An interventional study of Inspiratory muscle training in Healthy and Heart Failure, sponsored by Mayo Clinic. Recruiting at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-17.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Other
The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.
5,701 studies on the registry are indexed under Heart Failure; 1,220 are open to participants now.
This study's planned enrollment of 42 is below the median of 72 across 3,736 interventional studies indexed under Heart Failure.
Browse Heart Failure studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria - Heart Failure Group:
Inclusion Criteria - Healthy Control Group:
Exclusion Criteria:
Perform inspiratory muscle training at 2% maximal inspiratory pressure for 12 weeks.
Device: Inspiratory muscle training
Perform inspiratory muscle training at 40% maximal inspiratory pressure for 12 weeks.
Device: Inspiratory muscle training
Inspiratory muscle training for 12 weeks at 40% maximal inspiratory pressure
Blood pressure response
Mean arterial pressure
Time frame: baseline and 12 week follow up
Change in blood flow response
respiratory muscle blood flow
Time frame: baseline and 12 week follow up
Change in limb vascular resistance response
Limb vascular resistance
Time frame: baseline and 12 week follow up
Plan to share: No
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