784389Not applicable
• SODium BICarbonate for Metabolic Acidosis in the ICUActive, not recruitingNCT05697770Phase 3
• The Effects of Hypothermia and Acidosis on Coagulation During Treatment With Rivaroxaban Measured With ROTEMCompletedNCT05669313
• Lactate Metabolism in the Hypoperfused Critically IllStatus unknownNCT05582824
• Efficacy of Plant-protein Diets in Patients With Chronic Kidney DiseaseCompletedNCT05350098Not applicable
• Effects of Isotonic Saline As Irrigation Fluid In Transurethral Resection of Prostate (TUR-P) OperationsStatus unknownNCT05285189
• Value of Fetal Scalp Lactate Sampling During Labour in Cases of Abnormal Fetal Heart RateStatus unknownNCT05259202
• Effect of Flow Rate and PH on Muscle AcidosisTerminatedNCT05165277Not applicable
• Meglimine Sodium Succinate for Correction of Metabolic Acidosis in Critically Ill PatientsCompletedNCT05147051Phase 2
• Reducing Dietary Acid With Food Versus Oral Alkali in People With Chronic Kidney Disease (ReDACKD)CompletedNCT05113641Not applicable
• The Threshold of Serum Anion Gap as a Screening Tool for Organic AcidosisCompletedNCT04975906
• Risk Potential for Organ Dysfunction Associated With Sodium Bicarbonate Therapy (SBT) in Critically Ill PatientsCompletedNCT04953013
• Renal Tubular Disorders in Egyptian ChildrenCompletedNCT04845815
• Optimal Dosage of Acetazolamide for OSA TreatmentCompletedNCT04726982Phase 4
• Placental Transfusion in the 'Natural' Delivery: Effect of Early and Late Umbilical Cord ClampingStatus unknownNCT04459442Not applicable
• The Impact of the pH on Cardiac Function in the Critically Ill PatientCompletedNCT04231045
• Acid-Base Balance, Metabolism and MineralsCompletedNCT04229069Not applicable
• Osteoporosis, Trabecular Bone Score and Fracture Risk Assessment in Male Patients After Radical CystectomyCompletedNCT04153227
• Efficacy of Volume Ventilation in Patients With Acute Respiratory Failure at Risk of Obstructive Apneas or Obesity HypoventilationTerminatedNCT04131660Not applicable
• Evaluation of Respiratory Function in FibromyalgiaCompletedNCT04098731
• The Influences of Dialysate Bicarbonate Concentrations on Hemodialysis PatientsStatus unknownNCT04070690Not applicable
• The Causal Connection Between Sng and Muscle AcidosisStatus unknownNCT04049253Not applicable
• Sodium Bicarbonate for the Treatment of Severe Metabolic Acidosis With Moderate or Severe Acute Kidney Injury in ICUCompletedNCT04010630Not applicable
• Inflammation and Metabolic Acidosis at Birth (AGAIN: AutophaGy AcIdosis Newborn)Status unknownNCT03897101
• High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement TherapyWithdrawnNCT03846258Phase 4
• Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic AcidosisTerminatedNCT03710291Phase 3
• Balanced Solutions and Plasma ElectrolytesCompletedNCT03537898Not applicable
• Major Activation Of NCC in Graft Urinary ExosomesCompletedNCT03503461
• Bicarbonate Administration in Kidney Transplant RecipientsCompletedNCT03428464Not applicable
• Use of Sodium Bicarbonate in Patients Treated With TopiramateStatus unknownNCT03354507Not applicable
• Is Venous to Arterial Conversion (v-TAC) of Blood Gas Reliable in Critical Ill Patients in the ICU?Status unknownNCT03309423
• Preserve-Transplant StudyCompletedNCT03102996Phase 4
• Comparative Analysis Between Ringer's Lactate vs Plasma Lyte-A as Cardiopulmonary Bypass PrimeStatus unknownNCT03043131Phase 3
• Alkalinization by Urologists & NephrologistsCompletedNCT03035812Phase 4
• Introducing Fetal Scalp Stimulation as an Adjunct to Intermittent Auscultation in Low-Resource Settings.CompletedNCT02862925Not applicable
• Fetal Evaluation at Term Using Statistical ECG Signal Processing (FETUSES)TerminatedNCT02835417
• Intraoperative Cell Salvage and Postoperative AcidosisCompletedNCT02800343
• Sodium Bicarbonate to Treat Severe Acidosis in the Critically IllCompletedNCT02476253Phase 3
• Neonatal Acid-Base Status After C Section With Maternal Tilt vs. SupineCompletedNCT02243423Not applicable
• Comparison of High Versus Low Bicarbonate HemodialysisCompletedNCT02098356Not applicable
• Efficacy, Safety Study and Benefit of Alkali Therapy in Sickle Cell DiseaseTerminatedNCT01894594Phase 1
• Effect of the Diet on Urinary Excretion of Alpha-ketoglutarateCompletedNCT01880281Not applicable
• Incidence of Postoperative Ketosis and Metabolic AcidosisStatus unknownNCT01860001
• The Aim of This Investigation is to Compare the Influence of 0.9% Saline and Plasmalyte Solution on Acid-base Balance and Electrolytes in Healthy Patients Undergoing Major Spine Surgeries.CompletedNCT01855542Not applicable
• Effects of Zeolite + Dolomite on Performance and AcidosisCompletedNCT01831492Not applicable
• Dichloroacetate Treatment of Congenital Lactic Acidosis Phase B: Expanded AccessNo longer availableNCT01797276
• Comparison of Standard Versus Low Bicarbonate HemodialysisCompletedNCT01777178Phase 1
• Cadiotocography Combined With ST-analysis Versus Cardiotocography Combined With Scalp-pHTerminatedNCT01699646Not applicable
• Changes in Acid Base Status During High Salt IntakeCompletedNCT01655953Not applicable
• Correction of Metabolic Acidosis in End Stage Renal Disease (ESRD)Status unknownNCT01640119Phase 3
• Ringer's Lactate Versus Normal Saline in Caesarean SectionCompletedNCT01585740Not applicable
• Autologous Stem Cells in Newborns With Oxygen DeprivationStatus unknownNCT01506258Not applicable
• Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood GasesCompletedNCT01467245Not applicable
• Substitution of Propofol by Sevoflurane During Pediatric Cardiopulmonary BypassCompletedNCT01295190

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