An interventional study of Virtual Reality Application and Standard Care (in control arm) in Acute Stroke and Psychomotor Agitation, sponsored by Ankara Etlik City Hospital. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2026-08-26.
Sponsored by Ankara Etlik City Hospital · Not applicable, Interventional, and Supportive care
Help build ClinicalTrials.gg — short surveys, remote interviews or testing, in your language. Take part →
Among 484 studies in Stroke with a site in Turkey — 95 open to participants now, 107 under way, 3 of them phase 3. Stroke · Turkey.
Among the 484 studies in Stroke with a site in Turkey, this one is the 63rd largest by enrollment of the 320 interventional ones that give a count, is one of 71 that started in 2025, is one of 291 with no phase, and was the 472nd registered.
8,258 studies on the registry are indexed under Stroke; 2,055 are open to participants now.
Browse Stroke studies →95 of the 484 studies in Stroke with a site in Turkey are open now. Recruiting first, the newest first:
Izmir City Hospital · Sites in Turkey
Ages 18–90
Izmir City Hospital · Sites in Turkey
Ages 18–90
Istanbul University - Cerrahpasa · Sites in Turkey
Ages 18–75
Bitlis Eren University · Sites in Turkey
Ages 18–75
Istinye University · Sites in Turkey
Ages 40–70
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 1,415 Stroke studies recruiting now, 695 (49%) set no upper age limit and 280 (20%) stop at 75 or younger; 77 take children under 18; 195 take healthy volunteers.
This study: 18 Years to 90 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
484 studies; the count open now beside each. This study's row is marked.
First in 1998; this study’s year is marked. 71 started in 2025.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 68 is above the median of 49 across 6,027 interventional studies indexed under Stroke.
Median enrollment 40 across the 320 interventional studies, 63 across the 164 observational. Of the 338 that completed or were terminated, 22 (7%) have results posted.
This tab as a report to print or save as PDF → With an account.
29 of 484 have an industry lead sponsor. The 10 most frequent:
Ankara Etlik City Hospital is the lead sponsor of 176 studies on the registry; 77 are open to participants now.
Ankara Etlik City Hospital has 9 studies filed under Stroke — fewer than ten, so there is no comparison to draw.
34 of the studies in Stroke with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07551141Bitlis Eren UniversityEffects of Plantar Vibration on Gait and Balance in Stroke | 2026-11 |
| NCT07550270Gaziler Physical Medicine and Rehabilitation Education and Research HospitalBody Weight-Supported and Virtual Reality Gait Training in Stroke Patients | 2026-11 |
| NCT07565363Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research HospitalThe Effect of Motor Imagery on Upper Extremity Function in Stroke Rehabilitation | 2026-11-20 |
| NCT06166862Karamanoğlu Mehmetbey UniversityAction Observation and Motor Imagery Therapy in Stroke | 2026-12 |
| NCT07822854Nermin KARTVagal Stimulation in Individuals With Stroke | 2026-12-01 |
Add all 34 to your calendar (.ics) → With an account.
Among the 484 studies in Stroke with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This randomized controlled, single-blind study evaluates the effect of a Virtual Reality (VR) application on agitation levels and physiological vital signs in patients with acute stroke. Participants are randomly assigned to an intervention group receiving standard clinical care plus structured VR sessions, or a control group receiving standard clinical care alone. Agitation scores and vital signs (heart rate, blood pressure, respiratory rate, and oxygen saturation) are measured pre- and post-intervention to evaluate the outcomes of VR therapy.
Stroke is a sudden medical condition that affects the brain. During the acute phase of a stroke, many patients experience agitation, which means feeling restless, anxious, or uncooperative. Agitation can complicate medical care and negatively affect a patient's recovery and vital signs (such as heart rate and blood pressure).
The main purpose of this study is to evaluate whether using a Virtual Reality (VR) application helps reduce agitation levels and stabilize vital signs in individuals who have experienced an acute stroke.
This is a randomized controlled, single-blind clinical trial. Participants with acute stroke will be randomly assigned to one of two groups:
Intervention Group: Participants will receive a structured Virtual Reality (VR) application session in addition to their routine stroke care.
Control Group: Participants will receive standard routine clinical care and monitoring without the VR application.
Researchers will measure and compare the participants' agitation levels using a clinical evaluation scale before and after the intervention. In addition, physiological vital signs (including heart rate, blood pressure, respiratory rate, and oxygen saturation) will be closely monitored to determine the effects of the VR therapy.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
* Individuals who have passed 48 hours post-acute CVA (being in the acute phase of stroke treatment, stroke duration not exceeding the first 4 weeks)
Exclusion Criteria:
Presence of nausea and vomiting
Participants in this arm receive structured Virtual Reality (VR) application sessions in addition to standard clinical stroke care and management.
Behavioral: Virtual Reality Application
Participants in this arm receive standard routine clinical stroke care and monitoring alone, without any Virtual Reality intervention.
Other: Standard Care (in control arm)
Participants receive structured Virtual Reality (VR) relaxation and distraction sessions in addition to standard clinical stroke care to manage post-stroke agitation.
Participants receive routine standard clinical stroke care and monitoring alone without any Virtual Reality intervention.
Change in Body Temperature
Assessment of body temperature (°C) evaluated across three time points.
Time frame: Baseline (pre-intervention), immediately post-intervention, and 1 hour post-intervention
Change in Heart Rate
Assessment of heart rate (beats/min) evaluated across three time points.
Time frame: Baseline (pre-intervention), immediately post-intervention, and 1 hour post-intervention
Change in Blood Pressure
Assessment of blood pressure (mmHg) evaluated across three time points.
Time frame: Baseline (pre-intervention), immediately post-intervention, and 1 hour post-intervention
Change in Respiratory Rate
Assessment of respiratory rate (breaths/min) evaluated across three time points.
Time frame: Baseline (pre-intervention), immediately post-intervention, and 1 hour post-intervention
Change in Oxygen Saturation
Assessment of oxygen saturation (SpO2, %) evaluated across three time points.
Time frame: Baseline (pre-intervention), immediately post-intervention, and 1 hour post-intervention
Change in Agitation Levels
Agitation levels evaluated using a validated clinical agitation rating scale across three time points (pre-intervention, immediately post-intervention, and post-intervention) to assess changes in patient agitation.
Time frame: Baseline (pre-intervention), immediately post-intervention, and 1 hour post-intervention
Plan to share: No — Individual participant data will not be shared in order to protect participant confidentiality and privacy in accordance with ethical board guidelines and informed consent agreements.
No publications or documents are linked to this record.
Ran from Sep 2025 to primary completion in Jun 2026, 9 months.
Of 3,111 non-industry interventional studies with no phase under Stroke, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 46. This study's 9 months is below that.
Counting every sponsor, half of 3,255 studies reached it within 23 months; a quarter within 10 and three quarters within 46.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.