A Phase 2 interventional study of Psychodynamic Therapy and Optimized Community Care in Borderline Personality Disorder and Alcohol Use Disorder, sponsored by State University of New York - Upstate Medical University. Completed at 1 site in United States. Open to participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-01-06.
Sponsored by State University of New York - Upstate Medical University · Phase 2, Interventional, and Treatment
The purpose of the study is to determine the feasibility and effectiveness of a modified form of psychodynamic psychotherapy for persons suffering from co-occurring borderline personality disorder and an alcohol use disorder.
Borderline Personality Disorder (BPD) is a condition that can cause significant distress and increased risk of death. Many persons with BPD also have an alcohol use disorder (AUD) and there is evidence that this can worsen the outcome and course of both disorders.
A manual-based form of psychodynamic therapy (PT), labeled dynamic deconstructive psychotherapy, has been developed for particularly challenging patients with BPD, especially those with co-occurring substance use disorders. It aims to remediate specific neurocognitive capacities that are responsible for processing of emotional experiences, and so diminishes symptoms of BPD and promotes the development of a coherent and differentiated self-structure. PT has been shown to be helpful for BPD, but has not been tested for people who have BPD with co-occurring substance use disorders.
The proposed study is a randomized controlled trial of PT for persons with BPD and co-occurring AUD that will generate some initial data that can be used to determine the need and feasibility for further outcome studies. Participants are randomized to either a study group receiving weekly PT or to a control group receiving usual care. Enrollment is 15 participants in each group. The study group will receive 12-18 months of PT, with naturalistic follow-up. Outcome measures are administered by a research assistant at enrollment, 3 months, 6 months, 9 months, 12 months, and 30 months.
The investigators anticipate that the PT group will show trends towards better retention in treatment and greater reduction in parasuicides, alcohol misuse, and institutional care. If so, this would have important and positive implications for the large group of patients who suffer from BPD and co-occurring AUD.
1,606 studies on the registry are indexed under Alcoholism; 329 are open to participants now.
This study's enrollment of 30 is below the median of 87 across 1,371 interventional studies indexed under Alcoholism.
Browse Alcoholism studies →State University of New York - Upstate Medical University is the lead sponsor of 154 studies on the registry; 17 are open to participants now.
Of its 11 completed or terminated interventional studies of FDA-regulated products, 4 (36%) have results posted.
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Exclusion Criteria:
weekly individual psychotherapy of 50 minute duration lasting 12-18 months
Behavioral: Psychodynamic Therapy
eclectic weekly individual and group psychotherapy, as well as drug and alcohol rehabilitation
Behavioral: Optimized Community Care
Dynamic deconstructive psychotherapy is a time-limited (12-18 month) manual-based form of psychodynamic therapy that aims to remediate specific neurocognitive capacities responsible for processing of emotional experiences.
Also known as: Dynamic Deconstructive Psychotherapy
individual and group psychotherapy in a private practice, clinic, and/or rehab setting, with an eclectic orientation
Also known as: Treatment as Usual
episodes of parasuicide, alcohol intoxication, institutional care
Time frame: 12 months
depression, dissociation, core symptoms of borderline pd, perceived social support
Time frame: 12 months
This study is completed, as verified in Jan 2015. You cannot join it, but the record below documents what was studied.
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State University of New York - Upstate Medical University