ClinicalTrials.gg
Enrolling by invitationNCT07143084Updated Mar 19, 2026

Investigation of the Relationship Between Nutritional Status Assessment and Frailty in Critical Care Patients

An observational study in Fraility and Critical Illness, sponsored by Ankara Training and Research Hospital. Enrolling by invitation at 1 site in Turkey (Türkiye). Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2026-03-19.

Sponsored by Ankara Training and Research Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
100
Ages
65 Years and older
Sex
All
01

Study summary

This study aims to understand the effects of these two parameters on clinical outcomes by examining the relationship between NUTRIC and CONUT scores in intensive care patients. The results of the study may contribute to the development of new approaches to the treatment process of patients by better understanding the relationship between nutritional status and pre-hospital frailty in intensive care units. In addition, eliminating the deficiencies in this area will pave the way for the creation of more effective and personalized treatment plans for similar patients.

02

Conditions studied

  • Fraility
  • Critical Illness

Browse trials for

Keywords

  • CONUT
  • Fraility
  • NUTRIC Score
03

In context

Critical Illness

1,780 studies on the registry are indexed under Critical Illness; 442 are open to participants now.

This study's planned enrollment of 100 is below the median of 140 across 814 observational studies indexed under Critical Illness.

Browse Critical Illness studies →

Lead sponsor

Ankara Training and Research Hospital is the lead sponsor of 48 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Over 65 years, critically ill patients, who are submitted to ICU.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • over 65
  • 48 hours min. ICU stay

Exclusion criteria

Exclusion Criteria:

  • Patients who are under 65 years of age
  • whose intensive care stay does not exceed 48 hours
  • who have missing data for serum albumin or lymphocyte count or total cholesterol,
  • who have been diagnosed with hematological diseases such as leukemia or lymphoma
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
100 participants (estimated)
Target follow-up
2 Days
Patient registry
Yes

Groups and cohorts

  • ICU Patients above 65 years old
06

What researchers measure

Primary outcomes

  1. Correlation between CONUT scale and frailty in intensive care patients

    To evaluate the correlation between the CONUT scale and frailty, Pearson or Spearman correlation analysis will be performed depending on suitability for normal distribution. Logistic regression analysis will be performed to assess the independent association between CONUT scale and frailty. Potential confounding variables such as age, gender, APACHE II score, and activities of daily living will be included in the regression model.

    Time frame: From enrollment 2 days

Secondary outcomes

  1. Association of NUTRIC score and CONUT scale with clinical outcomes

    To evaluate the correlation between the NUTRIC score and CONUT scale with clinical outcome, Pearson or Spearman correlation analysis will be performed depending on suitability for normal distribution. Logistic regression analysis will be performed to assess the independent association between CONUT scale and NUTRIC score. Potential confounding variables such as age, gender, APACHE II score, and activities of daily living will be included in the regression model.

    Time frame: From enrollment to through study completion an average of 1 year

07

Study locations

1 site
08

References and documents

Publications

  • Auza-Santivañez, J. C., Perez, J. S., Lara, Y. D., León, D. O., Condori-Villca, N., & Loaces, J. P. A. Predictive value of the CONUT scale in the early detection of nutritional risk and its relationship with mortality in critically ill patients.
  • Kos, M., Titiz, H., Onec, B., Soysal, T., Kutlucan, A., Emen, S. S., & Kutlucan, L. (2016). Association of "controlling nutritional status index" and "prognostic nutritional index" with intensive care unit survival in elderly patients. European Geriatric Medicine, 7(1), 13-17.
  • Lo Buglio A, Bellanti F, Capurso C, Vendemiale G. Controlling Nutritional Status (CONUT) Score as a Predictive Marker in Hospitalized Frail Elderly Patients. J Pers Med. 2023 Jul 10;13(7):1119. doi: 10.3390/jpm13071119. PubMed 37511732 ↗

Individual participant data

Plan to share: Yes

Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 19, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07143084
Lead sponsor
Ankara Training and Research Hospital
Responsible party
Ayşe EKEN (Principal Investigator, Ankara Training and Research Hospital) — Principal investigator
First posted
Aug 27, 2025
Start date
May 15, 2025
Primary completion
Dec 15, 2026 (estimated)
Completion
May 1, 2027 (estimated)
Last update
Mar 19, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

No contact was published for this record. The registry link below has the sponsor’s details.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion