An interventional study of standardized evaluation and single IRT session and a minimal blood test in Juvenile Idiopathic Arthritis, Infrared Thermography and Joint Inflammation, sponsored by Centre Hospitalier Universitaire, Amiens. Recruiting at 1 site in France. Open to participants aged 2 Years to 16 Years. Per ClinicalTrials.gov, last updated 2026-11-03.
Sponsored by Centre Hospitalier Universitaire, Amiens · Not applicable, Interventional, and Screening
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children, causing persistent joint inflammation, pain, and functional impairment. Current monitoring relies on clinical scores, laboratory markers, and imaging, which are often resource intensive. Infrared thermography (IRT) is a non-invasive, radiation-free method that detects skin temperature changes potentially reflecting joint inflammation. Evidence in pediatric populations is limited, but IRT could provide an objective, reproducible, and child-friendly tool. This study aims to evaluate IRT's diagnostic accuracy by comparing it with clinical scores, laboratory markers, and ultrasound Doppler, to assess its utility as a complementary monitoring tool.
Patients with JIA will undergo clinical examination, routine blood tests, and IRT at baseline, 1 month, and 3 months. Control patients will participate in a single IRT session and, a CRP/ESR/blood test; if a biological workup is already planned as part of their routine care, existing results will be collected, and no additional sampling will be performed. IRT will follow a standardized protocol, including an acclimatization period, predefined positioning, and acquisition of three consecutive images per joint. After completion of the study, JIA patients will resume their standard-of-care follow-up.
365 studies on the registry are indexed under Arthritis, Juvenile; 101 are open to participants now.
This study's planned enrollment of 60 is above the median of 52 across 230 interventional studies indexed under Arthritis, Juvenile.
Browse Arthritis, Juvenile studies →Centre Hospitalier Universitaire, Amiens is the lead sponsor of 586 studies on the registry; 185 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Autoimmune disease
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: standardized evaluation
Other: single IRT session and a minimal blood test
Patients with JIA will undergo a standardized evaluation including a clinical joint examination, routine blood tests (CRP, NFS, ionogram, liver function, coagulation), and IRT of selected joints
Control patients will undergo a single IRT session and a minimal blood test (CRP, ESP, blood count). IRT will be performed under controlled conditions with a defined joint positioning, 15-30 minutes of acclimatization, and acquisition of three consecutive images per joint.
variation of IRT measure between both groups
variation of IRT measure between both groups
Time frame: at baseline
variation of IRT measure between both groups
variation of IRT measure between both groups
Time frame: at 1 month
variation of IRT measure between both groups
variation of IRT measure between both groups
Time frame: at 3 months
longitudinal changes in thermographic measurements
longitudinal changes in thermographic measurements by comparing temperature differences (ΔT) between baseline (D0) and 3 months
Time frame: at 3 months
correlation of longitudinal changes in thermographic measurements with clinical parameters
Time frame: at 3 months
correlation of longitudinal changes in thermographic measurements with functional parameters
Time frame: at 3 months
correlation of longitudinal changes in thermographic measurements with biological parameters
Time frame: at 3 months
correlation of diagnostic performance of IRT with clinical examination
Time frame: at 3 months
correlation of diagnostic performance of IRT with ultrasounds
Time frame: at 3 months
correlation of diagnostic performance of IRT with MRI
Time frame: at 3 months
reproducibility of IRT measurements
Time frame: at 3 months
Plan to share: No
No publications or documents are linked to this record.
Started Aug 2026 (actual). Primary completion is estimated for Aug 2028, 24 months after the start.
Of 53 non-industry interventional studies with no phase under Arthritis, Juvenile, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 35. This study's planned 24 months is above that.
Counting every sponsor, half of 56 studies reached it within 14 months; a quarter within 8 and three quarters within 39.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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