An interventional study of NexGen and Persona in Osteoarthritis, Knee, Arthroplasty and Total Knee Replacement, sponsored by Coxa, Hospital for Joint Replacement. Status unknown at 1 site in Finland. Open to participants aged 50 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-02-04.
Sponsored by Coxa, Hospital for Joint Replacement · Not applicable, Interventional, and Treatment
Help build ClinicalTrials.gg — short surveys, remote interviews or testing, in your language. Take part →
Among 16 studies in Osteoarthritis, Knee with a site in Finland — none open to participants now, 1 under way, none of them phase 3. Osteoarthritis, Knee · Finland.
Among the 16 studies in Osteoarthritis, Knee with a site in Finland, this one is the 4th largest by enrollment of the 15 interventional ones that give a count, is one of 2 that started in 2015, is one of 10 with no phase, and was the 12th registered.
3,294 studies on the registry are indexed under Osteoarthritis, Knee; 623 are open to participants now.
Browse Osteoarthritis, Knee studies →None of the 16 studies in Osteoarthritis, Knee with a site in Finland is open now. The open studies under Osteoarthritis, Knee, anywhere →
Of the 383 Osteoarthritis, Knee studies recruiting now, 177 (46%) set no upper age limit and 113 (30%) stop at 75 or younger; 19 take children under 18; 39 take healthy volunteers.
This study: 50 Years to 70 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
16 studies; the count open now beside each. This study's row is marked.
First in 2002; this study’s year is marked. 2 started in 2015.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 240 is above the median of 68 across 2,716 interventional studies indexed under Osteoarthritis, Knee.
Median enrollment 140 across the 15 interventional studies, 12 across the 1 observational. Of the 12 that completed or were terminated, 2 (17%) have results posted.
This tab as a report to print or save as PDF → With an account.
3 of 16 have an industry lead sponsor. The 10 most frequent:
Coxa, Hospital for Joint Replacement is the lead sponsor of 8 studies on the registry; 1 is open to participants now.
Coxa, Hospital for Joint Replacement has 2 studies filed under Osteoarthritis, Knee — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 16 studies in Osteoarthritis, Knee with a site in Finland, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
The present randomized controlled trial is designed to compare one novel total knee replacement (TKR) design and two conventional TKR designs in terms of functional outcome. 80 patients will be randomized in each of the three arms (240 altogether).
The study will compare the short-term functional outcome (at 2 years) of TKR performed with a novel TKR design (Persona , Zimmer, Warsaw, IN, USA) against TKRs performed with two conventional designs (PFC, DePuy, Warsaw, IN, USA and Nexgen, Zimmer, Warsaw, IN, USA).
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
PFC, Conventional design Perioperative treatment will be carried out according to routine protocol of the hospital.
Device: NexGen · Device: Persona
NexGen, Conventional design Perioperative treatment will be carried out according to routine protocol of the hospital.
Device: Persona · Device: PFC
Persona, Novel design Perioperative treatment will be carried out according to routine protocol of the hospital.
Device: NexGen · Device: PFC
Comparing two conventional designs and one novel design
Comparing two conventional designs and one novel design
Comparing two conventional designs and one novel design
Changes in patient reported outcome measures scores (PROMs), Functional improvement
Oxford Knee Score (OKS)
Time frame: preoperative, postoperative at 2-3 months, at 1 year and at 2 years
Changes in PROMs, Functional improvement
Forgotten Joint Score (FJS)
Time frame: preoperative, postoperative at 2-3 months, at 1 year and at 2 years
Changes in health-related quality of life (HRQoL)
15D
Time frame: preoperative, postoperative at 2-3 months, at 1 year and at 2 years
Changes in activity rating scale
UCLA activity score
Time frame: preoperative, postoperative at 2-3 months, at 1 year and at 2 years
Changes in pain scale measurement
VAS pain scale
Time frame: preoperative, postoperative at 2-3 months, at 1 year and at 2 years
Plan to share: No
Started Sep 2015 (actual). Primary completion is estimated for May 2021, 68 months after the start.
Of 1,111 non-industry interventional studies with no phase under Osteoarthritis, Knee, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 36. This study's planned 68 months is above that.
Counting every sponsor, half of 1,251 studies reached it within 18 months; a quarter within 8 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Coxa, Hospital for Joint Replacement