CompletedNCT02854813Updated May 31, 2017

Overactive Bladder in Elderly Patients- An Early Warning of Coronary Artery Disease

An observational study in Overactive Bladder Syndrome and Coronary Artery Disease, sponsored by Ankara Training and Research Hospital. Completed at 1 site in Turkey. Open to participants aged 65 Years to 90 Years. Per ClinicalTrials.gov, last updated 2017-05-31.

Sponsored by Ankara Training and Research Hospital · Observational

Study type: Observational
Model: Cohort
Time perspective: Prospective
Enrollment: 250
Ages: 65 Years to 90 Years
Sex: All

Study summary

Investigators aimed to investigate the association between over active bladder and coronary artery disease as demonstrated on coronary angiography.

Read the detailed description

The close relationship has been demonstrated between pelvic ischemia and overactive bladder (OAB) in a study involving elderly patients. In this study, it has been found that pelvic ischemia has triggered OAB and it has been related with cardiac ischemia. The aim of this study was to delineate the correlation between OAB and the degree of coronary artery stenosis as demonstrated on coronary angiography.

Conditions studied

Overactive Bladder Syndrome
Coronary Artery Disease

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Keywords

overactive bladder
coronary artery disease
gensini score

In context

Urinary Bladder, Overactive

855 studies on the registry are indexed under Urinary Bladder, Overactive; 125 are open to participants now.

This study's enrollment of 250 is above the median of 109 across 166 observational studies indexed under Urinary Bladder, Overactive.

Browse Urinary Bladder, Overactive studies →

Lead sponsor

Ankara Training and Research Hospital is the lead sponsor of 47 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 65 Years to 90 Years
Sexes eligible: All
Accepts healthy volunteers: No
Sampling method: Non-probability sample

Study population

patients, whom were diagnosed to undergo coronary angiography in a center of cardiology between January 2016 and January 2017 were evaluated prospectively.

Inclusion criteria

patients, whom were diagnosed to undergo coronary angiography in a center of cardiology

Exclusion criteria

Exclusion Criteria:

a maximum flow rate of 15 ml. per second or less,
residual volume of 100 cc or more,
diabetes mellitus,
neurologic disease,
prostate or bladder cancer,
renal failure,
urinary tract infection,
nephrolithiasis or pelvic surgery,
patients with a history of percutaneous coronary intervention or coronary artery bypass grafting

Study design

Observational model: Cohort
Time perspective: Prospective
Enrollment: 250 participants (actual)
Target follow-up: 3 Months
Patient registry: Yes

Groups and cohorts

Group 1
Patients with a OAB-V8 score ≥8
Group 2
Patients with a OAB-V8 score \<8

What researchers measure

Primary outcomes

Over active bladder V8 questionnaire score
Time frame: 1 week

Study locations

1 site

Ankara Training and Research Hospital
Ankara, 06340, Turkey

References and documents

Publications

Tarcan T, Azadzoi KM, Siroky MB, Goldstein I, Krane RJ. Age-related erectile and voiding dysfunction: the role of arterial insufficiency. Br J Urol. 1998 Dec;82 Suppl 1:26-33. doi: 10.1046/j.1464-410x.1998.0820s1026.x. No abstract available. PubMed 9883259 ↗
De EJ, Hou P, Estrera AL, Sdringola S, Kramer LA, Graves DE, Westney OL. Pelvic ischemia is measurable and symptomatic in patients with coronary artery disease: a novel application of dynamic contrast-enhanced magnetic resonance imaging. J Sex Med. 2008 Nov;5(11):2635-45. doi: 10.1111/j.1743-6109.2008.00969.x. Epub 2008 Aug 26. PubMed 18761598 ↗

Individual participant data

Plan to share: Yes

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on May 31, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT02854813
Lead sponsor: Ankara Training and Research Hospital
Responsible party: Muhammet Fatih Kilinc (M.D., Ankara Training and Research Hospital) — Principal investigator
First posted: Aug 3, 2016
Start date: Jan 2016
Primary completion: Jan 2017
Completion: Jan 2017
Last update: May 31, 2017

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2017. You cannot join it, but the record below documents what was studied.

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Discussion

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