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CompletedNCT05634993Updated Feb 7, 2025

Disability Level and Trunk Control in Individuals With Multiple Sclerosis

An observational study in Multiple Sclerosis, sponsored by Hacettepe University. Completed at 1 site in Turkey. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-02-07.

Sponsored by Hacettepe University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
102
Ages
18 Years to 65 Years
Sex
All
01

Study summary

Trunk control disorders are frequently encountered in individuals with MS. Trunk control is very important for safe and quality movement. Impairment of trunk control reduces the level of independence of individuals during activities of daily living. For this reason, it is extremely important to evaluate the trunk in the examination and treatment of individuals. When the literature was examined, it was seen that studies examining trunk control were insufficient. Therefore, our study was planned to investigate the relationship between disability level and trunk control in individuals with MS.

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Conditions studied

  • Multiple Sclerosis

Keywords

  • multiple sclerosis
  • disability level
  • trunk control
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In context

Multiple Sclerosis

3,460 studies on the registry are indexed under Multiple Sclerosis; 661 are open to participants now.

This study's enrollment of 102 is close to the median of 100 across 1,016 observational studies indexed under Multiple Sclerosis.

Browse Multiple Sclerosis studies →

Lead sponsor

Hacettepe University is the lead sponsor of 983 studies on the registry; 212 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

The population of the study will consist of patients who applied to the Neurology Outpatient Clinic for outpatient treatment and were diagnosed with Multiple Sclerosis by a neurologist and volunteered to participate in the study.

Inclusion criteria

  • Being between the ages of 18-65
  • Having a definite diagnosis of MS
  • Expanded Disability Status Scale (EDSS) score of 8.5 and below
  • Not having an attack in the last 3 months

Exclusion criteria

Exclusion Criteria:

  • Having another musculoskeletal, cardiovascular, pulmonary, metabolic, or neurological disease severe enough to preclude participation in the study.
  • Having severe vision and hearing problems
  • The presence of severe cognitive impairment detected by the physician at a level that prevents the tests from being performed.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
102 participants (actual)
Patient registry
No

Groups and cohorts

  • MS Group

    Other: Assessment

Interventions

  • OtherAssessment

    Assessment of disability level and trunk control

06

What researchers measure

Primary outcomes

  1. Expanded Disability Status Scale

    It is used for the follow-up of neurological disability and disease stage in MS patients. A score of 0 on the scale indicates normal neurological status, while a score of 10 means death due to MS. The higher the score, the higher the disability level.

    Time frame: baseline

  2. Trunk Impairment Scale

    This scale; It consists of 3 sub-headings: static sitting balance, dynamic sitting balance and coordination. The lowest score that can be obtained from the scale is 0, and the highest score is 23. The higher the score, the higher the trunk control.

    Time frame: baseline

  3. "Sit-ups" test

    This test is used to evaluate the strength of the core stability muscles. Individuals are asked to flex the trunk while the knees are flexed in the supine position. The number of repetitions they can do for 30 seconds is recorded.

    Time frame: baseline

  4. Modified "Push-ups" test

    This test is used to evaluate the strength of the core stability muscles. Individuals are asked to raise their body up by extending their elbows while in the prone position. The number of repetitions they can do for 30 seconds is recorded.

    Time frame: baseline

  5. Lateral bridge test

    This test is used to evaluate the endurance of the core stability muscles. Individuals are asked to lift their bodies on their forearms and toes in the side-lying position and maintain this position. The time held in the position is recorded. The test is done separately for the right and left sides.

    Time frame: baseline

  6. Modified "Biering-Sorensen" trunk extension test

    This test is used to evaluate the endurance of the core stability muscles. In the prone position, individuals are asked to hang their upper body over the edge of the bed and slightly extend them while their ankles are supported. The time held in the position is recorded.

    Time frame: baseline

  7. Trunk flexion test

    This test is used to evaluate the endurance of the core stability muscles. Individuals are asked to stand with their torso at 60º with the floor, and their knees and hips at 90º. The time held in the position is recorded.

    Time frame: baseline

  8. "Prone Bridge" test

    This test is used to evaluate the endurance of the core stability muscles.Individuals are asked to lift their torso up in the prone position while the elbows are flexed, carrying their body weight on their forearms and toes. The time held in the position is recorded.

    Time frame: baseline

07

Study locations

1 site
  • Melike Sumeyye Ozen
    Bandırma, Balıkesir, Turkey
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 7, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT05634993
Lead sponsor
Hacettepe University
Collaborators
Bandırma Onyedi Eylül University
Responsible party
Melike Sumeyye Ozen (Research Assistant, Hacettepe University) — Principal investigator
First posted
Dec 2, 2022
Start date
Jun 1, 2022
Primary completion
Jun 1, 2023
Completion
Sep 1, 2023
Last update
Feb 7, 2025

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2025. You cannot join it, but the record below documents what was studied.

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