An observational study in Precocious Puberty, Early Puberty and Refraction Error, sponsored by Isfahan University of Medical Sciences. Status unknown at 2 sites in Iran, Islamic Republic of. Open to participants aged 4 Years to 11 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-04-21.
Sponsored by Isfahan University of Medical Sciences · Observational
Body size and eye function play an essential role in adapting to the environment and human survival. Growth hormone is commonly recognized by its effect on the height of individuals; Although from an evolutionary perspective, the effects of growth hormone on eye development are more important. Although the effect of growth hormone on eye development has not been accurately determined, the results of a number of studies suggest the effect of growth hormone on eye development.
Despite the large number of studies that have investigated the effects of growth hormone on height growth, there are few studies that have investigated the effects of growth hormone on the eye.
To the best of our knowledge, no study has been conducted to investigate the effect of growth hormone on ocular findings of patients with early or precocious puberty. Therefore, we intend to investigate the effect of growth hormone on ocular findings of patients with early or precocious puberty.
Investigators will achieve the following data from the participants:
4- Stage of puberty
5- Ocular examination
413 studies on the registry are indexed under Refractive Errors; 62 are open to participants now.
This study's planned enrollment of 90 is below the median of 150 across 107 observational studies indexed under Refractive Errors.
Browse Refractive Errors studies →Isfahan University of Medical Sciences is the lead sponsor of 145 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The study groups are children with early or precocious puberty referred to endocrine clinic of Imam Hossein Hospital in Isfahan, Iran. The control group will be selected from the children who visit at the health centers for routine examinations.
Sample group (with early or precocious puberty):
Exclusion Criteria:
Children with early or precocious puberty who receive exogenous growth hormone
Children with early or precocious puberty who does not receive exogenous growth hormone
Healthy children without any past medical history
Refraction Error
Comparison of the refraction error between the study groups
Time frame: 6 months
Axial Length
Comparison of the axial length between the study groups
Time frame: 6 months
Papillitis
Comparison of the frequency of papillitis between the study groups
Time frame: 6 months
Central Corneal Thickness
Comparison of the mean central corneal thickness between the study groups
Time frame: 6 months
This study is status unknown, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.
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Isfahan University of Medical Sciences