A Phase 2/3 interventional study of Cognitive-behavioral group and Cognitive-behavioral bibliotherapy in Depression, sponsored by Oregon Research Institute. Completed at 1 site in United States. Open to participants aged 13 Years to 19 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-03-12.
Sponsored by Oregon Research Institute · Phase 2/3, Interventional, and Prevention
This study will test the effectiveness of two programs for preventing depression in adolescents.
Major depression is one of the most common psychiatric disorders experienced by adolescents. Even adolescents with depressive symptoms below the level of diagnosis are at increased risk of a range of future problems, such as psychiatric disorders, impaired social functioning, and substance abuse.
Depression prevention therapies have had mixed results. Those that are implemented universally have shown little efficacy, although those that specifically target adolescents at risk of depression have shown greater efficacy. A large scale effectiveness trial-one that applies treatments outside of a lab in "real world" settings-of a targeted depression prevention therapy has not been conducted. This study will test the effectiveness of two therapies for preventing depression in adolescents. The first is a brief, group cognitive-behavioral depression prevention program, and the second is bibliotherapy, which involves giving participants a self-help book for depression. Bibliotherapy has shown efficacy in previous research but has not been examined in an effectiveness trial.
Participation in this study will last 24 months. Participants will be randomly assigned to one of three conditions: a six-session, cognitive-behavioral depression prevention group; a bibliotherapy group; and an assessment only group. Participants in the cognitive-behavioral group will meet with a study therapist and other group members to learn strategies for preventing depression. Participants in the bibliotherapy group will be given a self-help book titled "Feeling Good" with information on preventing depression. Participants in the assessment only group will receive a pamphlet on depression symptoms and treatment. All participants will complete assessments at baseline; after the cognitive-behavioral group has been completed; and at 6-, 12-, 18-, and 24-month follow-ups. These assessments will include an interview about depression symptoms and a survey about thoughts, feelings, actions, depression, and substance abuse.
8,057 studies on the registry are indexed under Depression; 1,641 are open to participants now.
This study's enrollment of 390 is above the median of 84 across 6,720 interventional studies indexed under Depression.
Browse Depression studies →Oregon Research Institute is the lead sponsor of 70 studies on the registry; 5 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Participants will receive a cognitive-behavioral group intervention.
Behavioral: Cognitive-behavioral group
Participants will receive cognitive-behavioral bibliotherapy.
Behavioral: Cognitive-behavioral bibliotherapy
Participants will only complete study assessments.
Six sessions of cognitive-behavioral depression prevention group intervention
Cognitive-behavioral bibliotherapy, delivered from the book "Feeling Good"
Depressive symptoms obtained from Kiddie-Schedule for Affective Disorders and Schizophrenia (K-SADS)
Time frame: Measured at baseline; post-treatment; and after 6, 12, 18, and 24 months
Score on Beck Depression Inventory (BDI)
Time frame: Measured at baseline; post-treatment; and after 6, 12, 18, and 24 months
This study is completed, as verified in Mar 2014. You cannot join it, but the record below documents what was studied.
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Oregon Research Institute