An observational study in Adrenal Adenoma, Cushing Syndrome and Pheochromocytoma, sponsored by Seoul National University Hospital. Enrolling by invitation at 1 site in Korea, Republic of. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2020-03-18.
Sponsored by Seoul National University Hospital · Observational
The purpose of this study is to investigate the pathologic features, complications, and prognostic factors of functioning adrenal adenoma and suggest follow-up algorithms for adrenal incidentaloma.
The investigators will recruit 150 patients annually for 10 years (adrenal incidentaloma 100 patients, pheochromocytoma 15 patients, primary aldosteronism 25 patients, adrenal cushing syndrome 10 patients, adrenocortical carcinoma 2 patients) and perform hormonal, biochemical, imaging exam according to each disease's clinical guidelines. Based on this, the investigators will identify pathologic features, complications, and prognostic factors of each disease.
study population of this study is the patients who are newly diagnosed with adrenal disease such as adrenal incidentaloma, pheochromocytoma, primary aldosteronism, adrenal cushing syndrome, adrenocortical carcinoma
Exclusion Criteria:
patients who were diagnosed with non-functioning adrenal incidentaloma on computed tomography or magnetic resonance imaging
Other: Hormone study and Imaging study
patients who were diagnosed with pheochromocytoma biochemically or histologically
Other: Hormone study and Imaging study
patients who were diagnosed with primary aldosteronism by saline loading test
Other: Hormone study and Imaging study
patients who were diagnosed with adrenal cushing syndrome by dexamethasone suppression test and 24 urine free cortisol test.
Other: Hormone study and Imaging study
patients who were diagnosed with adrenocortical carcinoma by imaging study or histologic exam
Other: Hormone study and Imaging study
1. Blood (basal hormone and follow up hormone study) 2. Imaging examination including computed tomography scan or magnetic resonance imaging
Number of participants in remission
Remission rate
Time frame: Up to 10 years
Complication of adrenal disease
all complications including deaths
Time frame: Up to 10 years
Plan to share: No
No publications or documents are linked to this record.
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
No contact was published for this record. The registry link below has the sponsor’s details.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Seoul National University Hospital