CClinicalTrials.gg
Not yet recruitingNCT07730658Updated Jul 28, 2026

Comparison of Erythritol Air-Polishing and Conventional Polishing Following Ultrasonic Scaling on the Relapse of Chromogenic Tooth Staining in Children

An interventional study of Guided Biofilm Therapy with erythritol and Conventional Polishing in Black Staining, sponsored by Marmara University. Not yet recruiting at 1 site in Turkey (Türkiye). Open to participants aged 4 Years to 13 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-28.

Sponsored by Marmara University · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
56
Allocation
Randomized
Ages
4 Years to 13 Years
Sex
All
01

Study summary

The goal of this randomized clinical trial is to compare the effect of erythritol air-polishing and conventional polishing following ultrasonic scaling on the relapse of chromogenic tooth staining in children aged 4-13 years attending the Pediatric Dentistry Clinic of Marmara University Faculty of Dentistry for routine dental examination.

The main questions this study aims to answer are:

  • Does erythritol air-polishing reduce the relapse of chromogenic tooth staining compared with conventional polishing following ultrasonic scaling?
  • Is there a difference in the time to relapse of chromogenic tooth staining between the two polishing techniques?

Researchers will compare conventional polishing (prophylaxis paste and a polishing brush) following ultrasonic scaling with erythritol air-polishing performed using the EMS air-polishing device following ultrasonic scaling to determine whether one method is more effective in preventing or delaying the relapse of chromogenic tooth staining.

Read the detailed description

Participants will:

Undergo a routine oral examination. Receive professional removal of chromogenic tooth staining using ultrasonic scaling.

Be randomly assigned to receive either conventional polishing with prophylaxis paste and a polishing brush or erythritol air-polishing using the EMS air-polishing device.

Attend follow-up visits to assess the recurrence of chromogenic tooth staining over time.

Chromogenic tooth staining will be assessed using the Qraycam.

02

Conditions studied

  • Black Staining

Browse trials for

Keywords

  • guided biofilm therapy
  • polishing
  • tooth discoloration
  • air polishing
  • ultrasonic scaling
03

Who can participate

Ages eligible
4 Years to 13 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Children aged 4-13 years.
  • Absence of oral diseases, including gingivitis and oral mucosal diseases.
  • No orthodontic appliances.
  • No history of iron supplementation or professional fluoride treatment within the previous 3 months.
  • Systemically healthy children.

Exclusion criteria

Exclusion Criteria:

  • Presence of oral diseases, including periodontitis, salivary gland diseases, or oral mucosal diseases.
  • History of autoimmune disease.
  • Antibiotic use within the previous 3 months.
  • Consumption of tannin-containing beverages (e.g., tea, coffee, or similar beverages) within the previous 1 month.
04

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
56 participants (estimated)

Study arms

  • Active comparator
    Group 1 (Erythritol Air-Polishing Using the EMS Air-Polishing Device)

    Device: Guided Biofilm Therapy with erythritol

  • Active comparator
    Group 2 (Conventional Polishing Using Prophylaxis Paste and a Polishing Brush)

    Device: Conventional Polishing

Interventions

  • DeviceGuided Biofilm Therapy with erythritol

    Description: Participants assigned to Group 1 will receive professional removal of chromogenic tooth staining using ultrasonic scaling followed by erythritol air-polishing with the EMS air-polishing device, guided by a plaque-disclosing agent. At the end of the procedure, the investigator will record the treatment time, apply the plaque-disclosing agent, obtain intraoral photographs, and assess chromogenic tooth staining using the Qraycam.

  • DeviceConventional Polishing

    Participants will undergo professional tooth cleaning using the ultrasonic scaler of the EMS device. The tooth surfaces will then be polished using a polishing brush and prophylaxis paste.

05

What researchers measure

Primary outcomes

  1. Black Stain Score

    Black Stain Classification (Gasparetto et al., 2003) Score Description Clinical Characteristics 0 None No black pigmentation on the tooth surface. 1. Mild Pigmented dots or thin pigmented lines parallel to the gingival margin that are not continuous. 2. Moderate Continuous pigmented lines o extending over up to one-half of the cervical third of the tooth surface. 3. Severe Pigmentation extending over more than one-half of the cervical third of the tooth surface. Black Stain Classification (Zerman et al., 2024) Score Description A Pigmented lines or dots present only on the buccal surface. B Pigmented lines or dots present on both the buccal and lingual surfaces. C Pigmented lines or dots associated with dental caries. D Recurrent pigmented lines or dots.

    Time frame: Baseline, immediately after polishing, 1 month, 2 months, 3 months, and 6 months

  2. Participant Feedback

    Pain perception during the procedure will be assessed using the Wong-Baker FACES Pain Rating Scale. The scale ranges from 0 to 10, where 0 indicates "no pain" and 10 indicates "hurts worst." Higher scores indicate greater pain intensity (worse outcome).

    Time frame: Periprocedural

  3. Time Session

    The duration of treatment is noted and compared between groups

    Time frame: Periprocedural

06

Study locations

1 site
  • Marmara Üniversitesi Recep Tayyip Erdoğan Külliyesi Sağlık Yerleşkesi, Diş Hekimliği Fakültesi
    Istanbul, MALTEPE 34854, Turkey (Türkiye)
07

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07730658
Lead sponsor
Marmara University
Responsible party
Sponsor
First posted
Jul 28, 2026
Start date
Jul 7, 2026 (estimated)
Primary completion
Jan 1, 2028 (estimated)
Completion
Feb 28, 2028 (estimated)
Last update
Jul 28, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion