An interventional study of Suspension in a harness and Climbing in Circulatory Collapse, Circulatory Failure and Syncope, Vasovagal, Neurally-Mediated, sponsored by Institute of Mountain Emergency Medicine. Completed. Open to male participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-04-06.
Sponsored by Institute of Mountain Emergency Medicine · Not applicable, Interventional, and Basic science
Suspension syndrome refers to a potentially life-threatening condition that can occur in unconscious persons after prolonged suspension in a harness. To date, our understanding of the pathophysiology and appropriate treatment is based primarily on case reports and expert opinion. The main pathophysiological hypothesis implicates blood pooling in the lower extremity and lack of return via muscle pumping. However, a recent French study could not support this hypothesis. Other mechanisms, such as a central vagal reflex may play a role in the pathophysiology of suspension syndrome. The aim of this study is to better understand the pathophysiological basis of suspension syndrome and to develop practical recommendations for prevention and treatment.
226 studies on the registry are indexed under Syncope; 45 are open to participants now.
This study's enrollment of 20 is below the median of 79 across 126 interventional studies indexed under Syncope.
Browse Syncope studies →Institute of Mountain Emergency Medicine is the lead sponsor of 20 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Free Suspension in a harness after baseline measurements and without prior climbing
Other: Suspension in a harness
Free Suspension in a harness after baseline measurements and after climbing in moderate intensity for 10 minutes
Other: Suspension in a harness · Other: Climbing
Heart rate
Time frame: Change from baseline (measurement at minute 0) -> suspension phase (minute 10, timepoint immediately before interruption of suspension phase [max 60 minutes]) -> minute 5 and minute 15 after suspension phase
Blood pressure
Time frame: Change from baseline (measurement at minute 0) -> suspension phase (minute 10, timepoint immediately before interruption of suspension phase [max 60 minutes]) -> minute 5 and minute 15 after suspension phase
Change in maximal Diameter of superficial femoral vein
Ultrasound measurement of the Diameter of the superficial femoral vein in millimeters
Time frame: Change from baseline (measurement at minute 0) -> suspension phase (minute 10, timepoint immediately before interruption of suspension phase [max 60 minutes]) -> minute 5 and minute 15 after suspension phase
Change in interbeat-interval
electrocardiographic measurement of interbeat interval in milliseconds (ms)
Time frame: Change from baseline (measurement at minute 0) -> suspension phase (minute 10, timepoint immediately before interruption of suspension phase [max 60 minutes]) -> minute 5 and minute 15 after suspension phase
No study locations are listed for this record.
Plan to share: No
This study is completed, as verified in Apr 2016. You cannot join it, but the record below documents what was studied.
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Institute of Mountain Emergency Medicine