An observational study in Cataract and Glaucoma, sponsored by University of Zurich. Status unknown at 1 site in Switzerland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-03-26.
Sponsored by University of Zurich · Observational
Cystoid macular edema (CME) can limit visual acuity after cataract surgery. Little is known whether the incidence is similar between standard ultrasound phacoemulsification cataract surgery (phaco), femtolaser assisted cataract surgery (FLACS), and combined phacoemulsification cataract surgery plus micro invasive glaucoma surgery (phaco+MIGS) procedures.
Subclinical cystoid macular edema (CME) can limit visual acuity after cataract surgery. Little is known whether the incidence is similar between standard ultrasound phacoemulsification cataract surgery (phaco), femtolaser assisted cataract surgery (FLACS), and combined phacoemulsification cataract surgery plus micro invasive glaucoma surgery (phaco+MIGS) procedures.
The investigators hypothesize that CME incidence will be in the following order: FLACS \< phaco \< phaco+MIGS due to the increase of inflammation with the different surgical procedures.
The study is designed as a single centre, prospective study. The study includes patients with a diagnosis of cataract or cataract and glaucoma who will undergo one of the three above mentioned sürgical procedures at the Department of Ophthalmology at the UniversityHospital Zurich (USZ), Zurich, Switzerland. CME will be assessed by optical coherence tomography of the macular with Heidelberg Spectralis SD-OCT of the Macular at: baseline (i.e. preoperative), 1 week, 1 month, 3 months, and 6 months post-surgery. Furthermore, a swept source Optical Coherence Tomography Angiography (OCT-A) using Zeiss Plex Elite 9000 will be performed at: baseline (i.e. preoperative), 1 week, 1 month, and 6 months post-surgery to image the retinal vessels.
Patient who will undergo cataract surgery or combined catarct MIGS glaucoma surgery at the University Hospital Zurich
Exclusion Criteria:
tandard ultrasound phacoemulsification cataract surgery
Device: SD-OCT · Device: OCT-A
femtolaser assisted cataract surgery
Device: SD-OCT · Device: OCT-A
combined phacoemulsification cataract surgery plus micro invasive glaucoma surgery
Device: SD-OCT · Device: OCT-A
Optical Coherence Tomography of the maculy with Heidelberg Spectralis SD-OCT
swept source Optical Coherence Tomography Angiography with Zeiss Plex Elite 9000 of the macula
incidence of CME
incidence of subclinical cystoid macular edema
Time frame: baseline/preop
incidence of CME
incidence of subclinical cystoid macular edema
Time frame: 1 week postop +/- 4 days
incidence of CME
incidence of subclinical cystoid macular edema
Time frame: 1 month postop +/-2 weeks
incidence of CME
incidence of subclinical cystoid macular edema
Time frame: 3 months postop +/-2 weeks
incidence of CME
incidence of subclinical cystoid macular edema
Time frame: 6 months postop +/-2 weeks
Plan to share: No
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University of Zurich