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Not yet recruitingNCT07264374Updated Dec 4, 2025

Femoral Vein, Internal Jugular Vein and Inferior Vein Cava Collapsibility Indices in Polytrauma Patients by Sonographic Evaluation Before and After Resuscitation.

An observational study in Shock and Hyopvolemia, sponsored by Assiut University. Not yet recruiting at 1 site in Egypt. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2025-12-04.

Sponsored by Assiut University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
50
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The aim of this study is to evaluate correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED by sonographic evaluation before and after resuscitation.

Read the detailed description

Polytrauma patients often present with hemodynamic instability where rapid and accurate assessment of intravascular volume is crucial. Central venous pressure monitoring, though considered a standard, is invasive and not always feasible in emergency settings. Point-of-care ultrasound (POCUS) provides a non-invasive alternative through assessment of venous collapsibility indices.

The inferior vena cava (IVC) collapsibility index is commonly used, but its evaluation may be limited in cases of abdominal trauma, obesity, or technical difficulties. The internal jugular vein (IJV) and femoral vein (FV) are superficial, easily accessible, and may provide reliable alternatives.

This study aims to compare the collapsibility indices of the IVC, IJV, and FV in polytrauma patients before and after resuscitation using sonographic evaluation. The objective is to determine their relative accuracy and feasibility as non-invasive markers of intravascular volume status to guide resuscitation in emergency settings.

02

Conditions studied

  • Shock
  • Hyopvolemia

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03

In context

Shock

487 studies on the registry are indexed under Shock; 107 are open to participants now.

This study's planned enrollment of 50 is below the median of 100 across 247 observational studies indexed under Shock.

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Lead sponsor

Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

The study population will include adult patients aged 18-65 years presenting with shock to the emergency department and requiring volume status assessment through both IVC,FV and IJV collabsibility indecis by ultrasound.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adult patients aged ≥ 18years. ( Patients presented by hypovolemic shock

Exclusion criteria

Exclusion Criteria:

  • Patient refusal > 40 kg/m2. Cardiac patients or cardiac tamponade Aortic injury or for cardio-thoracic emergent operation Patients with abdominal mass or other pathology as abdominal collection. Any patient needs emergent surgical intervention History of pulmonary artery hypertension. Femoral vein occlusion. Pregnancy. Pulmonary oedema. Patients will need mechanical ventilation.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
50 participants (estimated)
Patient registry
No

Interventions

  • DeviceUltrasound assesment of FV,IJV and IVC collabsibillity indecis

    Ultrasound-Guided Inferior Vena Cava,femoral vein and internal jugular vein collabsibilty indecis Assessment This intervention involves bedside ultrasound measurement of the inferior vena cava (IVC) diameter and calculation of the IVC collapsibility/distensibility index. Assessments will be performed both at initial presentation and after fluid resuscitation in shock patients. The procedure is non-invasive, rapid, and performed according to standardized emergency ultrasound protocols.

06

What researchers measure

Primary outcomes

  1. correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients presenting to the ED before and after resuscitation.

    Time frame: correlation between the collapsibility indices of the FV or IJV to IVC-CI among polytrauma patients at time of presentation to the ED and after one hour of resuscitation.

07

Study locations

1 site
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07264374
Lead sponsor
Assiut University
Responsible party
Mahmoud Ahmed Abdelrady Mahmoud (Comparative Study of Femoral vein, Internal jugular vein and Inferior vein cava Collapsibility Indices in polytrauma patients presenting to the emergency department by sonographic evaluation before and after resuscitation, Assiut University) — Principal investigator
First posted
Dec 4, 2025
Start date
Dec 15, 2025 (estimated)
Primary completion
Nov 15, 2026 (estimated)
Completion
Dec 15, 2026 (estimated)
Last update
Dec 4, 2025

Study contacts

Mahmoud Ahmed Abdelrady Mahmoud, M.B.B.Ch
Contact
ammmahmoud1998@gmail.com
20+01013174106
Adel Hamid Elbaih, Professor
Contact
Elbaih.zico@med.suez.edu.eg
20+201104534669

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.

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