CClinicalTrials.gg
Active, not recruitingNCT02047396Updated Feb 23, 2026

Ventricular Remodeling and Heart Failure After Myocardial Infarction: A Community Study

An observational study in Heart Failure and Myocardial Infarction, sponsored by Mayo Clinic. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-23.

Sponsored by Mayo Clinic · Observational

Study type
Observational
Model
Ecologic or community
Time perspective
Prospective
Enrollment
1,599
Ages
18 Years and older
Sex
All
01

Study summary

To comprehensively characterize Left Ventricular (LV) remodeling after Myocardial Infarction (MI) in the community, study the association between patterns of remodeling and biological pathways and examine the association between the predictors of remodeling and heart failure after Myocardial Infarction.

02

Conditions studied

  • Heart Failure
  • Myocardial Infarction
03

In context

Heart Failure

5,697 studies on the registry are indexed under Heart Failure; 1,219 are open to participants now.

This study's enrollment of 1,599 is above the median of 200 across 1,678 observational studies indexed under Heart Failure.

Browse Heart Failure studies →

Lead sponsor

Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.

Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Subjects in the 7 County area who are admitted to the Mayo Clinic Hospitals in Rochester, Minnesota who have their first myocardial infarction and are willing to have blood drawn and return for an echocardiogram in 3 months.

Inclusion criteria

  1. Hospitalized patients with a clinical diagnosis of Myocardial Infarction.
  2. Residents of Olmsted, Dodge, Goodhue, Wabasha, Winona, Fillmore and Mower Counties.
  3. Able to provide informed consent.

Exclusion criteria

Exclusion Criteria:

  1. Previous clinical diagnosis of Myocardial Infarction
  2. Previous diagnosis of Heart Failure and/or Cardiomyopathy
  3. Diagnosis of Apical Ballooning Syndrome
  4. Planned Coronary Artery Bypass Graft (CABG) during index hospitalization
  5. Unable to provide informed consent
05

Study design

Observational model
Ecologic or community
Time perspective
Prospective
Enrollment
1,599 participants (actual)
Patient registry
No
Biospecimen retention
Samples without dna

Groups and cohorts

  • Myocardial Infarction subjects

    Subjects with first Myocardial Infarction presenting to one of the Mayo Clinic Hospitals in Rochester, Minnesota.

06

What researchers measure

Primary outcomes

  1. Heart Failure

    Development of Heart Failure post Myocardial Infarction

    Time frame: 5 years

Secondary outcomes

  1. Death

    All cause mortality post Myocardial Infarction

    Time frame: 5 years

07

Study locations

1 site
  • Mayo Clinic
    Rochester, Minnesota 55905, United States
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02047396
Lead sponsor
Mayo Clinic
Collaborators
National Heart, Lung, and Blood Institute (NHLBI)
Responsible party
Suzette J. Bielinski (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Jan 28, 2014
Start date
Jan 2014
Primary completion
Aug 31, 2018
Completion
Jan 2030 (estimated)
Last update
Feb 23, 2026

Study contacts

Suzette Bielinski, PhD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in Feb 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion