An observational study in Hyperglycemia, Hypercholesterolemia and Persistent Postoperative Pain, sponsored by Coxa, Hospital for Joint Replacement. Terminated at 1 site in Finland. Open to participants aged 18 Years to 120 Years. Per ClinicalTrials.gov, last updated 2023-10-18.
Sponsored by Coxa, Hospital for Joint Replacement · Observational
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Among 11 studies in Hyperglycemia with a site in Finland — 1 open to participants now, 2 under way, none of them phase 3. Hyperglycemia · Finland.
Among the 11 studies in Hyperglycemia with a site in Finland, this one is one of 2 that started in 2012, is one of 3 observational ones, and was the 4th registered.
801 studies on the registry are indexed under Hyperglycemia; 115 are open to participants now.
Browse Hyperglycemia studies →1 of the 11 studies in Hyperglycemia with a site in Finland is open now. Recruiting first, the newest first:
University of Eastern Finland · Sites in Finland
Ages 30–65
A study can be open while its sites in Finland have not opened yet or have stopped. Only those recruiting at a site in Finland →
Of the 71 Hyperglycemia studies recruiting now, 42 (59%) set no upper age limit and 23 (32%) stop at 75 or younger; 10 take children under 18; 15 take healthy volunteers.
This study: 18 Years to 120 Years · all sexes · no healthy volunteers.
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11 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 2 started in 2012.
This study's enrollment of 155 is above the median of 120 across 154 observational studies indexed under Hyperglycemia.
Median enrollment 26 across the 8 interventional studies, 155 across the 3 observational. Of the 9 that completed or were terminated, 1 (11%) have results posted.
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2 of 11 have an industry lead sponsor. The 6 most frequent:
Coxa, Hospital for Joint Replacement is the lead sponsor of 8 studies on the registry; 1 is open to participants now.
Coxa, Hospital for Joint Replacement has 2 studies filed under Hyperglycemia — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 11 studies in Hyperglycemia with a site in Finland, from their registry updates:
Nothing recorded among them since 2026-09-25.
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Osteoarthritis patients undergoing primary hip and knee replacement are followed-up and changes in their glucose metabolism and other metabolic parameters (obesity, cholesterol levels) are examined. Persistent postoperative pain is examined as secondary outcome.
Glucose metabolism disorders (diabetes and pre-diabetes) and metabolic syndrome are common in joint replacement recipients. Improved physical activity following joint replacement could lead to better glucose control in diabetes and ameliorate impaired glucose and cholesterol levels. In this study patients previously recruited to "Perioperative Hyperglycaemia in Primary Total Hip and Knee Replacement" study are being followed-up for one year in order to analyze if joint replacements have an effect on these metabolic abnormalities. In addition, the effect of glucose metabolism disorders on occurrence of persistent pain after surgery is analyzed.
tertiary care clinic
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Exclusion Criteria:
Hip and knee replacement recipients (with osteoarthritis) enrolled previously into "Perioperative Hyperglycaemia in Primary Total Hip and Knee Replacement" study (NCT01021826).
Change in glucose tolerance, measured using oral glucose tolerance test
The patients are grouped into three groups that are evaluated 12, 18 and ca. 24 months after surgery.
Time frame: Baseline and 12-24 months after surgery
Change in cholesterol levels (HDL, LDL, triglycerides)
Time frame: Baseline and 12-24 months after surgery
Prolonged postoperative pain
Assessed using visual analog scale. Patients are divided in three groups that are evaluated 12, 18 and 24 months after surgery.
Time frame: 12-24 months after surgery
Change in plasma adipokine and cytokine concentrations
Time frame: Baseline and 12-24 months after surgery.
The record gives a start of Apr 2012, a primary completion of Aug 2012 and a completion of Jun 2017. It does not say whether these dates are actual or estimated.
How these figures are worked out, and which studies are left out of them.
This study is terminated, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.
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Coxa, Hospital for Joint Replacement