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Not yet recruitingNCT07889336Updated Oct 22, 2026

Preoperative Nutritional Status and Postoperative Outcomes in Geriatric Lung Resection

An observational study in Thoracotomy, Toracosurgery and Thoracic Anesthesia, sponsored by Ankara Ataturk Sanatorium Training and Research Hospital. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2026-10-22.

Sponsored by Ankara Ataturk Sanatorium Training and Research Hospital · Observational

Updated Oct 22, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
69
Ages
65 Years and older
Sex
All
01

Study summary

Malnutrition is a common comorbidity in patients undergoing thoracic surgery. Furthermore, chronic diseases, polypharmacy, low nutrient intake, reduced appetite, and psychological factors-all frequently observed in geriatric patients-serve as risk factors for the development of nutritional deficiencies. Consequently, it is crucial to address the issue of malnutrition in geriatric patients-who often present with these risk factors-and to ensure that a nutritional status assessment is performed prior to thoracic surgery. While numerous screening tools are currently available to assess nutritional status in the elderly, there is no established "gold standard." Although it has been suggested that these nutritional screening tools can serve as prognostic indicators for geriatric surgical patients, the relationship between these tools and postoperative outcomes-such as pain, complications, and length of hospital stay-has not yet been fully evaluated in geriatric patients undergoing lung resection. This study aims to determine the relationship between preoperative nutritional status and postoperative outcomes in patients undergoing lung resection-an area lacking sufficient literature-and to investigate whether preoperative nutritional support can reduce postoperative complications in this patient population.Patients will undergo preoperative assessment, and data regarding those meeting inclusion criteria will be recorded. This includes routine blood tests, age, height, body weight, BMI, gender, diagnoses, ASA and ARISCAT scores, the surgery performed, durations of surgery/anesthesia/one-lung ventilation, intraoperative fluids and IV agents administered, fluid balance, any complications arising during the procedure or postoperative follow-up (up to discharge), Visual Analog Scale (VAS) scores at postoperative hours 1, 2, 4, 8, 16, and 24, Charlson Comorbidity Index, Clinical Frailty Scale (CFS), and nutritional status (GNRI, NRS-2002, PNI, MNA-SF).

  • Inclusion criteria: Patients undergoing elective thoracic surgery; patients undergoing lung resection via thoracotomy; patients who have provided informed consent; patients over 65 years of age; patients assessed as ASA class 1, 2, or 3; patients with a body mass index (BMI) between 18 and 35.
  • Exclusion criteria: Patients with ASA class IV or higher; patients scheduled for emergency surgery; patients under 65 years of age; patients with a history of prior thoracic surgery; patients in GOLD groups 3 or 4; patients with systemic inflammatory disease; patients with preoperative chronic pain who regularly use anti-inflammatories/analgesics; patients with a history of pulmonary thromboembolism (PTE).
02

Conditions studied

  • Thoracotomy
  • Toracosurgery
  • Thoracic Anesthesia
  • Older Adults (65 Years and Older)
  • Lung Resection Surgery

Keywords

  • thoracotomy
  • older adults(65 years and older)
  • lung resection surgery
  • lung lobectomy
  • pneumonectomy
03

In context

Lead sponsor

Ankara Ataturk Sanatorium Training and Research Hospital is the lead sponsor of 36 studies on the registry; 20 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients undergoing elective thoracic surgery; patients scheduled for lung resection via thoracotomy; patients who have provided informed consent; patients over 65 years of age; patients classified as ASA 1, 2, or 3; patients with a body mass index (BMI) between 18 and 35.

Eligibility criteria

Inclusion criteria: Patients undergoing elective thoracic surgery; patients scheduled for lung resection via thoracotomy; patients who have provided informed consent; patients over 65 years of age; patients classified as ASA 1, 2, or 3; patients with a body mass index (BMI) between 18 and 35.

- Exclusion criteria: Patients classified as ASA IV or higher; patients scheduled for emergency surgery; patients under 65 years of age; patients with a history of prior thoracic surgery; patients in GOLD group 3 or 4; patients with systemic inflammatory disease; patients with preoperative chronic pain who regularly use anti-inflammatory or analgesic medication; patients with a history of pulmonary embolism (PE).

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
69 participants (estimated)
Patient registry
No

Groups and cohorts

  • Patients over the age of 65 who underwent lung resection via thoracotomy.

    Patients over the age of 65 who underwent lung resection via thoracotomy.

06

What researchers measure

Primary outcomes

  1. the correlation between preoperative nutritional status and postoperative results in geriatric patients undergoing lung resection by thoracotomy.

    The primary outcome variable of the study is the evaluation of the correlation between preoperative nutritional status and postoperative outcomes in geriatric patients undergoing lung resection by thoracotomy.Patients will be evaluated preoperatively and patients who meet the inclusion criteria will have routine blood tests, age, height, body weight, BMI, gender, diagnoses, ASA and ARISCAT scores, surgery performed, duration of surgery/anesthesia/single lung ventilation, fluid and iv agents administered intraoperatively, fluid balance, advanced complications, if any, during the procedure or during postoperative follow-up until discharge, postoperative 1., 2., 4., 8., 16. and 24. visual Analog Scale(VAS), Charlson Comorbidity Index, Clinical Frailty Scale(CFS), nutritional status of GNRI, NRS-2002, PNI, MNA-SF and forms will be recorded by filling out

    Time frame: after surgery up to 30 days

Secondary outcomes

  1. comparison of the indicated nutritional risk screening tools in terms of the predictability of postoperative outcomes in geriatric patients who will undergo lung resection with thoracatomy.

    The nutritional screening tools such as nutritional status of GNRI, NRS-2002, PNI, MNA-SF will be compared to determine which one is better at predicting postoperative outcomes.

    Time frame: after surgery up to 30 days

07

Study locations

1 site
  • Ankara Ataturk Sanatoryum Research and Training Hospital
    Ankara, keçiören 06290, Turkey (Türkiye)
08

References and documents

Publications

  • Gunaydin B, Kurtipek O. Elektif Non-Kardiyak Cerrahi Gecirecek Eriskinlerin Pre-Operatif Degerlendirme Kilavuzu: Avrupa Anesteziyoloji Dernegi'nden Guncellenmis Onerilerin Ozeti: Pre-Operative Evaluation of Adults Undergoing Elective Noncardiac Surgery: Summary of the Updated Guideline From the European Society of Anaesthesiology. Turk J Anaesthesiol Reanim. 2019 Jun;47(3):244-272. doi: 10.5152/TJAR.2019.150419. Epub 2018 Jun 1. No abstract available. Turkish. PubMed 31183475 ↗
  • Buja A, De Luca G, Dal Moro S, Mammana M, Zanovello A, Miola S, Boemo DG, Storti I, Bovo P, Zorzetto F, Schiavon M, Rea F. Cost-consequence analysis of the enhanced recovery after surgery protocol in major lung resection with minimally invasive technique (VATS). Front Surg. 2024 Oct 30;11:1471070. doi: 10.3389/fsurg.2024.1471070. eCollection 2024. PubMed 39539512 ↗
  • Le Pimpec Barthes F, Mordant P, Pricopi C, Foucault C, Dujon A, Riquet M. [The place of surgery in metastatic non-small cell lung cancer]. Rev Mal Respir. 2012 Mar;29(3):376-83. doi: 10.1016/j.rmr.2011.07.010. Epub 2012 Feb 22. French. PubMed 22440301 ↗
  • Gao S, Liao X, He Y, Tan Z, Jiang L, Yang J. The effectiveness of multimodal prehabilitation on functional capacity and clinical outcomes in patients undergoing elective laparoscopic colorectal cancer surgery: a systematic review of meta-analysis of randomized controlled trials. J Cancer Surviv. 2026 Mar 24. doi: 10.1007/s11764-026-01978-7. Online ahead of print. PubMed 41872610 ↗
  • Hunter JM. Postoperative pulmonary complications and reversal agents. Br J Anaesth. 2018 Mar;120(3):604. doi: 10.1016/j.bja.2017.12.024. Epub 2018 Jan 17. No abstract available. PubMed 29452820 ↗

Individual participant data

Plan to share: No

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Nov 2026; primary completion for Oct 2027, 11 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 16, 2026
First posted
Oct 22, 2026
StartEst.
Nov 30, 2026
Primary completionEst.
Oct 30, 2027
CompletionEst.
Dec 30, 2027
Last update
Oct 22, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 22, 2026
Show all 1 update
  1. Oct 22, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07889336
Lead sponsor
Ankara Ataturk Sanatorium Training and Research Hospital
Responsible party
Abdullah TAŞDİZEN (Medical doctor, Ankara Ataturk Sanatorium Training and Research Hospital) — Principal investigator
First posted
Oct 22, 2026
Start date
Nov 30, 2026 (estimated)
Primary completion
Oct 30, 2027 (estimated)
Completion
Dec 30, 2027 (estimated)
Last update
Oct 22, 2026

Study contacts

abdullah TAŞDİZEN, MD
Contact
abtasdizen@gmail.com
+90 507 053 48 49

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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