CClinicalTrials.gg
Status unknownNCT01105923MAPLEUpdated Feb 2, 2015

Study of an Intervention to Improve Problem List Accuracy and Use

An interventional study of MAPLE in Attention Deficit Disorder With Hyperactivity, Asthma and COPD, sponsored by Brigham and Women's Hospital. Status unknown at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-02-02.

Sponsored by Brigham and Women's Hospital · Not applicable, Interventional, and Diagnostic

The sponsor has not verified this record recently (last verified Jan 2015), so the status shown — last known as Active, not recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
140
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians the opportunity to correct them. The investigators will randomize the clinics that will receive the intervention and formally evaluate the study after a period of 6 months for improved problem list completeness to determine the effectiveness of our intervention.

Read the detailed description

The clinical problem list is a cornerstone of the problem-oriented medical record. Problem lists are used in a variety of ways throughout the process of clinical care. In addition to its use by clinicians, the problem list is also critical for decision support and quality measurement.

Patients with gaps in their problem list face significant risks. For example, if a hypothetical patient has diabetes properly documented, his clinician would receive appropriate alerts and reminders to guide care. Additionally, the patient might be included in special care management programs and the quality of care provided to him would be measured and tracked. Without diabetes on his problem list, he might receive none of these benefits.

In this study, the investigators developed an clinical decision support intervention that will identify patients with problem lists gaps. The investigators will alert providers of these likely gaps and offer providers the opportunity to correct them.

02

Conditions studied

  • Attention Deficit Disorder With Hyperactivity
  • Asthma
  • COPD
  • Breast Cancer
  • Coronary Artery Disease
  • Congestive Heart Failure
  • Diabetes
  • Glaucoma
  • Hemophilia
  • Hypertension
  • Hyperthyroidism
  • Hypothyroidism
  • Myasthenia Gravis
  • Osteoporosis
  • Osteopenia
  • Renal Failure
  • Renal Insufficiency
  • Sickle Cell Disease
  • Stroke
03

In context

Myasthenia Gravis

324 studies on the registry are indexed under Myasthenia Gravis; 146 are open to participants now.

This study's planned enrollment of 140 is above the median of 44 across 212 interventional studies indexed under Myasthenia Gravis.

Browse Myasthenia Gravis studies →

Lead sponsor

Brigham and Women's Hospital is the lead sponsor of 1,236 studies on the registry; 224 are open to participants now.

Of its 116 completed or terminated interventional studies of FDA-regulated products, 64 (55%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Independent healthcare provider (physician, NP, PA)
  • Practices at participating site

Exclusion criteria

Exclusion Criteria:

  • None
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
140 participants (estimated)

Study arms

  • Experimental
    Receive CDS intervention

    Providers in clinics that will receive the CDS alert, as their clinic was randomized into our study.

    Other: MAPLE

  • No intervention
    No CDS intervention

Interventions

  • OtherMAPLE

    MAPLE is a CDS intervention within the EHR that will alert providers to problem lists gaps and present an opportunity to correct them.

06

What researchers measure

Primary outcomes

  1. Intervention acceptance

    Of those providers who were shown (or who would have been shown, for the control group) the intervention, the number that added a problem across control and intervention groups.

    Time frame: 6 months (May 2010-Nov2010)

Secondary outcomes

  1. Problem list prevalence

    Number of patients with selected problems on their problem list pre and post intervention across intervention and control groups.

    Time frame: pre and post intervention

  2. Problem list incidence

    For the conditions of interest, the percent of patients that had the problem added during the study period

    Time frame: pre and post intervention

  3. Quality improvement based on problem list accuracy/completion

    For those with problems added due to the intervention, the number of new triggered reminders or other clinical actions.

    Time frame: post intervention

07

Study locations

1 site
  • Brigham and Women's Hospital
    Boston, Massachusetts 02115, United States
08

References and documents

Publications

  • Wright A, Pang J, Feblowitz JC, Maloney FL, Wilcox AR, McLoughlin KS, Ramelson H, Schneider L, Bates DW. Improving completeness of electronic problem lists through clinical decision support: a randomized, controlled trial. J Am Med Inform Assoc. 2012 Jul-Aug;19(4):555-61. doi: 10.1136/amiajnl-2011-000521. Epub 2012 Jan 3. PubMed 22215056 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 2, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01105923
Lead sponsor
Brigham and Women's Hospital
Responsible party
Adam Wright (Senior Scientist, Brigham and Women's Hospital) — Principal investigator
First posted
Apr 19, 2010
Start date
May 2010
Primary completion
Nov 2010
Completion
Nov 2017 (estimated)
Last update
Feb 2, 2015

Study contacts

Adam Wright, PhD
principal investigator · Brigham and Women's Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2015. You cannot join it, but the record below documents what was studied.

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