An interventional study of Ba Duan Jin and Health Education in Pulmonary Nodules, sponsored by Shanghai University of Traditional Chinese Medicine. Completed at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2025-04-03.
Sponsored by Shanghai University of Traditional Chinese Medicine · Not applicable, Interventional, and Treatment
Among 43 studies in Multiple Pulmonary Nodules with a site in China — 22 open to participants now, 24 under way, none of them phase 3. Multiple Pulmonary Nodules · China.
Among the 43 studies in Multiple Pulmonary Nodules with a site in China, this one is the 15th largest by enrollment of the 21 interventional ones that give a count, is the only one that started in 2017, is one of 18 with no phase, and was the 2nd registered.
99 studies on the registry are indexed under Multiple Pulmonary Nodules; 42 are open to participants now.
This study's enrollment of 60 is below the median of 97 across 46 interventional studies indexed under Multiple Pulmonary Nodules.
Browse Multiple Pulmonary Nodules studies →22 of the 43 studies in Multiple Pulmonary Nodules with a site in China are open now, in 1 country. Each count lists the studies.
Of the 17 Multiple Pulmonary Nodules studies recruiting now, 11 (65%) set no upper age limit and 3 (18%) stop at 75 or younger; 1 take children under 18; 3 take healthy volunteers.
This study: 18 Years to 75 Years · all sexes · no healthy volunteers.
The full table on the hub →43 studies; the count open now beside each. This study's row is marked.
First in 2015; this study’s year is marked. 1 started in 2017.
Median enrollment 138 across the 21 interventional studies, 450 across the 22 observational. Of the 11 that completed or were terminated, 2 (18%) have results posted.
3 of 43 have an industry lead sponsor. The 10 most frequent:
Shanghai University of Traditional Chinese Medicine is the lead sponsor of 102 studies on the registry; 20 are open to participants now.
Shanghai University of Traditional Chinese Medicine has 1 study filed under Multiple Pulmonary Nodules — fewer than ten, so there is no comparison to draw.
10 of the studies in Multiple Pulmonary Nodules with a site in China that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06518655ChromX HealthDifferentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath | 2026-12-30 |
| NCT07595120Shanghai Pulmonary Hospital, Shanghai, ChinaApplication of Electromagnetic Navigation System in Pulmonary Nodule Localization | 2027-01 |
| NCT07719959Peking Union Medical College HospitalA Randomized Controlled Trial of 3D Airway Reconstruction for Precise Double-Lumen Bronchial Intubation | 2027-03 |
| NCT07849400Diansan SuVideo-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery | 2027-03-30 |
| NCT07277088Jiayuan SunThe Percutaneous Interventional Surgery Control System for Pulmonary Nodule Biopsy | 2027-05-30 |
Among the 43 studies in Multiple Pulmonary Nodules with a site in China, from their registry updates:
Many researches shows that Ba Duan Jin has clinical efficacy on cancer rehabilitation, respiratory diseases, psychological health, quality of life and so on. Studies examining the effects of Ba Duan Jin on patients with pulmonary nodules are sparse. Therefore, the aims of the present study are: 1) to examine the effects of Ba Duan Jin on physical and psychological condition, and 2) to examine the effects of Ba Duan Jin on quality of life.
In recent years, with advancement in computed tomography (CT) technology and its widespread use, pulmonary nodules are common incidental findings. Pulmonary nodules are used to appear as well-circumscribed radiographic opacity. They can be single or multiple. There are multiple causes of pulmonary nodules. Most nodules are benign, but some may also represent bronchogenic carcinoma or metastatic lesions. The prevalence of malignancy is detected nodules varies between 0.2% and 18%. Thus, the preoperative individuals would suffer from depression or anxiety caused by uncertain progression of pulmonary nodules; the postoperative individuals would suffer from both physical and mental trauma.
There is growing interest in non-pharmacological approaches that could potentially improve pulmonary nodules patients' physical condition, psychological condition and quality of life.
Ba Duan Jin, a traditional Chinese health-preserving technique, combines the traditional Chinese medicine and traditional Chinese philosophy and embrace the body, breath and spirit. There is substantial evidence that Ba Duan Jin has benefits for cancer rehabilitation, respiratory diseases, psychological health, and quality of life. The effects of Ba Duan Jin on patients with pulmonary nodules are yet to be further investigated.
The present pilot clinical study aims to apply Ba Duan Jin to patients with pulmonary nodules, and to evaluate the effects on physical (pulmonary function), psychological (depression and anxiety), and quality of life. Participants allocated to the Health Education Group take part in the 16-week health education including work, rest, diet and other basic programs according to the different conditions of participants. Participants allocated to the Ba Duan Jin Group take part in the 16-week Ba Duan Jin plus health education program. The study plans to enroll 60 participants in 2 years (30 for Ba Duan Jin plus health education program, and 30 for health education program), expecting that Ba Duan Jin has a better effect on improving physical condition, psychological condition and quality of life.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Ba Duan Jin plus health education. Participants take part in 16-week program. The health education is conducted as the Health Education Group. Besides, the participants attended two 90-minute sessions of group-based Ba Duan Jin training per week and practiced at least three 30-minute Ba Duan Jin sessions at home per day.
Behavioral: Ba Duan Jin · Behavioral: Health Education
Health education. Participants take part in 16-week program. The health education includes work, rest, diet and other basic programs according to the different conditions of participants.
Behavioral: Health Education
Ba Duan Jin, a traditional Chinese health-preserving technique, combines the traditional Chinese medicine and traditional Chinese philosophy and embrace the body, breath and spirit. Ba Duan Jin consists of eight main movements. According to traditional theory, every movement has unique effect to different Zang-fu organs.
Also known as: Eight-section Brocade
Health education includes work, rest, diet and other basic programs according to the different conditions of participants.
Vital Capacity in liters (VC)
VC, a measure of pulmonary function, is the maximum amount of air a person can expel from the lungs after a maximum inhalation.
Time frame: 16 weeks
Forced Vital Capacity in liters (FVC)
FVC, a measure of pulmonary function, is the volume of air that can forcibly be blown out after full inspiration.
Time frame: 16 weeks
Forced Expiratory Volume in one second in liters (FEV1)
FEV1, a measure of pulmonary function, is the volume of air that can forcibly be blown out in one second, after full inspiration.
Time frame: 16 weeks
FEV1/FVC in percents (FEV1%)
FEV1% is the ratio of FEV1 to FVC.
Time frame: 16 weeks
Peak Expiratory Flow in liters (PEF)
PEF, a measure of pulmonary function, is the maximal flow (or speed) achieved during the maximally forced expiration initiated at full inspiration.
Time frame: 16 weeks
the Zung Self-Rating Anxiety Scale (SAS)
The SAS, designed by Duke University psychiatrist William W.K. Zung MD, is a 20-item self-report assessment built to measure anxiety level. Each items points accumulated as raw score, then the raw score will be converted into a percentage (the SAS index); the higher the SAS index, the greater the severity of anxious symptoms.
Time frame: 16 weeks
the Zung Self-Rating Depression Scale (SDS)
The SDS, designed by Duke University psychiatrist William W.K. Zung MD, is a 20-item self-report assessment built to measure depression level. Each items points accumulated as raw score, then the raw score will be converted into a percentage (the SDS index); the higher the SDS index, the greater the severity of depressive symptoms.
Time frame: 16 weeks
the MOS 36-Item Short Form Health Survey(SF-36)
The SF-36 is a 36-item, patient-report survey of patient health status. It consists of eight scaled scores and each scale is directly transformed into a 0-100 scale on the assumption that each question carries equal weight. Higher scores indicate a better health-related quality of life.
Time frame: 16 weeks
CT scan of the Lung(s)
Follow-up CT scan imaging is required to observe the changes of pulmonary nodules in size, density, type and so on.
Time frame: 16 weeks
Plan to share: No
Ran from Feb 2017 to primary completion in Dec 2019, 34 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Mar 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Shanghai University of Traditional Chinese Medicine →