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Not yet recruitingNCT07888920Updated Oct 22, 2026

Effects of Visual and Vestibular Rehabilitation in Individuals With Knee Osteoarthritis

An interventional study of Conventional Physiotherapy and Visual Rehabilitation in Knee Osteoarthritis, Visual Rehabilitation and Vestibular Rehabilitation, sponsored by Istanbul Aydın University. Not yet recruiting at 2 sites in Turkey (Türkiye). Open to participants aged 40 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-10-22.

Sponsored by Istanbul Aydın University · Not applicable, Interventional, and Treatment

Updated Oct 22, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
42
Allocation
Randomized
Ages
40 Years to 65 Years
Sex
All
01

Study summary

This study aims to investigate the effects of visual rehabilitation and vestibular rehabilitation added to conventional physiotherapy on postural stability, pain, and functional status in individuals with knee osteoarthritis. Participants will be randomly assigned to three groups: conventional physiotherapy, conventional physiotherapy combined with visual rehabilitation, or conventional physiotherapy combined with vestibular rehabilitation. The study will evaluate changes in balance, pain, and functional performance before and after the intervention.

02

Conditions studied

  • Knee Osteoarthritis
  • Visual Rehabilitation
  • Vestibular Rehabilitation
  • Postural Stability
  • Balance
  • Pain
  • Functional Status
03

In context

Osteoarthritis, Knee

3,391 studies on the registry are indexed under Osteoarthritis, Knee; 628 are open to participants now.

This study's planned enrollment of 42 is below the median of 69 across 2,808 interventional studies indexed under Osteoarthritis, Knee.

Browse Osteoarthritis, Knee studies →

Lead sponsor

Istanbul Aydın University is the lead sponsor of 70 studies on the registry; 20 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
40 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Clinical and radiological diagnosis of knee osteoarthritis.
  2. Kellgren-Lawrence Grade 2-3 knee osteoarthritis.
  3. Age 40-65 years.
  4. Ability to ambulate independently.
  5. Voluntary participation and provision of written informed consent. -

Exclusion criteria

Exclusion Criteria:

  1. Kellgren-Lawrence Grade 4 knee osteoarthritis.
  2. History of lower extremity surgery.
  3. Other orthopedic pathologies accompanying knee osteoarthritis.
  4. History of neurological, vestibular, or central nervous system disease.
  5. Ophthalmological disease that may affect visual perception, visual field, or peripheral vision even with corrected vision (e.g., glaucoma, retinal pathologies, advanced cataract).
  6. Participation in a balance or vestibular rehabilitation program within the previous 6 months.
  7. Systemic disease that would prevent exercise participation (e.g., cardiovascular disease or uncontrolled hypertension).

    -

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
42 participants (estimated)

Study arms

  • Active comparator
    Conventional Physiotherapy

    Participants in this arm will receive conventional physiotherapy, including transcutaneous electrical nerve stimulation (TENS), cold pack application, patellar mobilization, quadriceps isometric exercises, progressive resistance exercises, straight leg raises, and hamstring and gastrocnemius stretching.

    Behavioral: Conventional Physiotherapy

  • Experimental
    Conventional Physiotherapy + Visual Rehabilitation

    Participants in this arm will receive conventional physiotherapy combined with peripheral vision-focused visual rehabilitation.

    Behavioral: Conventional Physiotherapy · Behavioral: Visual Rehabilitation

  • Experimental
    Conventional Physiotherapy + Vestibular Rehabilitation

    Participants in this arm will receive conventional physiotherapy combined with vestibular rehabilitation involving standardized rhythmic head movements.

    Behavioral: Conventional Physiotherapy · Behavioral: Vestibular Rehabilitation

Interventions

  • BehavioralConventional Physiotherapy

    Participants will receive conventional physiotherapy consisting of transcutaneous electrical nerve stimulation (TENS), cold pack application, grade I-II patellar mobilization, quadriceps isometric exercises, progressive resistance exercises, straight leg raises, and static hamstring and gastrocnemius stretching. The intervention will be provided three times per week for six weeks, with a total of 18 sessions.

  • BehavioralVisual Rehabilitation

    Participants will receive conventional physiotherapy combined with peripheral vision-focused visual rehabilitation. Visual rehabilitation will involve peripheral visual stimuli presented using the Smart Optometry Pro application while participants maintain central fixation and respond to the stimuli with motor actions. The intervention will be provided for 20 minutes per session, three times per week for six weeks, for a total of 18 sessions.

  • BehavioralVestibular Rehabilitation

    Participants will receive conventional physiotherapy combined with vestibular rehabilitation involving standardized rhythmic head movements. Head movements will be performed in right-left and anterior-posterior directions at a standardized rhythm using a metronome application. The intervention will be provided for 20 minutes per session, three times per week for six weeks, for a total of 18 sessions.

06

What researchers measure

Primary outcomes

  1. Postural Stability

    Postural stability will be assessed using the Ottometriks Balance Platform. Center of pressure (COP) displacement and postural sway in the anteroposterior and mediolateral directions will be evaluated.

    Time frame: At baseline and immediately after the 6-week intervention

Secondary outcomes

  1. Pain Intensity

    Pain intensity will be assessed using the Short-Form McGill Pain Questionnaire (SF-MPQ).

    Time frame: At baseline and immediately after the 6-week intervention

  2. WOMAC

    Functional status will be assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).

    Time frame: At baseline and immediately after the 6-week intervention

  3. Timed Up and Go Test (TUG)

    Functional mobility will be assessed using the Timed Up and Go Test (TUG).

    Time frame: At baseline and immediately after the 6-week intervention

  4. Y Balance Test

    Dynamic balance will be assessed using the Y Balance Test.

    Time frame: At baseline and immediately after the 6-week intervention

  5. Berg Balance Scale (BBS)

    Balance performance will be assessed using the Berg Balance Scale (BBS).

    Time frame: At baseline and immediately after the 6-week intervention

  6. Peripheral Vision

    Peripheral vision will be assessed using the standardized photo-based assessment method specified in the study protocol.

    Time frame: At baseline and immediately after the 6-week intervention

07

Study locations

2 sites
  • Istanbul Aydin University Medical Park Florya Hospital
    Istanbul, Istanbul 34295, Turkey (Türkiye)
  • Istanbul Aydin University
    Istanbul, Istanbul 34295, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Oct 2026; primary completion for Oct 2026, 0 months later.

Of 1,143 non-industry interventional studies with no phase under Osteoarthritis, Knee, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 36. This study's planned 0 months is below that.

Counting every sponsor, half of 1,285 studies reached it within 18 months; a quarter within 8 and three quarters within 36.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 16, 2026
First posted
Oct 22, 2026
StartEst.
Oct 28, 2026
Primary completionEst.
Oct 30, 2026
CompletionEst.
Apr 1, 2027
Last update
Oct 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 22, 2026
Show all 1 update
  1. Oct 22, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07888920
Lead sponsor
Istanbul Aydın University
Responsible party
Sponsor
First posted
Oct 22, 2026
Start date
Oct 28, 2026 (estimated)
Primary completion
Oct 30, 2026 (estimated)
Completion
Apr 1, 2027 (estimated)
Last update
Oct 22, 2026

Study contacts

Kamer Ünal Eren, PhD
Contact
kamerunaleren@aydin.edu.tr
0544 207 89 42
Kamer Ünal Eren
principal investigator · Istanbul Aydın University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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