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Not yet recruitingNCT06991933Updated May 28, 2025

Construction and Educational Impact of Plastination Models of the Limbic System, Basal Nuclei, Cerebellum, and Human Spinal Cord

An interventional study of Plastination Model Group and Traditional Methods Group in Education, Education, Medical and Education, Medical, Undergraduate, sponsored by Isfahan University of Medical Sciences. Not yet recruiting. Per ClinicalTrials.gov, last updated 2025-05-28.

Sponsored by Isfahan University of Medical Sciences · Not applicable, Interventional, and Basic science

From the registry’s dates

  • Primary completion was expected by Dec 2025, 10 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Sex
All
01

Study summary

Purpose:

This educational trial aims to assess whether plastination models for neuroanatomy training (limbic system, basal ganglia, cerebellum, spinal cord)" improve medical students' understanding of central nervous system anatomy compared to traditional educational methods. It will also evaluate student satisfaction with this teaching tool.

Key Questions:

  1. Do plastination models for neuroanatomy training (limbic system, basal ganglia, cerebellum, spinal cord) enhance test scores in neuroanatomy examinations?
  2. How do students perceive the educational value of these models?

Study Design:

Researchers will compare two teaching methods:

  • Intervention group: Learns using plastination models for neuroanatomy training (limbic system, basal ganglia, cerebellum, spinal cord)
  • Control group: Learns using standard 2D atlases, power point and plastic models

Participants will:

  1. Complete a pre-intervention anatomy knowledge test
  2. Attend 4 weekly neuroanatomy sessions using their assigned method
  3. Take a post-intervention exam and satisfaction survey
  4. Participate in focus groups about their learning experience
02

Conditions studied

  • Education
  • Education, Medical
  • Education, Medical, Undergraduate

Keywords

  • Medical education
  • Neuroanatomy
  • plastination model
03

In context

Lead sponsor

Isfahan University of Medical Sciences is the lead sponsor of 150 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Medical students in their third semester of training
  • Currently enrolled in neuroanatomy coursework at Isfahan University of Medical Sciences
  • No prior formal training with plastinated models
  • Willing to attend all study sessions for 7 weeks
  • Able to complete assessments in persian

Exclusion criteria

Exclusion Criteria:

  • Prior experience with plastinated models
  • Currently taking neuroanatomy remediation courses
  • Planned absences during >20% of study sessions
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    Arm 1 : Plastination Model Group

    Receives instruction using plastinated models of: * Brainstem * Limbic system * Basal ganglia * Cerebellum * Spinal cord Duration: 7 weeks of training (2 hours/week) Taught by professor who every year teaches neuroanatomy Assessment: Standardized anatomy exams + spatial reasoning tests

    Behavioral: Plastination Model Group

  • Active comparator
    Traditional Methods Group

    Receives equivalent instruction using: * Standard textbook and 2D atlases (e.g., Netter's) * Lectures with 2D projections Matched in duration and instructor expertise Same assessment protocol as an experimental group

    Behavioral: Traditional Methods Group

Interventions

  • BehavioralPlastination Model Group

    Model Specifications: "S10 silicone plastination models of brainstem structures (1:1 scale) with: • Sectioned at 2mm intervals to reveal internal architecture

  • BehavioralTraditional Methods Group

    1. Netter's Atlas of Human Anatomy (9th ed.) 2. Standardized PowerPoint lectures

06

What researchers measure

Primary outcomes

  1. Change in neuroanatomy knowledge scores assessed by the "Neuroanatomy Knowledge Assessment Test

    Scale Title: Neuroanatomy Knowledge Assessment Test (NKAT). Score Range: 0 (no correct answers) to 15 (all answers correct). Interpretation: Higher scores indicate better neuroanatomy knowledge (better outcome).

    Time frame: Baseline, Week 4 post-intervention

Secondary outcomes

  1. Spatial understanding assessment

    Method: 3D spatial reasoning test (modified Vandenberg scale) Scoring: 1-5 Likert scale for structure identification accuracy

    Time frame: Post-intervention only

  2. Student satisfaction assessed by the 10-item Student Satisfaction Survey (SSS)

    * Score Range: 1 (strongly disagree) to 5 (strongly agree). * Interpretation: Higher scores indicate greater satisfaction (better outcome).

    Time frame: Immediately after the intervention (Day 1)

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Oct 2025; primary completion for Dec 2025, 2 months later.

How these figures are worked out, and which studies are left out of them.

Registered
May 10, 2025
First posted
May 28, 2025
StartEst.
Oct 23, 2025
Primary completionEst.
Dec 29, 2025
CompletionEst.
Jan 20, 2026
Last update
May 28, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 28, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT06991933
Responsible party
mehrnoush malekzadeh (Assistant Professor, Isfahan University of Medical Sciences) — Principal investigator
First posted
May 28, 2025
Start date
Oct 23, 2025 (estimated)
Primary completion
Dec 29, 2025 (estimated)
Completion
Jan 20, 2026 (estimated)
Last update
May 28, 2025

Study contacts

Mehrnoush Malekzadeh, Ph.D
Contact
mehrnoush.malekzadeh@med.mui.ac.ir
09133097258

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.

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Discussion

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