Sclerosis clinical trials
The registry lists 3,139 studies for Sclerosis across more than 10 countries. 333 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.
Status
- Completed
- 1,924
- Status unknown
- 416
- Terminated
- 275
- Recruiting
- 221
- Withdrawn
- 108
- Not yet recruiting
- 91
Phase
- Phase 2
- 642
- Phase 3
- 351
- Phase 1
- 301
- Phase 4
- 184
- Early Phase 1
- 34
Where
- United States
- 1,154
- France
- 364
- Germany
- 311
- Italy
- 304
- Canada
- 298
- United Kingdom
- 284
Who runs them
Biogen (137) · Novartis Pharmaceuticals (68) · Merck KGaA, Darmstadt, Germany (52) · Bayer (40) · Assistance Publique - Hôpitaux de Paris (31) · National Institute of Neurological Disorders and Stroke (NINDS) (29) · Johns Hopkins University (27) · Charite University, Berlin, Germany (26)
Studies
Recruiting first, then most recently updated. Showing 50 of 3,139 — search for more.
- Study of Diosmin for the Treatment of Digital Ulcers in Systemic SclerosisRecruitingNCT06256575Not applicable1 country
- A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune DiseasesRecruitingNCT07115745Phase 110 countries
- A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)RecruitingNCT06619561Phase 21 country
- Physiological Effects of N-Acetyl Cysteine in Patients With Multiple SclerosisEnrolling by invitationNCT03032601Not applicable1 country
- Screening for Cognitive Disorders in Multiple SclerosisNot yet recruitingNCT070300361 country
- RAPA-501 Therapy for ALSRecruitingNCT04220190Phase 2/31 country
- Fatigue in Multiple Sclerosis and Its Relationship to Inflammatory and Neurodegenerative Markers of the DiseaseEnrolling by invitationNCT070251221 country
- Feasibility of a Vocational Rehabilitation Intervention for Job Retention in Workers With MS-RiaLSM Intervention ProjectRecruitingNCT06805318Not applicable1 country
- Reliability and Validity of the Turkish Version of General Sleep Disturbance Scale (GSDS-T) in Multiple SclerosisRecruitingNCT068759081 country
- PPI Refractory - GERD Mechanisms in Systemic SclerosisNot yet recruitingNCT07022912
- At-home Treatment With Cortico-spinal tDCS for Amyotrophic Lateral SclerosisRecruitingNCT07006571Not applicable1 country
- Dry Needling in Multiple SclerosisRecruitingNCT06394310Not applicable1 country
- The Effect of Physical Activity Levels on Dysmenorrhea Severity, Menstrual Symptoms, and Functional and Emotional Status in Women Diagnosed With Multiple SclerosisEnrolling by invitationNCT070118751 country
- Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple SclerosisRecruitingNCT06890923Phase 21 country
- Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS PatientsAvailableNCT068023281 country
- Systems Biology of Amyotrophic Lateral Sclerosis (ALS)Not yet recruitingNCT07007390
- UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External DevicesRecruitingNCT06992596Not applicable1 country
- Cladribine Tablets as an Exit Therapy StrategyNot yet recruitingNCT068874261 country
- Autologous Hematopoietic Stem Cell Transplantation for Refractory Multiple SclerosisNot yet recruitingNCT06228781Not applicable
- tdCS Combined With Treadmill Training in Patients With Multiple SclerosisRecruitingNCT06986278Not applicable1 country
- Feasibility Study of a Relapse Investigation Questionnaire Administered by an MS Care Coordinator Nurse in Patients With Multiple SclerosisNot yet recruitingNCT069940261 country
- Transcranial Electrical Stimulation in Multiple SclerosisNot yet recruitingNCT06966128Not applicable1 country
- Effect of a Mobile Health App on Pain and Quality of Life in Patients With Neuropathic Pain in Multiple SclerosisNot yet recruitingNCT06982742Not applicable1 country
- Retinal Neuro-vascular Coupling in Patients With Multiple SclerosisRecruitingNCT03401879Not applicable1 country
- Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)Not yet recruitingNCT06973629Phase 31 country
- FIT-ATOMIC Exercise Feasibility TrialNot yet recruitingNCT06870968Not applicable2 countries
- Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection.Not yet recruitingNCT06982534Early Phase 11 country
- Development of Targeted RNA-Seq for Amyotrophic Lateral Sclerosis DiagnosisRecruitingNCT060835841 country
- Effects of Torso Weighting on Muscle Activation During Balance Tests in Individuals With and Without Multiple SclerosisRecruitingNCT06981013Not applicable1 country
- Holter of Movement in Patients With Amyotrophic Lateral Sclerosis.RecruitingNCT062280012 countries
- Early Identification of Brain Lesions in Multiple Sclerosis With Phase Sensitive Inversion Recovery MRIRecruitingNCT069558321 country
- Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple SclerosisEnrolling by invitationNCT057062201 country
- Swiss Multiple Sclerosis RegistryRecruitingNCT029806401 country
- Contribution of Diaphragmatic Ultrasound for Monitoring Diaphragmatic Function in Patients With Amyotrophic Lateral SclerosisRecruitingNCT053529581 country
- Optimising Access to Vocational Rehabilitation for People With Multiple SclerosisNot yet recruitingNCT06966115Not applicable1 country
- Examining the Effect of Mandala Art Therapy on Symptoms and Quality of Life in Multiple Sclerosis PatientsEnrolling by invitationNCT06955962Not applicable1 country
- Cognitive Rehabilitation of Deficits in Patients With Multiple SclerosisRecruitingNCT06964581Not applicable1 country
- Study of NG01 Cell Therapy in Secondary Progressive Multiple SclerosisNot yet recruitingNCT06961383Phase 22 countries
- Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)RecruitingNCT05892614Phase 21 country
- Biomarker-driven Phenotypic Dissection of Amyotrophic Lateral SclerosisRecruitingNCT063185981 country
- The Study Evaluating the Improvement of Nutritional Status and Frailty With Silkworm Pupa Powder Among Patients With Motor Neuron DiseaseRecruitingNCT06765499Not applicable1 country
- Illuminating New Paths in the Treatment of Multiple Sclerosis Relapses - Early and Specialized RehabilitationRecruitingNCT06956326Phase 21 country
- Administration of Fingolimod in Greek Patients With Multiple Sclerosis.Not yet recruitingNCT06949956
- Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy VolunteersRecruitingNCT05395624Phase 1/21 country
- Effect of Dual-Task Training and Cognitive Rehabilitation in Individuals With Multiple Sclerosis.RecruitingNCT06949696Not applicable1 country
- Smart Monitoring Assessing Spasticity-related HealthRecruitingNCT069377231 country
- Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With MethotrexateRecruitingNCT06936215Phase 31 country
- Swiss Multiple Sclerosis Cohort-StudyRecruitingNCT024330281 country
- A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALSRecruitingNCT069179241 country
- Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell IV Infusion for Systemic SclerosisRecruitingNCT05016804Phase 12 countries