An interventional study of Mirror Therapy and Sham Intervention in Total Knee Arthroplasty Recovery, sponsored by State University of New York - Upstate Medical University. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-02.
Sponsored by State University of New York - Upstate Medical University · Not applicable, Interventional, and Treatment
The investigators are looking to see if using a mirror during knee exercises after a knee replacement helps participants with less pain and/or better knee range of motion.
Purpose: To examine the effectiveness of mirror therapy combined with standard care physical therapy on knee range of motion (ROM), pain levels, and physical function in individuals following a total knee arthroplasty (TKA).
Background: Following a TKA, patients often present with numerous impairments including joint stiffness, pain, decreased strength, and impaired mobility. These limitations can inhibit functional progress during rehabilitation and recovery. Mirror therapy is a potential treatment option that may assist in reducing these impairments and improving recovery following TKA.
Study Activities: Active and sham group activities will add-on to the physical therapy session and are considered part of standard care, with no change to the current billing process. Both groups will participate in ROM activities, consistent with standard PT care, as part of a billable treatment. The active group with do standard practice ROM activities while looking at a mirror and the sham group will perform ROM activities without a mirror.
Interventions:
Data Analysis: Demographic information will be reported using descriptive statistics. Analyses will use linear mixed-effects models with fixed effects for Group, Time, and the Group × Time interaction, and with subject-level random effects to account for repeated measures. The primary inference will be the Group × Time interaction.
10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.
This study's planned enrollment of 30 is below the median of 66 across 8,493 interventional studies indexed under Pain.
Browse Pain studies →State University of New York - Upstate Medical University is the lead sponsor of 157 studies on the registry; 18 are open to participants now.
Of its 11 completed or terminated interventional studies of FDA-regulated products, 4 (36%) have results posted.
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Exclusion Criteria:
Subjects will participate in ROM activities, consistent with standard PT care, without a mirror
Other: Sham Intervention
Subjects will participate in ROM activities, consistent with standard PT care, with a mirror
Other: Mirror Therapy
Using a mirror while participating in ROM activities.
Using a covered mirror, unable to see reflection. subject will perform all ROM activities
Pain NRS (Pain Numerical Rating Scale)
Subject rates pain from 0-10 with 0 being no pain and 10 being the worst pain
Time frame: Every visit, visits 1, 2, 3, 4, 5, 6, 7 & 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.
Knee Flexion and Extension Goniometry
A measurement of knee flexion and knee extension, using a goniometer, will be completed.
Time frame: Every visit, visits 1, 2, 3, 4, 5, 6, 7 & 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.
Gait Speed
Subject's gait speed will be measured in meters/second.
Time frame: Visit 1 and visit 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.
Knee Injury and Osteoarthritis Outcome Score, Junior (KOOS Jr)
Knee Injury and Osteoarthritis Outcome Score, Junior (KOOS Jr) is a short, 7-question survey used by doctors to quickly assess a patient's knee pain, stiffness, and daily function. The raw score is converted to a 0-100 scale with a score of 0 = total disability and 100 = full function without pain.
Time frame: Visit 1 and visit 8. Visits start within 14 days of the TKA and occur a total of 8 times within a 4 weeks time frame.
No study locations are listed for this record.
Plan to share: No
Start is estimated for Feb 2026; primary completion for Aug 2026, 6 months later.
Of 3,731 non-industry interventional studies with no phase under Pain, half reached primary completion within 10 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 23. This study's planned 6 months is below that.
Counting every sponsor, half of 3,830 studies reached it within 10 months; a quarter within 4 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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State University of New York - Upstate Medical University →