An observational study in Stroke, Ideomotor Apraxia and Hemiplegia, sponsored by Izmir City Hospital. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2026-10-19.
Sponsored by Izmir City Hospital · Observational
After a stroke, some people have difficulty planning and carrying out familiar movements. This difficulty is called ideomotor apraxia and cannot be explained by muscle weakness alone. It may influence how people improve during rehabilitation.
This study will examine whether ideomotor apraxia is associated with changes in walking, balance, and independence in adults receiving rehabilitation after stroke at Izmir City Hospital.
Participants will be assessed for apraxia before rehabilitation and followed during their usual rehabilitation program, which includes conventional rehabilitation and RehaWalk-supported gait training. Walking and other functional abilities will be evaluated before and after the rehabilitation program. Changes will be compared between participants with and without apraxia.
The study will observe routine care. Participants will not be assigned to different treatments, and no experimental treatment will be provided. The findings may help clinicians understand whether apraxia is useful for predicting rehabilitation outcomes after stroke.
This single-center, prospective observational cohort study will investigate the prognostic association between baseline ideomotor apraxia and functional changes following routine conventional rehabilitation and RehaWalk-supported gait rehabilitation in adults with stroke at Izmir City Hospital.
Ideomotor apraxia will be assessed before rehabilitation using the Test of Upper Limb Apraxia (TULIA; score range 0-240). Participants scoring below 194 will form the apraxia cohort and those scoring 194 or above the non-apraxia cohort. TULIA scores will also be analyzed as a continuous measure to examine the relationship between apraxia severity and functional gains.
Rehabilitation will be delivered according to routine clinical practice: conventional inpatient rehabilitation plus RehaWalk-supported gait training, 3 sessions per week for up to 5 weeks (15 sessions, 30 minutes each). Participants completing at least 12 sessions will be included in the analysis. The study will not assign treatment, introduce an additional rehabilitation method, or provide an experimental intervention.
Assessments will be performed at baseline and after the 15th session or at discharge, whichever comes first. TULIA will be administered by a physician investigator and recorded separately; outcome assessors will be blinded to apraxia group status.
Functional changes will be compared between cohorts. Multivariable linear regression will examine whether baseline apraxia is independently associated with change in gait speed after adjusting for age, time since stroke, lesion side, baseline motor function, baseline 10-Meter Walk Test and number of completed sessions.
7,441 studies on the registry are indexed under Stroke; 2,012 are open to participants now.
This study's planned enrollment of 60 is below the median of 160 across 1,729 observational studies indexed under Stroke.
Browse Stroke studies →Izmir City Hospital is the lead sponsor of 25 studies on the registry; 12 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adults with clinically and radiologically confirmed ischemic or hemorrhagic stroke receiving inpatient rehabilitation at the Physical Medicine and Rehabilitation Clinic of Izmir City Hospital and scheduled for routine RehaWalk-supported gait rehabilitation. Eligible patients who provide written informed consent will be enrolled consecutively. Participants will be classified into cohorts with or without ideomotor apraxia according to baseline TULIA scores.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Adults with stroke whose baseline Test of Upper Limb Apraxia (TULIA) total score is below 194. Participants receive routine conventional rehabilitation and RehaWalk-supported gait rehabilitation.
Adults with stroke whose baseline Test of Upper Limb Apraxia (TULIA) total score is 194 or above. Participants receive routine conventional rehabilitation and RehaWalk-supported gait rehabilitation.
Change in Walking Speed on the 10-Meter Walk Test
Walking speed will be assessed using the 10-Meter Walk Test and expressed in meters per second. Change will be calculated as the post-rehabilitation value minus the baseline value. Positive values indicate improved walking speed. Changes will be compared between participants with ideomotor apraxia (baseline TULIA score below 194) and those without ideomotor apraxia (baseline TULIA score of 194 or above).
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in Berg Balance Scale Score
Functional balance will be assessed using the 14-item Berg Balance Scale. Total scores range from 0 to 56, with higher scores indicating better balance. Change will be calculated as the post-rehabilitation score minus the baseline score. Positive changes indicate improvement and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in Timed Up and Go Test Time
Functional mobility will be assessed by measuring the time in seconds required to rise from a chair, walk 3 meters, turn, walk back, and sit down. Change will be calculated as the post-rehabilitation time minus the baseline time. Negative changes indicate improved functional mobility and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in Functional Ambulation Categories Score
Walking independence will be assessed using the Functional Ambulation Categories. Scores range from 0 to 5, with higher scores indicating greater walking independence. Change will be calculated as the post-rehabilitation score minus the baseline score. Positive changes indicate improvement and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in Functional Independence Measure Total Score
Functional independence will be assessed using the 18-item Functional Independence Measure. Total scores range from 18 to 126, with higher scores indicating greater independence. Change will be calculated as the post-rehabilitation score minus the baseline score. Positive changes indicate improvement and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in Fugl-Meyer Assessment Lower Extremity Motor Score
Lower extremity motor function will be assessed using the lower extremity motor domain of the Fugl-Meyer Assessment. Scores range from 0 to 34, with higher scores indicating better motor function. Change will be calculated as the post-rehabilitation score minus the baseline score. Positive changes indicate improvement and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in RehaWalk-Measured Gait Speed
Gait speed recorded by the RehaWalk system will be expressed in meters per second. Change will be calculated as the post-rehabilitation value minus the baseline value. Positive changes indicate increased gait speed. Changes will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in RehaWalk-Measured Cadence
Cadence recorded by the RehaWalk system will be expressed in steps per minute. Change will be calculated as the post-rehabilitation value minus the baseline value. Changes will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in RehaWalk-Measured Step Length
Step length recorded by the RehaWalk system will be expressed in centimeters. Change will be calculated as the post-rehabilitation value minus the baseline value. Changes will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in RehaWalk-Measured Step Symmetry Index
Step symmetry between the paretic and non-paretic sides will be assessed using the symmetry index recorded by the RehaWalk system and expressed as a percentage, with 0% indicating perfect symmetry. Change will be calculated as the post-rehabilitation value minus the baseline value. Negative changes indicate improved symmetry and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in RehaWalk-Measured Double Support Time
Double support time, representing the portion of the gait cycle during which both feet are in contact with the walking surface, will be recorded by the RehaWalk system and expressed as a percentage of the gait cycle. Change will be calculated as the post-rehabilitation value minus the baseline value. Negative changes indicate improvement and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Change in RehaWalk-Recorded Walking Distance Per Session
Walking distance completed during a single RehaWalk session will be expressed in meters. Change will be calculated as the distance in the final session minus the distance in the first session. Positive changes indicate improvement and will be compared between participants with and without ideomotor apraxia.
Time frame: Baseline and after the 15th rehabilitation session or at discharge, whichever comes first (up to 5 weeks)
Plan to share: No — Individual participant data will not be shared publicly due to confidentiality requirements of the institutional ethics committee. De-identified data may be made available by the study director upon reasonable request after publication of the results.
No publications or documents are linked to this record.
Start is estimated for Oct 2026; primary completion for Sep 2027, 11 months later.
Of 787 non-industry observational studies under Stroke, half reached primary completion within 43 months of starting (the median), counting those still running; a quarter within 18 and three quarters within 101. This study's planned 11 months is below that.
Counting every sponsor, half of 833 studies reached it within 41 months; a quarter within 18 and three quarters within 92.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Izmir City Hospital