A Phase 1 interventional study of nano chitosan in Tooth Discoloration, sponsored by Misr University for Science and Technology. Enrolling by invitation at 1 site in Egypt. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-09-25.
Sponsored by Misr University for Science and Technology · Phase 1, Interventional, and Treatment
Among 15 studies in Tooth Discoloration with a site in Egypt — 4 open to participants now, 6 under way, none of them phase 3. Tooth Discoloration · Egypt.
Among the 15 studies in Tooth Discoloration with a site in Egypt, this one is the 5th largest by planned enrollment, is one of 3 that started in 2025, is one of 2 in phase 1, and was the 10th registered.
105 studies on the registry are indexed under Tooth Discoloration; 19 are open to participants now.
This study's planned enrollment of 42 is below the median of 48 across 97 interventional studies indexed under Tooth Discoloration.
Browse Tooth Discoloration studies →4 of the 15 studies in Tooth Discoloration with a site in Egypt are open now, in 1 country. Each count lists the studies.
Of the 8 Tooth Discoloration studies recruiting now, 1 (13%) set no upper age limit and 7 (88%) stop at 75 or younger; 2 take children under 18; 4 take healthy volunteers.
This study: 18 Years to 40 Years · all sexes · healthy volunteers too.
The full table on the hub →15 studies; the count open now beside each. This study's row is marked.
First in 2017; this study’s year is marked. 3 started in 2025.
Median enrollment 20 across the 15 interventional studies. Of the 7 that completed or were terminated, 0 (0%) have results posted.
None of the 15 has an industry lead sponsor. The 6 most frequent:
Misr University for Science and Technology is the lead sponsor of 38 studies on the registry; 15 are open to participants now.
Misr University for Science and Technology has 3 studies filed under Tooth Discoloration — fewer than ten, so there is no comparison to draw.
2 of the studies in Tooth Discoloration with a site in Egypt that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07818031Minia UniversityPeroxide Versus Non-Peroxide In-Office Tooth Bleaching | 2027-02-15 |
| NCT07691658Tanta UniversityClinical Evaluation of Prefabricated Versus 3D-Printed Composite Resin Veneers: in Vivo Study | 2027-04-26 |
Among the 15 studies in Tooth Discoloration with a site in Egypt, from their registry updates:
The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.
The discoloration of teeth might be intrinsic, extrinsic, or combined. A variety of commercial bleaching agents is available. The most common substances used are carbamide peroxide or hydrogen peroxide or a mixture of sodium perborate and hydrogen peroxide.
The aim of the study is to assess the effectiveness of two different in-office bleaching materials carbamide peroxide alone and carbamide peroxide with Chitosan nanoparticles Using diode laser as an activator Regarding tooth whitening and color stability 1 Day , 1 weeks, 1 month after treatment using Vita easy shade.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
peroxides and sodium perborate + 980nm diode laser.
Drug: nano chitosan
nano chitosan
Color change
these assessments were performed for 1 day, 1 week, and 1 month after treatment with Vita easy shade obtaining difference ∆E\* values using colorcoordinates CIE L\*, a\* and b\*
Time frame: these assessments were performed for 1 day, 1 week, and 1 month after treatment with Vita easy shade.
color change using digital vita easy shade guide
color change using digital vita easy shade guide
Time frame: 1 day , 1 week , 1 month
Start is estimated for Oct 2025; primary completion for Oct 2025, 0 months later.
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Misr University for Science and Technology