An interventional study of Static AI-based personalized dietary goal setting and Adaptive AI-based personalized dietary management in Dietary Behavior; Metabolic Health; Obesity; Lifestyle Modification; Metabolic Syndrome Risk, sponsored by Seoul National University Hospital. Recruiting at 1 site in South Korea. Open to participants aged 20 Years to 90 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-15.
Sponsored by Seoul National University Hospital · Not applicable, Interventional, and Prevention
This randomized controlled trial aims to evaluate the effectiveness of an Agentic AI-based personalized dietary management algorithm among adults undergoing health screening. Participants will be assigned to a control group, a static goal AI intervention group, or an adaptive goal AI intervention group and followed for 12 weeks.
This study is a randomized controlled trial designed to evaluate whether an Agentic AI-based personalized dietary management algorithm improves dietary behavior and metabolic health indicators among adults undergoing health screening. Eligible participants will be randomly assigned to one of three groups: standard dietary education and passive dietary recording, AI-generated personalized dietary goals maintained throughout the study period, or adaptive AI-based dietary tracking with dynamic goal adjustment and personalized feedback. Outcomes will be assessed at baseline and after 12 weeks, including dietary evaluation index scores and metabolic health-related clinical indicators.
Exclusion Criteria:
Participants receive standard dietary education and perform passive dietary recording during the 12-week study period.
Participants receive AI-generated personalized dietary goals that are maintained during the 12-week intervention period.
Behavioral: Static AI-based personalized dietary goal setting
Participants receive adaptive AI-based dietary tracking, dynamic goal adjustment, and personalized feedback during the 12-week intervention period.
Behavioral: Adaptive AI-based personalized dietary management
The AI algorithm generates individualized dietary goals based on baseline information. The generated goals are maintained without dynamic adjustment during the intervention period.
The AI algorithm monitors dietary records and relevant participant information, adjusts dietary goals dynamically, and provides personalized feedback to support dietary behavior change.
Change in Dietary Behavior Score
Dietary behavior will be assessed using a 12-item dietary behavior questionnaire derived from a 19-item dietary assessment questionnaire developed and routinely used at Seoul National University Hospital Gangnam Center. Each item is scored on a 3-point scale (1, 3, or 5 points). Total scores range from 12 to 60, with higher scores indicating healthier dietary behaviors. The change in total dietary behavior score from baseline to 12 weeks will be evaluated. unit:score
Time frame: Baseline and 12 weeks
Outcome Measure: Change in Client Satisfaction Questionnaire Score (CSQ-8)
Participant satisfaction with the system will be assessed using the Client Satisfaction Questionnaire-8 (CSQ-8). Total scores range from 8 to 32, with higher scores indicating greater satisfaction with the system.unit:score
Time frame: from baseline to 12 weeks.
Change in System Usability Scale Score (SUS)
System usability will be assessed using the System Usability Scale (SUS). Total scores range from 0 to 100, with higher scores indicating better usability. unit:score
Time frame: from baseline to 12 weeks
Change in Body Mass Index
Change in body mass index from baseline to 12 weeks. Unit: kg/m²
Time frame: Baseline and 12 weeks
Change in Waist Circumference
Change in waist circumference from baseline to 12 weeks. Unit : cm
Time frame: from baseline to 12 weeks
Change in Systolic Blood Pressure
Change in systolic blood pressure from baseline to 12 weeks.Unit:mmHg
Time frame: from baseline to 12 weeks.
Change in Diastolic Blood Pressure
Change in diastolic blood pressure from baseline to 12 weeks. Unit:mmHg
Time frame: from baseline to 12 week
Change in Fasting Glucose
Change in fasting glucose from baseline to 12 weeks. Unit:mg/dL
Time frame: from baseline to 12 weeks.
Change in HbA1c
Change in HbA1c from baseline to 12 weeks.Unit:%
Time frame: from baseline to 12 week
Change in total cholesterol
Changes in total cholesterol from baseline to 12 weeks. unit: mg/dL
Time frame: from baseline to 12 weeks
Change in AST
Changes in AST from baseline to 12 weeks.unit: U/L
Time frame: from baseline to 12 weeks
Change in Body fat mass
Changes in body fat mass from baseline to 12 weeks. unit : kg
Time frame: from baseline to 12 weeks
Change in skeletal muscle mass
Changes in skeletal muscle mass from baseline to 12 weeks. unit:kg
Time frame: from baseline to 12 weeks
Change in percent body fat
Changes in percent body fat from baseline to 12 weeks. unit:%
Time frame: from baseline to 12 weeks.
Change in body weight (kg)
Change in body weight from baseline to 12 weeks unit: kg
Time frame: from baseline to 12 weeks
Changes in LDL cholesterol
Changes in LDL cholesterol from baseline to 12 weeks. unit: mg/dL
Time frame: from baseline to 12 weeks
Changes in HDL cholesterol
Changes in HDL cholesterol from baseline to 12 weeks. unit: mg/dL
Time frame: from baseline to 12 weeks
Changes in triglycerides
Changes in triglycerides from baseline to 12 weeks.
Time frame: from baseline to 12 weeks.
Changes in ALT
Changes in ALT from baseline to 12 weeks.unit: U/L
Time frame: from baseline to 12 weeks
Changes in γ-GTP
Changes in γ-GTP from baseline to 12 weeks.unit: U/L
Time frame: from baseline to 12 weeks
Plan to share: No
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Seoul National University Hospital