Craniosynostoses clinical trials
The registry lists 52 studies for Craniosynostoses across more than 10 countries. 14 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.
Status
- Completed
- 22
- Recruiting
- 8
- Not yet recruiting
- 6
- Terminated
- 5
- Withdrawn
- 4
- Active, not recruiting
- 3
Phase
- Phase 4
- 3
- Phase 1
- 1
- Phase 2
- 1
- Phase 3
- 1
Where
- United States
- 23
- France
- 8
- Italy
- 4
- United Kingdom
- 2
- Korea, Republic of
- 2
- Brazil
- 2
Who runs them
Hospices Civils de Lyon (3) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (3) · Assiut University (2) · National Human Genome Research Institute (NHGRI) (2) · Boston Children's Hospital (2) · University of Texas Southwestern Medical Center (2) · University of Pittsburgh (2) · dr. Laura C. G. de Graaff-Herder (1)
Studies
Recruiting first, then most recently updated. Showing 50 of 52 — search for more.
- Frontal Reconstruction Without Orbital Advancement for Moderate Metopic CraniosynostosisNot yet recruitingNCT07837453Not applicable1 country
- Effects of Tummy Time Associated With Therapeutic Positioning in Premature Newborns With Cranial AsymmetryNot yet recruitingNCT07758426Not applicable1 country
- Comparing Conservative to Surgical Treatment of Trigonocephaly Craniofacial Surgery in Children With Trigonocephaly: an Observational Cohort Study on Clinical Outcomes, Psychosocial Wellbeing, and CostsRecruitingNCT060694791 country
- ASO Treatment for Syndromic CraniosynostosesRecruitingNCT075353721 country
- Effectiveness of Repositioning and Cranial Remolding in Infants With Cranial DeformationRecruitingNCT05917678Not applicable1 country
- Pleth Variability Index Monitoring in Pediatric Craniosynostosis SurgeryRecruitingNCT076575981 country
- Multimodal Mechanical, Tissue, Architectural, and Histological Evaluation of the Bone and Sutures of the Parietal Bone in an Infant With Craniosynostosis.Not yet recruitingNCT076509811 country
- Burosumab and 1-25 (OH) Vitamin D on Human OsteoblastsRecruitingNCT041596751 country
- Ocular Characteristics in Patients With CraniosynostosisRecruitingNCT069287271 country
- Hemodynamic Monitoring During Craniosynostosis Surgery: Comparing Traditional and Newer Technology Monitors (CRASY-PRAM)RecruitingNCT062630751 country
- Effects of Corrective Helmet Therapy on Cervical Motion and Thermoregulation in Children With Positional DeformitiesNot yet recruitingNCT07201324
- Cranial Remolding Orthosis RegistryNot yet recruitingNCT067626911 country
- EPBONF : Evaluation of the Safety and Effectiveness of a Medical Device Aimed at Guiding Orbito-naso-frontal Band Surgery, for the Treatment of CraniostenosesNot yet recruitingNCT06366178Not applicable
- GROWing Up With Rare GENEtic SyndromesRecruitingNCT044633161 country
- Monitoring System for Cranial OrthosesCompletedNCT064251721 country
- Neurodevelopmental Outcomes in Craniosynostosis RepairTerminatedNCT04072783Not applicable1 country
- Efficacy of Amicar for Children Having Craniofacial SurgeryActive, not recruitingNCT02229968Phase 21 country
- Qualitative and Quantitative Study Which Aims to Determine the Specifics of the Announcement for the Diagnosis of Patients With Craniosynostosis and Their Parents to Better Support Them in Their CareCompletedNCT022878051 country
- Endoscopic Strip Craniectomy for Treatment of Sagittal CraniosynostosisTerminatedNCT04721769Not applicable1 country
- Comparing MRI to CT on Pediatric Craniosynostosis.CompletedNCT04704284Not applicable1 country
- Functionalized Bioink Delivering Biomolecules for the Treatment of Craniofacial DiseasesActive, not recruitingNCT065331501 country
- Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull BonesActive, not recruitingNCT030257635 countries
- Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the ChildCompletedNCT03231085Not applicable1 country
- Examination of Neuromotor Development of Cases Diagnosed with ScaphocephalyCompletedNCT062946261 country
- Treatment of Cranial Molding Deformities in Preterm InfantsCompletedNCT02366936Not applicable1 country
- CraNIRS Clinical StudyCompletedNCT040860561 country
- Clinical Feasibility Study of Preoperative Surgical PlanningWithdrawnNCT03812159Not applicable1 country
- Bedside Resources to Gauge Intravascular Volume StatusCompletedNCT03915587Not applicable1 country
- MRI for Non-invasive Evaluation of Brain StressCompletedNCT01898650Not applicable1 country
- Craniosynostosis :Surgical Treatment Modalities and OutcomeStatus unknownNCT05511168Not applicable
- Effectiveness of Ottobock Helmet Therapy in Infants With Plagiocephaly, Brachycephaly or Combination of BothCompletedNCT051541751 country
- Investigation of Anthropometric Properties of Babies With CraniosynostosisCompletedNCT048275241 country
- Craniofacial Imaging With 3D MRI: an Alternative to Ionising RadiationStatus unknownNCT04695938Not applicable1 country
- Myelin Imaging Changes In Patients With Neurosurgical DiseasesTerminatedNCT036988381 country
- Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)CompletedNCT001069771 country
- The Efficacy and Population Pharmacokinetics of Tranexamic Acid for Craniosynostosis SurgeryCompletedNCT02188576Phase 41 country
- Scalp Block Decreases Pain and Side EffectsCompletedNCT041334671 country
- Blood Loss and Transfusion Requirement in Infants Treated With Tranexamic AcidSuspendedNCT01094977Phase 31 country
- Osteogenic Profiling of Tissue From Children With CraniosynostosisCompletedNCT00773643Not applicable1 country
- Irradiated Blood Versus Non Irradiated Blood Transfusions in Craniosynostosis RepairCompletedNCT02483702Not applicable1 country
- Optic Nerve Sheath Diameter in CraniosynostosisCompletedNCT031312451 country
- Genetic Analysis of Craniosynostosis, Philadelphia TypeCompletedNCT003677961 country
- Tranexamic Acid for Craniofacial SurgeryTerminatedNCT00722436Phase 41 country
- Cranial Cup Use for the Prevention of Positional Head Shape Deformity in the NICUTerminatedNCT01218087Not applicable1 country
- Comparison of a Bone Product to Bone Dust in Ossification of Small Calvarial Defects.WithdrawnNCT01006148Phase 41 country
- Hanger Helmet StudyWithdrawnNCT02561728Not applicable
- Effect of Tranexamic Acid Based on Pharmacokinetics in Pediatric Patients Undergoing Craniosynostosis Surgery: Randomized Controlled TrialCompletedNCT02180321Not applicable1 country
- Child and Infant Learning ProjectCompletedNCT000778311 country
- Endoscopic Treatment for Isolated, Single Suture CraniosynostosisWithdrawnNCT00769847
- The Effect of Gender on the Consumption of Pain Medication in Infants Undergoing Craniosynostosis Repair or Untethering of Cord in ITUStatus unknownNCT01996163