Psychomotor Agitation clinical trials
The registry lists 231 studies for Psychomotor Agitation across more than 10 countries. 28 are recruiting or about to start. 75 of them are mainly about Psychomotor Agitation (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
BioXcel Therapeutics Inc (11) · Otsuka Pharmaceutical Development & Commercialization, Inc. (10) · Hennepin Healthcare Research Institute (5) · Axsome Therapeutics, Inc. (5) · Alexza Pharmaceuticals, Inc. (4) · Ain Shams University (3) · University Hospital, Clermont-Ferrand (3) · New York State Psychiatric Institute (3)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type · Phase 3 · Suven Life Sciences Limited
- Nov 2026Clinical Trial on Agitation in Alzheimer's Dementia · IGC Pharma, LLC
- Dec 2026Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia · Mclean Hospital
- Dec 2026Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac Surgery · University of British Columbia
- Dec 2026PARO-agitation-study · Hannover Medical School
- Apr 2027the Multi-modal Evaluation of Agitation in Critically Ill Patients Based on Remote Video-Ultra-sensitive Detection Wave · Second Affiliated Hospital, School of Medicine, Zhejiang University
- May 2027Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's Type · Teikoku Pharma USA, Inc.
- May 2027Effect of Daily Screen Time on Postoperative Emergence Delirium in Children Aged 2-11 Years · Kanuni Sultan Suleyman Training and Research Hospital
- Jun 2027Protocolized Receptive Music Intervention to Reduce Care Refusal in Nursing Home Residents With Major Neurocognitive Disorders · LNA SANTE
- Aug 2027Weighted Blankets for Agitation in Adults in the Intensive Care Unit · Anmed Health
Who these studies take
Of the 20 Psychomotor Agitation studies recruiting now, 8 (40%) set no upper age limit and 7 (35%) stop at 75 or younger. 4 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (15%) | 3 (15%) |
| 18 | 12 (60%) | 12 (60%) |
| 30 | 12 (60%) | 12 (60%) |
| 40 | 12 (60%) | 12 (60%) |
| 50 | 12 (60%) | 12 (60%) |
| 65 | 15 (75%) | 15 (75%) |
| 75 | 13 (65%) | 13 (65%) |
| 85 | 13 (65%) | 13 (65%) |
Across all 231 studies, recruiting or not: 36% stop at 75 or younger and 32% at 65; 23% take children; 1% are for women only and <1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Psychomotor Agitation studies take
Of 23 phase 3 interventional studies under Psychomotor Agitation, half reached primary completion within 41 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 41 mo24–47 · 23 studies | — | — |
| Phase 4 | 12 mo10–21 · 12 studies | — | — |
| Interventional, no phase | 17 mo6–42 · 36 studies | — | 17 mo6–42 · 36 studies |
| Observational | 12 mo10–32 · 19 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered3
- Pharmacokinetics and Relative Bioavailability of Intranasal vs Intramuscular Olanzapine in Healthy Adult ParticipantsNov 6, 2026NCT07921966
- Weighted Blankets for Agitation in Adults in the Intensive Care UnitNov 5, 2026NCT07920497
- Virtual Reality to Advance Dementia Care and Quality of LifeOct 26, 2026NCT07893678
Studies
Recruiting first, then most recently updated. Showing 50 of 231. Browse all 231 → or search them.
- A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)RecruitingNCT06937229Phase 326 countries
- Nabilone for Agitation Blinded Intervention TrialRecruitingNCT04516057Phase 31 country
- A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's DiseaseRecruitingNCT07011745Phase 314 countries
- Virtual Reality to Advance Dementia Care and Quality of LifeNot yet recruitingNCT07893678Not applicable1 country
- Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's DiseaseRecruitingNCT06808984Phase 24 countries
- Neurosteer Bedside Monitoring SystemRecruitingNCT06718764Not applicable1 country
- Safety and Efficacy of Esketamine - Dexmedetomidine Combination Versus Dexmedetomidine Monotherapy for Hyperactive Delirium in ICU Patients on Non-Invasive Respiratory Support (SEED-NIRS Trial): Study Protocol of a Randomized Controlled TrialNot yet recruitingNCT07377981Phase 41 country
- A Multicomponent Intervention Program to Prevent and Reduce ICU Agitation and Physical Restraint UseRecruitingNCT05783505Not applicable1 country
- Effect of Daily Screen Time on Postoperative Emergence Delirium in Children Aged 2-11 YearsRecruitingNCT075528961 country
- Protocolized Receptive Music Intervention to Reduce Care Refusal in Nursing Home Residents With Major Neurocognitive DisordersRecruitingNCT07730957Not applicable1 country
- Melatonin for Post Tonsillectomy Emergence Agitation in PediatricRecruitingNCT07375342Not applicable1 country
- Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.RecruitingNCT06781333Phase 21 country
- Clinical Trial of Peer Support in the ED (PCORI)Not yet recruitingNCT06556069Not applicable1 country
- PARO-agitation-studyRecruitingNCT07568093Not applicable1 country
- The Effect of Therapeutic Touch on Agitation, Pain, and Cortisol Levels in Intensive Care PatientsNot yet recruitingNCT07061340Not applicable1 country
- Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients.RecruitingNCT055226471 country
- Responsive Nature-Driven Imagery to Reduce Delirium After Cardiac SurgeryNot yet recruitingNCT07051096Not applicable1 country
- Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain InjuryNot yet recruitingNCT06993194Not applicable
- Acute Agitation in Emergency PsychiatryRecruitingNCT06752616Phase 2/31 country
- Effects of Dexmedetomidine on Agitation in Critically Ill TBI PatientsNot yet recruitingNCT06620393Phase 2/3
- the Multi-modal Evaluation of Agitation in Critically Ill Patients Based on Remote Video-Ultra-sensitive Detection WaveRecruitingNCT065436021 country
- Evaluation of The Relationship Between Perioperative Hypothermia and Emergence AgitationRecruitingNCT065431341 country
- Safe Brain Initiative, Operationalizing Precision AnaesthesiaRecruitingNCT057651621 country
- Individualized Music Playlist Based on ISO Principle for De-escalation of Agitation in DementiaNot yet recruitingNCT06104436Not applicable1 country
- A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)RecruitingNCT061403421 country
- Evaluating Sublingual Dexmedetomidine For Moderate To Severe Agitation In Inpatients With Schizophrenia Or Bipolar DisorderRecruitingNCT06093451Phase 41 country
- Premature Enhanced Automated Capture of Comfort KnowledgeRecruitingNCT060376291 country
- Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM)RecruitingNCT038800841 country
- Weighted Blankets for Agitation in Adults in the Intensive Care UnitActive, not recruitingNCT07920497Not applicable1 country
- Efficiency of E-learning and Role-playing for the Training of Nursing Home Caregivers in the Support of Agitation in Neurodegenerative DiseasesCompletedNCT049371271 country
- Dexmedetomidine Transdermal Systems (DMTS) Treatment for Agitation Associated With Dementia of the Alzheimer's TypeActive, not recruitingNCT06052254Phase 21 country
- Virtual Reality to Reduce Anxiety, Agitation and Delirium in Critically Ill PatientsCompletedNCT07649876Not applicable1 country
- Assessment of Acute Psychomotor Agitation Measures Associated With Schizophrenia and Bipolar DisorderCompletedNCT07116694Phase 21 country
- Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III)TerminatedNCT05665088Phase 31 country
- Clinical Trial on Agitation in Alzheimer's DementiaActive, not recruitingNCT05543681Phase 23 countries
- Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's TypeActive, not recruitingNCT05397639Phase 34 countries
- Baclofen to Prevent Agitation in Alcohol Addicted Patients in ICUCompletedNCT02723383Phase 31 country
- Life's End Benefits of cannaBidiol and tetrahYdrocannabinolCompletedNCT05644262Phase 21 country
- Family Videos and Virtual Reality in Intensive Care PatientsCompletedNCT07794696Not applicable1 country
- Effect of Virtual Reality on Agitation in Acute StrokeCompletedNCT07787910Not applicable1 country
- A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease AgitationCompletedNCT05557409Phase 32 countries
- Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar DisorderCompletedNCT06041646Phase 41 country
- An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With DementiaTerminatedNCT05276830Phase 21 country
- Dexmedetomidine in the Treatment of Agitation Associated With Bipolar DisorderCompletedNCT04276883Phase 31 country
- Study of BXCL501 In Agitation Associated With Delirium in ICU PatientsWithdrawnNCT05313386Phase 21 country
- Sub-Lingual Dexmedetomidine in Agitation Associated With SchizophreniaCompletedNCT04010305Phase 11 country
- Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)CompletedNCT05271552Phase 31 country
- Dexmedetomidine in the Treatment of Agitation Associated With SchizophreniaCompletedNCT04268303Phase 31 country
- Sub-Lingual Dexmedetomidine in Agitation Associated With DementiaCompletedNCT04251910Phase 1/21 country
- Impact of Harp Therapy on Behavioral Disorders in Nursing Home Residents With Neurodegenerative Disease (ARPE)CompletedNCT077480131 country