ClinicalTrials.gg
RecruitingNCT07332845Updated Mar 10, 2026

Symmetrical Scapula-pelvis Proprioceptive Neuromuscular Facilitation and Superficial Back Line in Chronic Neck Pain With Hamstring Tightness

An interventional study of Suboccipital muscle inhibition technique and Symmetrical Scapula-Pelvis Patterns Exercises in Chronic Neck Pain, Hamstring Muscle Tightness and Neck Pain, sponsored by University of Karachi. Recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-03-10.

Sponsored by University of Karachi · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Jan 2026; still recruiting 9 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
156
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
All
01

Study summary

A research study will be conducted at Physiotherapy department of the Sindh Institute of Physical Medicine and Rehabilitation, Karachi, Pakistan. Overall 156 patients with 18-40 years old individuals with neck pain will be eligible and they will be included through non-probability, purposive sampling technique. The written informed consent will be taken from all the patients. They will be divided through Simple random sampling (computer generated software) method into two groups, 78 in each group. Group A (experimental group) will receive PNF Symmetrical Scapula-Pelvis Patterns (PNF-SSPP), group B (control group) will receive sub occipital muscle inhibition technique (SMI) and static stretching (SS) of hamstring muscle. All participants will be assessed using assessment form. Outcome measures will be Pain, disability, disability, neck range of motions, hamstring tightness, head posture, and levator scapulae index. An independent assessor blinded to the treatment will assess all the patients for treatment outcome assessment at baseline, after first session and post treatment. Treatment sessions will be given thrice a week for 6 weeks.

Read the detailed description

A maximum drop-out rate of 20% is expected. The Statistical package for the social sciences (SPSS) 23 version will be used for data analysing. The Mean ± SD will be calculated for quantitative variables like age. The qualitative variables will be shown through calculated frequencies and percentages. The outcome results of the study (decrease pain intensity, improve disability, improve ROM and improve muscle tightness) taken before, after 1st session and after 18th session will be compared and analyzed. The repeated measure of ANOVA will be used as the statistical test. The p-value of 0.05 will be considered as level of significant.

02

Conditions studied

  • Chronic Neck Pain
  • Hamstring Muscle Tightness
  • Neck Pain

Keywords

  • neck ache
  • Exercise
  • Muscle Stretching
  • Muscle Inhibition
  • PNF
03

In context

Neck Pain

1,360 studies on the registry are indexed under Neck Pain; 299 are open to participants now.

This study's planned enrollment of 156 is above the median of 50 across 1,116 interventional studies indexed under Neck Pain.

Browse Neck Pain studies →

Lead sponsor

University of Karachi is the lead sponsor of 37 studies on the registry; 9 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Individual with both male and female gender
  • Individuals with chronic neck pain (pain for > 3 month) with hamstring tightness

Exclusion criteria

Exclusion Criteria:

  • Any history related to spinal surgery
  • Previous administration of epidural injections
  • Neck pain due to specific pathology
  • Patients with radiculopathy or myelopathy
  • Traumatic spinal cord injury
  • Neck pain associated with progressive neurological deficit or loss of strength
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
156 participants (estimated)

Study arms

  • Experimental
    Symmetrical Scapula-Pelvis Pattern Exercises

    This arm will receive PNF Dynamic Reversal of Antagonists using Symmetrical Scapula-Pelvis Patterns

    Other: Symmetrical Scapula-Pelvis Patterns Exercises

  • Active comparator
    Control Treatment

    This arm will receive evidence based treatment, the suboccipital muscle inhibition with static stretching of the hamstrings.

    Other: Suboccipital muscle inhibition technique · Other: Static stretching of hamstring muscle

Interventions

  • OtherSuboccipital muscle inhibition technique

    The Suboccipital Muscle Inhibition technique is a manual therapy method used by practitioners to relieve tension in the suboccipital muscles, which are located at the base of the skull.

  • OtherSymmetrical Scapula-Pelvis Patterns Exercises

    Symmetrical scapula-pelvis patterns refer to a balanced, aligned posture and movement of the shoulder blades and pelvis which is often a therapeutic goal in physical rehabilitation with proprioceptive neuromuscular facilitation.

  • OtherStatic stretching of hamstring muscle

    Static stretching for hamstrings involves holding a position that creates tension in the back of the thigh for 30 seconds.

06

What researchers measure

Primary outcomes

  1. Change in pain intensity with visual analogue scale for pain at Day 1

    The Visual Analogue Scale is a 10 cm line used to measure pain intensity, where the patient marks a point on the line to indicate their pain level, with 0 representing "no pain" and 10 representing "pain as bad as it could possibly be". A score is obtained by measuring the distance from the "no pain" end to the patient's mark, which can be done in centimeters (0-10) or millimeters (0-100). Higher scores indicate greater pain intensity, and this score helps healthcare providers assess severity, which can be categorized as mild (1-3), moderate (4-6), or severe (7-10)

    Time frame: From enrolment to the end of the first treatment session at Day 1.

  2. Change in pain intensity with visual analogue scale for pain at 6 weeks

    The Visual Analogue Scale (VAS) is a 10 cm line used to measure pain intensity, where the patient marks a point on the line to indicate their pain level, with 0 representing "no pain" and 10 representing "pain as bad as it could possibly be". A score is obtained by measuring the distance from the "no pain" end to the patient's mark, which can be done in centimeters (0-10) or millimeters (0-100). Higher scores indicate greater pain intensity, and this score helps healthcare providers assess severity, which can be categorized as mild (1-3), moderate (4-6), or severe (7-10).

    Time frame: From enrolment to the end of 18 treatment session at 6 weeks

  3. Change in range of motion with goniometry at Day 1

    Goniometry measures the change in range of motion of a joint in degrees by using a goniometer to calculate the joint's angle. The increase in degrees suggests increase in range of motion and decrease suggests decrease in range of motion.

    Time frame: From enrolment to the end of first treatment at Day 1

  4. Change in range of motion with goniometry at 6 weeks

    Goniometry measures the change in range of motion of a joint in degrees by using a goniometer to calculate the joint's angle. The increase in degrees suggests increase in range of motion and decrease suggests decrease in range of motion.

    Time frame: From enrolment to the end of 18 treatment sessions at 6 weeks.

  5. Change in neck disability with Neck Disability Index at day 1

    A change in the Neck Disability Index score indicates a change in a patient's self-reported neck disability. A higher score means greater disability.The NDI is scored from 0 to 50, or 0% to 100%. A score of 0 indicates no limitation, while a score of 50 represents complete limitation.

    Time frame: From enrolment to the end of first treatment session at Day 1.

  6. Change in neck disability with Neck Disability Index at 6 weeks

    A change in the Neck Disability Index score indicates a change in a patient's self-reported neck disability. A higher score means greater disability.The NDI is scored from 0 to 50, or 0% to 100%. A score of 0 indicates no limitation, while a score of 50 represents complete limitation.

    Time frame: From enrolment to the end of 18 treatment sessions at 6 weeks.

  7. Change in hamstring tightness with Sit and Reach (SR) test at Day 1

    A low Sit and Reach test score in centimetre indicates tight hamstrings, while a higher score shows better hamstring flexibility. When a person with tight hamstrings performs the Sit and Reach test, the muscles pull the pelvis into a posterior tilt, which limits the ability to reach as far and can cause the lower back to round instead of the spine flexing naturally. As hamstring tightness decreases through stretching, the SR score increases, signifying greater flexibility and improved superficial back line.

    Time frame: From enrolment to the end of first treatment session at Day 1.

  8. Change in hamstring tightness with Sit and Reach (SR) test at 6 weeks

    A low Sit and Reach test score in centimetre indicates tight hamstrings, while a higher score shows better hamstring flexibility. When a person with tight hamstrings performs the Sit and Reach test, the muscles pull the pelvis into a posterior tilt, which limits the ability to reach as far and can cause the lower back to round instead of the spine flexing naturally. As hamstring tightness decreases through stretching, the SR score increases, signifying greater flexibility and improved superficial back line.

    Time frame: From enrolment to the end of 18 treatment sessions at 6 weeks.

Secondary outcomes

  1. Change in head posture with goniometry at Day 1

    Goniometry can measure changes in forward head posture by using a goniometer to calculate the craniovertebral angle. This involves placing the goniometer's base on the C7 spinous process and the moving arm on the tragus of the ear, with a smaller CVA angle indicating a greater degree of forward head posture and vice versa. Changes are tracked by taking repeated measurements over time to see if the CVA increases (improving posture) or decreases (worsening posture).

    Time frame: From enrolment to the end of first treatment session at Day 1

  2. Change in head posture with goniometry at 6 weeks

    Goniometry can measure changes in forward head posture by using a goniometer to calculate the craniovertebral angle. This involves placing the goniometer's base on the C7 spinous process and the moving arm on the tragus of the ear, with a smaller CVA angle indicating a greater degree of forward head posture and vice versa. Changes are tracked by taking repeated measurements over time to see if the CVA increases (improving posture) or decreases (worsening posture).

    Time frame: From enrolment to the end of 18 treatment sessions at 6 weeks

  3. Change in levator scapulae index with vernier caliper at Day 1

    The levator scapulae index is a measurement technique used to assess the relative length of the levator scapulae muscle. It provides a normalized value by comparing the muscle's length to an individual's total body height, which accounts for variations in size between patients. A vernier caliper is the tool used for this measurement due to its accuracy. A normal levator scapulae index range is greater than or equal to 7.44. Decrease in score suggests decrease in muscle length and increase suggests increase in length.

    Time frame: From enrolment to the end of first treatment session at Day 1

  4. Change in levator scapulae index with vernier caliper at 6 weeks

    The levator scapulae index is a measurement technique used to assess the relative length of the levator scapulae muscle. It provides a normalized value by comparing the muscle's length to an individual's total body height, which accounts for variations in size between patients. A vernier caliper is the tool used for this measurement due to its accuracy. A normal levator scapulae index range is greater than or equal to 7.44. Decrease in score suggests decrease in muscle length and increase suggests increase in length.

    Time frame: Time Frame: From enrolment to the end of 18 treatment sessions at 6 weeks

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jan 2026 (actual). Primary completion is estimated for Oct 2026, 9 months after the start.

Of 763 non-industry interventional studies with no phase under Neck Pain, half reached primary completion within 7 months of starting (the median), counting those still running; a quarter within 3 and three quarters within 15. This study's planned 9 months is above that.

Counting every sponsor, half of 772 studies reached it within 7 months; a quarter within 3 and three quarters within 15.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 30, 2025
First posted
Jan 12, 2026
StartActual
Jan 16, 2026
Primary completionEst.
Oct 26, 2026
CompletionEst.
Nov 26, 2026
Last update
Mar 10, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Mar 10, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07332845
Lead sponsor
University of Karachi
Collaborators
Sindh Institute of Physical Medicine and Rehabilitation
Responsible party
Aftab Ahmed Mirza Baig,DPT, MSAPT (Principal Investigator, University of Karachi) — Principal investigator
First posted
Jan 12, 2026
Start date
Jan 16, 2026
Primary completion
Oct 26, 2026 (estimated)
Completion
Nov 26, 2026 (estimated)
Last update
Mar 10, 2026

Study contacts

Aftab Ahmed Mirza Baig, PhD
Contact
ab.dptrm@gmail.com
+923002739920
Basit Ansari, PhD
Contact
basitansari@hotmail.com
+923222279221
Aftab Ahmed Mirza Baig, PhD
principal investigator · University of Karach
Basit Ansari, PhD
study director · University of Karachi

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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