An observational study in Respiratory Distress Syndrome, Newborn and Neonatal Respiratory Distress, sponsored by Assiut University. Not yet recruiting. Open to participants aged Up to 24 Hours. Per ClinicalTrials.gov, last updated 2026-10-05.
Sponsored by Assiut University · Observational
This cross-sectional study aims to evaluate the diagnostic accuracy of chest ultrasound in the diagnosis of respiratory distress syndrome among preterm neonates in comparison with chest X-ray.
Neonatal respiratory distress syndrome is a major cause of morbidity in preterm infants. Chest X-ray is traditionally used for diagnosis but involves ionizing radiation. Lung ultrasound is a bedside, radiation-free alternative.
This observational study will include preterm neonates (≤35 weeks of gestation) presenting with clinical respiratory distress within the first 24 hours of life. Chest ultrasound and chest X-ray findings will be compared to assess diagnostic performance.
1,179 studies on the registry are indexed under Respiratory Distress Syndrome, Newborn; 161 are open to participants now.
This study's planned enrollment of 82 is below the median of 100 across 388 observational studies indexed under Respiratory Distress Syndrome, Newborn.
Browse Respiratory Distress Syndrome, Newborn studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Preterm neonates (≤35 weeks of gestation) with clinical respiratory distress presenting at Assiut University Children's Hospital.
Exclusion Criteria:
Preterm neonates (≤35 weeks of gestation) presenting with clinical and radiographic signs of respiratory distress syndrome within the first 24 hours of life who will undergo both chest ultrasound and chest X-ray.
Sensitivity of chest ultrasound for diagnosis of respiratory distress syndrome
Sensitivity of chest ultrasound for the diagnosis of respiratory distress syndrome in preterm neonates, using chest X-ray as the reference standard.
Time frame: Baseline
Specificity of chest ultrasound
Specificity of chest ultrasound for the diagnosis of respiratory distress syndrome.
Time frame: Baseline
Positive predictive value of chest ultrasound
Positive predictive value of chest ultrasound for the diagnosis of respiratory distress syndrome.
Time frame: Baseline
Negative predictive value of chest ultrasound
Negative predictive value of chest ultrasound for the diagnosis of respiratory distress syndrome.
Time frame: Baseline
Overall diagnostic accuracy of chest ultrasound
Overall diagnostic accuracy of chest ultrasound for diagnosis of respiratory distress syndrome calculated as (true positives + true negatives) divided by total cases, using chest X-ray as reference standard.
Time frame: Baseline
Proportion of neonates with white lung appearance on ultrasound
Proportion of preterm neonates showing white lung appearance on chest ultrasound.
Time frame: Baseline
Proportion of neonates with abnormal pleural line on ultrasound
Proportion of preterm neonates showing abnormal or irregular pleural line on chest ultrasound.
Time frame: Baseline
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Respiratory Distress Syndrome, Newborn→
Assiut University