An observational study in Tricuspid Atresia, Hypoplastic Left Heart Syndrome and Unbalanced AV Canal, sponsored by University of California, San Francisco. Completed at 1 site in United States. Open to participants aged 1 Month to 6 Years. Per ClinicalTrials.gov, last updated 2015-05-14.
Sponsored by University of California, San Francisco · Observational
The purpose of this study is to determine if children with heart disease where there is only one pumping chamber("ventricle") have proteins (biomarkers") in the blood that can be used to monitor the function of their heart.
We will investigate whether levels of blood proteins in children with well-functioning hearts with one ("single") ventricle are similar to levels of these blood proteins in children with two ventricles. For children with hearts with a single ventricle, we will examine blood proteins at various levels of heart function. To assess blood protein levels, we will collect small (6 mL) samples of blood. Heart function will be determined by existing clinical scoring systems. Enrolled patients will receive an echocardiogram, which is a dynamic ultrasound picture of the beating heart.
65 studies on the registry are indexed under Hypoplastic Left Heart Syndrome; 12 are open to participants now.
This study's enrollment of 71 is close to the median of 71 across 23 observational studies indexed under Hypoplastic Left Heart Syndrome.
Browse Hypoplastic Left Heart Syndrome studies →University of California, San Francisco is the lead sponsor of 2,164 studies on the registry; 368 are open to participants now.
Of its 267 completed or terminated interventional studies of FDA-regulated products, 199 (75%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients presenting to the UCSF Pediatric Heart Center.
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Exclusion Criteria:
Group one consists of children 1 month - 6 years old who have structurally normal hearts, no heart failure, and a patent ductus arteriosus (PDA).
Group two consists of children 1 month - 6 years old who have single ventricle physiology. Children with and without heart failure may participate.
Heart failure, as assessed by clinical scoring systems.
Time frame: Cross-sectional. We will obtain blood samples and assess for heart failure (function) concurrently when patients present to the Pediatric Heart Center
Echocardiographic indices.
Time frame: Cross-sectional
This study is completed, as verified in May 2015. You cannot join it, but the record below documents what was studied.
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Hypoplastic Left Heart Syndrome →
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