Clinical trials in Botswana
133 studies list at least one site in Botswana. 16 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-11-05.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Most studied here
Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (28) · Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (12) · Harvard School of Public Health (HSPH) (11) · University of Pennsylvania (11) · Centers for Disease Control and Prevention (7) · University of Botswana (4) · International Maternal Pediatric Adolescent AIDS Clinical Trials Group (4) · COVID-19 Prevention Network (3)
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
Results posted1
- BAPS in Botswana: The Thotloetso TrialOct 27, 2026NCT04532970
Stopped1
- Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisSuspendedNov 2, 2026NCT06192160
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 133 — search for more.
- A Study of Daily Rifapentine Combined With Isoniazid (1HP) for Tuberculosis Prevention in Children Less Than 13 Years of Age With and Without HIVRecruitingNCT07124559Phase 1/2
- C2001P-CS3: Testing the Feasibility of Different HPV Screening and Care Strategies for Women Living With HIVNot yet recruitingNCT07576842Not applicable
- A Clinical Study to Assess the Efficacy of Weekly Doxycycline Prophylaxis to Reduce Bacterial Sexually Transmitted Infections (STI) in Young African WomenNot yet recruitingNCT07884240Phase 3
- Pharmacokinetic Study of Long-acting Antiretrovirals and Contraceptives in HIVRecruitingNCT07516548
- DYnamic decisioN Support for IntegrAting PrEP in Clinics for Young People in Alabama and BotswanaNot yet recruitingNCT07597824
- Low INR to Minimize Bleeding With Mechanical Valves TrialRecruitingNCT03636295Phase 3
- A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)Not yet recruitingNCT07595042Phase 2
- Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in BotswanaRecruitingNCT05952141Not applicable
- Lung Health and the Microbiome Among Adults in Botswana: the Go-hema CohortRecruitingNCT07699614
- Healthy Expectancy Through Routine Antenatal STI ScreeningRecruitingNCT07458802Not applicable
- STI Testing to Enhance PrEP Use in PregnancyRecruitingNCT06919614Phase 3
- RCT of an Intersectional Stigma Intervention to Sustain Viral Suppression Among Women Living With Serious Mental Illness and HIV in BotswanaRecruitingNCT05807867Not applicable
- Botswana Smoking and Abstinence Reinforcement TrialEnrolling by invitationNCT05694637Phase 4
- Assessment of a Brief Post Traumatic Stress Disorder Intervention for Use in BotswanaRecruitingNCT04426448Not applicable
- Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Population in BotswanaRecruitingNCT06399146Not applicable
- Acute Optic Neuritis Network: an International Study That Invesitages Subjects With a First-ever Episode of Acute Inflammation of the Optic NerveRecruitingNCT05605951
- Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus)Active, not recruitingNCT06134362Phase 3
- Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of AgeActive, not recruitingNCT05660980Phase 1/2
- Trial of Novel Regimens for the Treatment of Pulmonary TuberculosisSuspendedNCT06192160Phase 2
- Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis PatientsActive, not recruitingNCT03568383Phase 3
- BAPS in Botswana: The Thotloetso TrialCompletedNCT04532970Not applicable
- Surveillance of Healthcare-associated Infections & Antimicrobial ResistanceCompletedNCT05734391
- Linezolid Dosing Strategies in Drug-Resistant TBCompletedNCT05007821Phase 2
- Cash Transfers to Pregnant Women With HIVActive, not recruitingNCT07226492Not applicable
- The Tatelo Plus StudyActive, not recruitingNCT06508749Phase 1/2
- Increasing Access to Multiple Micronutrient Supplementation - A Pilot Intervention at up to 15 Clinics in BotswanaCompletedNCT05703373Not applicable
- Antiretrovirals Combined With Antibodies for HIV-1 Cure In AfricaActive, not recruitingNCT06205602Phase 2
- Pausing Antiretroviral Treatment Under Structured EvaluationCompletedNCT06031272Phase 1
- Stakeholder-Informed RSV Prevention Economic Model in BotswanaActive, not recruitingNCT07756528
- Robot-Assisted Rehabilitation After HIV-Associated Stroke: BotswanaActive, not recruitingNCT04488250Not applicable
- Evaluating the Efficacy and Safety of Dolutegravir-Containing Versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and Their InfantsCompletedNCT03048422Phase 3
- Tshireletso: Safety, Efficacy and Feasibility of Cabotegravir-LA PrEP in a Breastfeeding Population in BotswanaActive, not recruitingNCT05986084Phase 4
- Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIVSuspendedNCT06705478Phase 2
- POC HIV Testing and Early DTG Use for InfantsActive, not recruitingNCT05393193Phase 4
- Study of Limited Versus Continuous Isoniazid Tuberculosis Preventive Therapy in HIV-infected Persons in BotswanaCompletedNCT00164281Phase 4
- Group-Based Intervention to Improve Mental Health and Adherence Among Youth Living With HIV in Low Resource SettingsTerminatedNCT04024488Not applicable
- Integrating Hypertension and Cardiovascular Diseases Care Into Existing HIV Services Package in Botswana (InterCARE)CompletedNCT05414526Not applicable
- Dual bNAb Treatment in ChildrenCompletedNCT03707977Phase 1/2
- Primary HPV-based Cervical Cancer Screening Algorithms in BotswanaActive, not recruitingNCT04242823Not applicable
- Efficacy Study of COVID-19 mRNA Vaccine in Regions With SARS-CoV-2 Variants of ConcernCompletedNCT05168813Phase 2/3
- Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP StudyCompletedNCT04860323Not applicable
- Early Infant HIV Treatment in BotswanaActive, not recruitingNCT02369406Phase 2/3
- Dolutegravir Study in HIV-1 Participants Completing IMPAACT Studies P1093 and P2019CompletedNCT03016533Phase 3
- Prevalence of Epstein-Barr Virus InfectionActive, not recruitingNCT06444152
- More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and AdolescentsCompletedNCT03497676Phase 1/2
- Post-Trial Tuberculosis Case Finding: A Substudy of CoVPN 3008CompletedNCT06585683
- Long-Term Clinical, Immunologic, and Virologic Profiles of Children Who Received Early Treatment for HIVCompletedNCT05154513
- Efficacy of Human Papillomavirus (HPV) Vaccination to Prevent Infection Among Women Living With HIV.Active, not recruitingNCT06436274Phase 4
- A Multilevel Intervention to Improve Timely Cancer Detection and Treatment InitiationActive, not recruitingNCT04141449Phase 2
- Factors Influencing Tamoxifen Adherence in Women With Breast Cancer Receiving Tamoxifen in Botswana.TerminatedNCT06660030