An interventional study of Influencer Intervention Videos and Public Domain Messaging Videos in E-Cigarette Use, E-cigarette Use/Vaping Prevention and Vaping Teens, sponsored by Boston Children's Hospital. Not yet recruiting at 1 site in United States. Open to participants aged 13 Years to 21 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-13.
Sponsored by Boston Children's Hospital · Not applicable, Interventional, and Prevention
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Among 287 studies in Vaping with a site in United States — 65 open to participants now, 73 under way, 1 of them phase 3. Vaping · United States.
Among the 287 studies in Vaping with a site in United States, this one is the 15th largest by planned enrollment of the 257 interventional ones that give a count, is one of 21 that started in 2026, is one of 205 with no phase, reaches primary completion later than 28 of the 72 other live ones, and was the 287th registered.
403 studies on the registry are indexed under Vaping; 96 are open to participants now.
Browse Vaping studies →65 of the 287 studies in Vaping with a site in United States are open now. Recruiting first, the newest first:
University of Minnesota · Sites in United States
Ages 21+ · Healthy volunteers
Yale University · Sites in United States
Ages 21–44 · Healthy volunteers
Massachusetts General Hospital · Sites in United States
Ages 18–65
University of Nebraska · Sites in United States
Ages 15–18
Prisma Health-Upstate · Sites in United States
Ages 21+
A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →
Of the 64 Vaping studies recruiting now, 32 (50%) set no upper age limit and 31 (48%) stop at 75 or younger; 13 take children under 18; 40 take healthy volunteers.
This study: 13 Years to 21 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
287 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 18 · Phase 2 21 · Phase 3 4 · Phase 4 12
First in 2013; this study’s year is marked. 21 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 2,556 is above the median of 80 across 323 interventional studies indexed under Vaping.
Median enrollment 71 across the 257 interventional studies, 110 across the 30 observational. Of the 202 that completed or were terminated, 87 (43%) have results posted.
This tab as a report to print or save as PDF → With an account.
30 of 287 have an industry lead sponsor. The 10 most frequent:
Boston Children's Hospital is the lead sponsor of 609 studies on the registry; 148 are open to participants now.
Of its 32 completed or terminated interventional studies of FDA-regulated products, 19 (59%) have results posted.
Boston Children's Hospital has 2 studies filed under Vaping — fewer than ten, so there is no comparison to draw.
30 of the studies in Vaping with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07322432VapeAwayThe CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction | 2026-12 |
| NCT06159608Anna Stanhewicz, PhDSex Differences in the Vascular Effects of E-cigarette Use | 2026-12 |
| NCT04661683University of California, Los AngelesSecondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol | 2026-12-15 |
| NCT07553585Yale UniversitySurvey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes | 2026-12-15 |
| NCT04907136Florida International UniversityDeveloping and Testing Health Warning Labels on the ENDS Device | 2026-12-30 |
Add all 30 to your calendar (.ics) → With an account.
Among the 287 studies in Vaping with a site in United States, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The goal of this interventional study is to test whether short videos of electronic-cigarette (e-cigarette) counter-marketing lessons work to decrease people's intent to use and smoke e-cigarettes. Using short videos, the investigators hope to inform participants about the marketing strategies that e-cigarette companies use to try to get people to purchase and use e-cigarettes. The investigators hope to find that, after watching the short videos, people will be able to point out when e-cigarette companies are trying to sell their products, and hopefully they will have a lower interest in buying and using e-cigarettes. The investigators also hope participants will learn more about the addictiveness and harmfulness of using e-cigarettes by watching the short videos.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Participants in this arm will receive a novel intervention developed by the study team.
Other: Influencer Intervention Videos
Participants will receive a comparable, pre-existing intervention not developed by the study team.
Other: Public Domain Messaging Videos
Participants will receive a control condition that was not developed by the study team.
Other: Influencer Control Videos
Participants will view 4 short-form videos filmed by influencers. Influencers convey messaging designed to counter e-cigarette marketing in retail stores.
Participants will view 1 video in the public domain with messaging on e-cigarette marketing tactics.
Participants will view 4 short-form influencer-generated videos on topics that are unrelated to counter e-cigarette marketing in retail stores.
Susceptibility to use e-cigarettes among those who never used
Susceptibility to use e-cigarettes among those who never used \[Susceptibility scores are calculated based on the following 4 items: 1. Do you think you will try/ use a nicotine vape in the next year? 2. Do you think that you will try/use a nicotine vape soon? 3. If one of your best friends were to offer you a nicotine vape, would you try/use it? 4. Have you ever been curious about trying/using a nicotine vape? Response options for the first three items are: 1 = definitely not, 2 = probably not, 3 = probably yes, and 4 = definitely yes, and for the fourth item were: 1 = not at all curious, 2 = a little curious, 3 = somewhat curious, and 4 = very curious. Per Persoskie and O'Brien (2022), the four items are averaged to create a single index.\] O'Brien EK, Baig SA, Persoskie A. Developing and Validating Measures of Absolute and Relative E-Cigarette Product Risk Perceptions: Single Items Can Be Surprisingly Comprehensive. Nicotine Tob Res. 2022;24(3):316-323. doi:10.1093/ntr/n
Time frame: From Day 1 (Baseline/Pre-intervention) to Day 31 (One-month follow-up after the treatment).
E-cigarette Use
1. Have you EVER used any of the following products, even one or two puffs 2. During the PAST 30 DAYS, have you used any of the following products, even one or two puffs? 3. During the PAST 30 DAYS, on how many days (from 0 days to 30 days) did you use a… (numeric response) 4. During the PAST 7 DAYS, have you used any of the following products, even one or two puffs? 5. During the PAST 7 DAYS, on how many days (from 0 days to 7 days) did you use a… 6. Other questions on age at first use, friend use and family use. All questions relate to the following products: * Nicotine vape * Some kind of vape (Don't know what was in it) * Cigarette * Nicotine pouch
Time frame: From Day 1 (Baseline/Pre-intervention) to Day 31 (One-month follow-up after the treatment).
Intent to use e-cigarettes and cigarettes
Do participants plan to use e-cigarettes and cigarettes?
Time frame: From Day 1 (Baseline/Pre-intervention); Day 1 (Immediately Post-intervention); and Day 31 (One-month follow-up after the treatment)
Vaping attitudes and norms
We will measure people's attitudes and acceptance towards vaping using: Vaping Attitudes Scale (5-point Likert-type; high score: positive attitude) and Mean Vaping Injunctive Norms Scale (3-item)
Time frame: From Day 1 (Baseline/Pre-intervention); Day 1 (Immediately Post-intervention); and Day 31 (One-month follow-up after the treatment)
Pro-vaping marketing exposure (focused on retail), including marketing receptivity
Can people understand and recognize e-cigarette marketing? Does it have an effect on them?
Time frame: From Day 1 (Baseline/Pre-intervention) Day 31 (One-month follow-up after the treatment)
Marketing exposure on social media
Questions to assess social media use, frequency, and platforms.
Time frame: Day 1 (Baseline/Pre-intervention)
Anti-vaping content exposure
Prior exposure to having seen content that dissuades people from using vapes and locations where they saw it.
Time frame: Day 1 (Baseline/Pre-intervention)
Knowledge of e-cigarette retail marketing
How much do people know about e-cigarette retail marketing (based on key messages and facts shown in video content)?
Time frame: From Day 1 (Baseline/Pre-intervention); Day 1 (Immediately Post-intervention); and Day 31 (One-month follow-up after the treatment)
Perceived message effectiveness
We will test the effectiveness of the videos using two scales, the Message Assessment Scale for Tobacco Prevention Campaigns, and the Perceived Message Effectiveness Scale (6-item).
Time frame: Day 1 (Immediately post-intervention)
Video acceptability
We will test how much people enjoyed and connected with the videos based on a quality rating scale and a question on alternative ways to receive content.
Time frame: Day 1 (Immediately post-treatment)
Recruitment, enrollment, and attrition
We want to measure recruitment and enrollment success, and how many people complete the study.
Time frame: From Day 1 (Baseline/Pre-intervention); Day 1 (Immediately Post-intervention); and Day 31 (One-month follow-up after the treatment)
Video feasibility
We want to test whether people were able to watch the videos, how many of them they watched and for how long, and what devices they used to watch them.
Time frame: Day 1 (Immediately post-intervention)
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Nov 2026; primary completion for Apr 2027, 5 months later.
Of 184 non-industry interventional studies with no phase under Vaping, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 35. This study's planned 5 months is below that.
Counting every sponsor, half of 208 studies reached it within 18 months; a quarter within 6 and three quarters within 31.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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