An expanded access record providing Peripheral blood sampling in Tension-Type Headache, Unspecified, Intractable, sponsored by University of Gaziantep. Available at 2 sites in Turkey. Open to participants aged 17 Years to 82 Years. Per ClinicalTrials.gov, last updated 2024-08-20.
Sponsored by University of Gaziantep · Expanded access
Tension-type headache (TTH) refers to pain radiating from the forehead to the back of the head as a bilateral band. It often occurs without warning and spreads to the neck muscles. Patients describe it as tension, pressure, or dull pain. It is usually triggered by stress. The complexity of the processes is the biggest difficulty in diagnosing and treating TTH. Although there are genetic connections, there are no single responsible genes.
130 TTH patients and 117 healthy controls were included in the study. Serum markers of the patients were measured. WNT5A, responsible for the Wnt-B catenin signaling pathway, and its receptor FZD3 were examined in the pathogenesis of TTH. Expression changes and methylation profiles of genes were obtained. Genetic and serum parameters were compared. Diagnostic powers were determined by ROC analyses.
144 studies on the registry are indexed under Tension-Type Headache; 41 are open to participants now.
Browse Tension-Type Headache studies →University of Gaziantep is the lead sponsor of 100 studies on the registry; 26 are open to participants now.
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University of Gaziantep