An interventional study of Respiratory Physiotherapy and Progressive Muscle Relaxation in Cardiac Surgery, Dyspnea and Anxiety, sponsored by Istanbul Aydın University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-10-27.
Sponsored by Istanbul Aydın University · Not applicable, Interventional, and Treatment
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Among 84 studies in Dyspnea with a site in Turkey — 16 open to participants now, 20 under way, none of them phase 3. Dyspnea · Turkey.
Among the 84 studies in Dyspnea with a site in Turkey, this one is the 8th largest by enrollment of the 60 interventional ones that give a count, is one of 8 that started in 2026, is one of 58 with no phase, and was the 74th registered.
894 studies on the registry are indexed under Dyspnea; 188 are open to participants now.
Browse Dyspnea studies →16 of the 84 studies in Dyspnea with a site in Turkey are open now. Recruiting first, the newest first:
Mersin University · Sites in Turkey
Ages 18+
Alper Kemal Gürbüz · Sites in Turkey
Ages 18+ · Healthy volunteers
University of Gaziantep · Sites in Turkey
Ages 18–65
Emine ŞAHİN · Sites in Turkey
Ages 1–17
Izmir Democracy University · Sites in Turkey
Ages 6–18
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 125 Dyspnea studies recruiting now, 69 (55%) set no upper age limit and 41 (33%) stop at 75 or younger; 18 take children under 18; 23 take healthy volunteers.
This study: 18 Years to 80 Years · all sexes · no healthy volunteers.
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84 studies; the count open now beside each. This study's row is marked.
First in 2009; this study’s year is marked. 8 started in 2026.
This study's enrollment of 116 is above the median of 50 across 587 interventional studies indexed under Dyspnea.
Median enrollment 60 across the 60 interventional studies, 77 across the 24 observational. Of the 60 that completed or were terminated, 2 (3%) have results posted.
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2 of 84 have an industry lead sponsor. The 10 most frequent:
Istanbul Aydın University is the lead sponsor of 70 studies on the registry; 18 are open to participants now.
Istanbul Aydın University has 2 studies filed under Dyspnea — fewer than ten, so there is no comparison to draw.
5 of the studies in Dyspnea with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07752706Istanbul University - CerrahpasaBreathing Exercises for Dyspnea and Anxiety in Heart Failure | 2026-12-05 |
| NCT07183956Muğla Sıtkı Koçman UniversityComparison of the Silverman-Andersen Score and the Downes Score | 2026-12-15 |
| NCT06984679Izmir Democracy UniversityPhysical Impairments in Children With Cystic Fibrosis | 2027-03-01 |
| NCT07805603Medipol UniversityHERMES: Quality and Safety of Advanced Respiratory Support During Patient Transport | 2027-06-01 |
| NCT07808658Mersin UniversityEffect of Box Breathing Before Chest Tube Removal After Open-Heart Surgery | 2027-10-22 |
Add all 5 to your calendar (.ics) → With an account.
Among the 84 studies in Dyspnea with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study aims to evaluate the effects of respiratory physiotherapy combined with progressive muscle relaxation exercises on dyspnea, anxiety, hemodynamic status, and delirium symptoms in patients after cardiac surgery. This randomized controlled trial will include 116 patients who will be randomly assigned to an intervention group or a control group. The intervention group will receive respiratory physiotherapy and progressive muscle relaxation exercises in addition to routine postoperative care for 30 minutes per day over eleven days, while the control group will receive routine care only. Outcome measures will include dyspnea assessed by the Modified Borg Scale, anxiety assessed by the State-Trait Anxiety Inventory, hemodynamic parameters obtained from vital signs, and delirium symptoms assessed using the Nursing Delirium Screening Scale. It is hypothesized that the combined intervention will reduce dyspnea and anxiety levels, improve hemodynamic stability, and decrease delirium symptoms. The findings are expected to contribute to improved postoperative recovery and reduced complication risks following cardiac surgery.
This study is designed as a randomized controlled trial to investigate the effects of respiratory physiotherapy combined with progressive muscle relaxation exercises on dyspnea, anxiety, hemodynamic status, and delirium symptoms in patients following cardiac surgery. A total of 116 adult patients who have undergone cardiac surgery will be recruited and randomly allocated into two groups: an intervention group and a control group.
The intervention group will receive respiratory physiotherapy techniques, including breathing exercises, postural drainage, percussion, and vibration, together with progressive muscle relaxation exercises, in addition to routine postoperative care. These interventions will be applied for 30 minutes per day over eleven consecutive days in the postoperative period. The control group will receive only routine postoperative care and standard cardiac rehabilitation procedures.
Outcome measures will include dyspnea assessed using the Modified Borg Scale, anxiety assessed using the State-Trait Anxiety Inventory, hemodynamic parameters including blood pressure, heart rate, respiratory rate, and oxygen saturation obtained from routine vital sign monitoring, and delirium symptoms assessed using the Nursing Delirium Screening Scale. Data will be collected at baseline and after the intervention period.
Inclusion criteria include patients aged 18 years and older who have undergone cardiac surgery and are able to participate in the interventions. Patients with severe orthopedic limitations, communication barriers, or medical contraindications to the interventions will be excluded. Participants may withdraw from the study at any time, and all procedures will be conducted in accordance with ethical standards and patient safety principles.
Randomization will be performed using a computer-based randomization method, and participants will be assigned to groups in a 1:1 ratio. Statistical analysis will be conducted using appropriate parametric and non-parametric tests, with a significance level set at p \< 0.05.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
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You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants in this group will receive routine postoperative care and standard cardiac rehabilitation without additional respiratory physiotherapy or progressive muscle relaxation exercises.
Other: Routine Care
Participants in this group will receive respiratory physiotherapy techniques, including breathing exercises, postural drainage, percussion, and vibration, combined with progressive muscle relaxation exercises in addition to routine postoperative care. The intervention will be applied for 30 minutes per day over three consecutive days following cardiac surgery.
Other: Respiratory Physiotherapy · Other: Progressive Muscle Relaxation
Respiratory physiotherapy includes breathing exercises, postural drainage, percussion, and vibration techniques aimed at improving pulmonary function, facilitating secretion clearance, and enhancing oxygenation in postoperative cardiac surgery patients.
Progressive muscle relaxation is a systematic technique involving sequential contraction and relaxation of muscle groups combined with controlled breathing, aimed at reducing anxiety, improving psychological well-being, and promoting physiological relaxation.
Standard postoperative care and routine cardiac rehabilitation without additional respiratory physiotherapy or progressive muscle relaxation exercises.
Dyspnea (Modified Borg Scale)
Dyspnea severity will be assessed using the Modified Borg Scale (MBS). The scale ranges from 0 (no dyspnea) to 10 (maximal dyspnea). Higher scores indicate greater perceived breathlessness. Measurements will be performed by a trained assessor under standardized conditions.
Time frame: Within the first 24 hours after cardiac surgery (pre-intervention) and immediately after the intervention (post-intervention, same day)
Plan to share: No — Individual participant data (IPD) will not be shared. The study does not include a plan for sharing de-identified individual-level data due to institutional policies and ethical considerations.
No publications or documents are linked to this record.
Ran from May 2026 to primary completion in Jul 2026, 2 months.
Of 268 non-industry interventional studies with no phase under Dyspnea, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 28. This study's 2 months is below that.
Counting every sponsor, half of 284 studies reached it within 13 months; a quarter within 6 and three quarters within 28.
Since we started tracking on Sep 25, 2026, the dates moved once, on Oct 26, 2026: primary completion Jun 2026 → Jul 2026 and completion Jun 2026 → Jul 2026.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Istanbul Aydın University