An observational study in Ischemic Heart Disease, Angina Pectoris and Chest Pain, sponsored by Laval University. Status unknown at 1 site in Canada. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-01-31.
Sponsored by Laval University · Observational
Despite optimal angiographic result after stent implantation, a number of patients will undergo repeat angiography within 1 year of index procedure. EASY-PRIPCI is an observational study evaluating the incidence of abnormal physiology results in patients undergoing repeat angiography after uncomplicated percutaneous intervention (PCI).
Despite successful PCI and complete revascularization, about 25% of patients will present with angina and/or positive exercise testing during follow-up. With recurring or persistent symptoms, a number of those patients will be referred for control angiography. This might create a significant burden for health systems as well as putting patients to undergo further interventions without clear demonstration of ischemia.
Assessing physiology and fractional flow reserve in particular after PCI could represent a further step to determine whether stent implantation and stenosis removal will be effective to relieve subjective and objective signs of ischemia.
Hypothesis:
Resting gradients such as whole cycle Pd/Pa and diastolic dPR and FFR will be abnormal (below ischemic threshold) in > 20% of cases despite optimal stent implantation and angiographic result.
The use of physiology assessment in previously intervened vessels in patients referred for persisting or recurring angina might help operators to decide upon further intervention.
5,598 studies on the registry are indexed under Coronary Artery Disease; 957 are open to participants now.
This study's planned enrollment of 260 is below the median of 336 across 1,947 observational studies indexed under Coronary Artery Disease.
Browse Coronary Artery Disease studies →Laval University is the lead sponsor of 371 studies on the registry; 68 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients returning to the Quebec Heart Institute for a diagnostic angiography and possible PCI within 12 months of a previous uncomplicated PCI with stent implantation.
Exclusion Criteria:
Rate of successful uncomplicated PCI as per coronary physiology ratios
Record the minimal values reported for Pd/Pa, dPR and FFR ratios in the distal vessel after uncomplicated PCI and good angiographic result.Comparison between baseline (pre PCI) and final (post PCI) coronary physiology ratios .
Time frame: Transprocedural, initial and final values
Incidence and types of further interventions or imaging techniques
Record the incidence by type of intervention and diagnostic or imaging techniques
Time frame: Historical and immediately after the procedure, up to 36 months
Residual symptoms and quality of life after repeat angiography
Identify residual symptoms after intervention, and overall immediate quality of life.
Time frame: up to 30 days
Rates of repeat interventions
on previously intervened lesions versus PCI on new lesions
Time frame: Historical and immediately after the procedure
Incidence of successful distal positioning of pressurewire
Time frame: Transprocedural
This study is status unknown, as verified in Jan 2022. You cannot join it, but the record below documents what was studied.
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Laval University