Tyrosine Kinase Inhibitors: all 10,469 studies that test it

Page 43 of 105. Open to participants first (1,907), then studies with results posted, then the rest; newest registration first within each.

• A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on ErlotinibTerminatedNCT00750698Phase 2Results posted
• Maintenance of Tarceva (Erlotinib) in Patients With Locally Advanced Head and Neck CancerTerminatedNCT00750555Phase 2Results posted
• Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial CancerCompletedNCT00749892Phase 2Results posted
• Phase II Trial of BIBW 2992 (Afatinib) in Genetically Pre-screened Cancers With EGFR and/or HER2 Gene Amplification.TerminatedNCT00748709Phase 2Results posted
• Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate CancerCompletedNCT00744497Phase 3Results posted
• Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast CancerCompletedNCT00741260Phase 1/2Results posted
• Phase II Study of Erlotinib, an EGFR Inhibitor in Metastatic EGFR-positive 'Triple Receptor-negative' Breast CancerTerminatedNCT00739063Phase 2Results posted
• Pemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung CancerTerminatedNCT00738881Phase 3Results posted
• Saracatinib in Treating Patients With Previously Treated Metastatic Pancreatic CancerCompletedNCT00735917Phase 2Results posted
• Trial Of AG-013736, Cisplatin, And Gemcitabine For Patients With Squamous Non-Small Cell Lung CancerCompletedNCT00735904Phase 2Results posted
• Phase I/II Trial of Radiation, Avastin and Tarceva for Pancreatic AdenocarcinomaCompletedNCT00735306Phase 1Results posted
• Multimodality Phase II Study in Prostate CancerTerminatedNCT00734851Phase 2Results posted
• Gemcitabine and Erlotinib Before and After Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed by SurgeryCompletedNCT00733746Phase 2Results posted
• Nab-Paclitaxel and Bevacizumab Followed By Bevacizumab and Erlotinib in Metastatic Breast CancerCompletedNCT00733408Phase 2Results posted
• An Extension to Study MD7108240CompletedNCT00733304Phase 2Results posted
• A Safety Study Of Sunitinib In Combination With Pemetrexed In Patients With Advanced Solid MalignanciesCompletedNCT00732992Phase 1Results posted
• Pazopanib in Previously Treated Patients With Metastatic Renal Cell CarcinomaCompletedNCT00731211Phase 2Results posted
• Single-arm Trial of BIBW 2992 (Afatinib) in Demographically and Genotypically Selected NSCLC PatientsCompletedNCT00730925Phase 2Results posted
• Sutent + Taxol for Advanced Esophageal CancerCompletedNCT00730353Phase 2Results posted
• Study Of CP-751,871 In Combination With Sunitinib In Patients With Advanced Solid TumorsTerminatedNCT00729833Phase 1Results posted
• A Study To Test The Impact Of PF- 00299804 On How The Body Handles Dextromethorphan In Cancer PatientsCompletedNCT00728468Phase 1Results posted
• Sorafenib in Treating Patients With Locally Advanced or Metastatic Kidney CancerTerminatedNCT00727532Not applicableResults posted
• BIBW 2992 (Afatinib) With or Without Daily Temozolomide in the Treatment of Patients With Recurrent Malignant GliomaCompletedNCT00727506Phase 2Results posted
• Sorafenib, Cisplatin, and Etoposide in Treating Patients With Extensive-Stage Small Cell Lung CancerTerminatedNCT00726986Phase 2Results posted
• A Study In Patients With Advanced Solid TumorCompletedNCT00726752Phase 1Results posted
• A Phase II Study of GSK1363089 (Formerly XL880) for Papillary Renal-Cell Carcinoma (PRC)CompletedNCT00726323Phase 2Results posted
• Study to Determine the Safety and Efficacy of INCB018424 in Patients With Polycythemia Vera or Essential ThrombocythemiaTerminatedNCT00726232Phase 2Results posted
• Phase 2 Study of GSK1363089 (Formerly XL880) in Adults With Squamous Cell Cancer of the Head and NeckCompletedNCT00725764Phase 2Results posted
• Study of GSK1363089 in Metastatic Gastric CancerCompletedNCT00725712Phase 2Results posted
• A Long-Term Study of the Effects of Orally Administered SAR302503 in Patients With MyelofibrosisCompletedNCT00724334Phase 1/2Results posted
• Sorafenib and Fulvestrant in Treating Patients With Locally Advanced or Metastatic Breast Cancer That Did Not Respond to Aromatase Inhibitor TherapyTerminatedNCT00722072Phase 2Results posted
• Novel Capecitabine Dosing Schedule in Combination With Lapatinib, Based on the Norton-Simon Mathematical Method in Patients With HER2 Overexpressed/Amplified, Trastuzumab (Herceptin) -Refractory, Metastatic Breast CancerCompletedNCT00721630Phase 2Results posted
• Pazopanib Versus Sunitinib in the Treatment of Locally Advanced and/or Metastatic Renal Cell CarcinomaCompletedNCT00720941Phase 3Results posted
• Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or GliosarcomaCompletedNCT00720356Phase 2Results posted
• Erlotinib, Docetaxel, and Radiation Therapy in Stage III or Stage IV Squamous Cell Carcinoma of the Head and NeckCompletedNCT00720304Phase 2Results posted
• Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic LeukemiaCompletedNCT00720109Phase 2/3Results posted
• Chemotherapy and Radiation Therapy (RT) With or Without Vandetanib in Treating Patients With High-Risk Stage III or Stage IV Head and Neck CancerTerminatedNCT00720083Phase 2Results posted
• Saracatinib in Treating Patients With Relapsed or Refractory Thymoma or Thymic CancerTerminatedNCT00718809Phase 2Results posted
• Cetuximab in Patients With Lung Adenocarcinoma Receiving Erlotinib That Have Developed "Acquired Resistance" to ErlotinibCompletedNCT00716456Phase 1/2Results posted
• Study to Determine the Maximum Tolerated Dose of BIBW 2992 (Afatinib) When Combined With Cisplatin/Paclitaxel or Cisplatin/5-FU in Patients With Advanced Solid TumoursCompletedNCT00716417Phase 1Results posted
• A Phase I/II Open Label Extension Study of BIBF 1120 Administered Orally Once or Twice Daily to Establish Safety, Pharmacokinetics and Efficacy in Patients With Advanced Solid Tumours and Clinical Benefit From Previous Therapy With BIBF 1120CompletedNCT00715403Phase 1Results posted
• Gemcitabine and Split-dose Cisplatin (GC) Plus Sorafenib in Chemotherapy-naïve Patients With Locally Advanced or Metastatic Urothelial CarcinomaTerminatedNCT00714948Phase 2Results posted
• LUX-Lung 4: BIBW 2992 (Afatinib) Phase I Trial in Advanced Non Small Cell Lung Cancer Patients & Phase II Trial in Non Small Cell Lung Cancer Patients Failing Erlotinib or GefitinibCompletedNCT00711594Phase 2Results posted
• A Randomised Placebo-Controlled Phase II Study of Continuous Maintenance Treatment With BIBF 1120 Following Chemotherapy in Patients With Relapsed Ovarian CancerCompletedNCT00710762Phase 2Results posted
• Phase II Lapatinib Plus Nab-Paclitaxel As First And Second Line Therapy In her2+ MBCCompletedNCT00709761Phase 2Results posted
• Lapatinib + Vinorelbine in ErbB2 Overexpressing, First or Second Line Metastatic Breast Cancer SubjectsTerminatedNCT00709618Phase 2Results posted
• BIBW 2992 and Letrozole in Hormonoresistant Metastatic Breast CancerCompletedNCT00708214Phase 2Results posted
• Safety And Efficacy Study Of Sunitinib Malate As First-Line Systemic Therapy In Chinese Patients With Metastatic Renal Cell CarcinomaCompletedNCT00706706Phase 4Results posted
• Neoadjuvant Dasatinib and Radical Cystectomy for Transitional Cell Carcinoma of the BladderCompletedNCT00706641Not applicableResults posted
• A Multi-centre 3-arm Randomised Phase II Trial of BIBF 1120 Versus BIBW 2992 Versus Sequential Administration of BIBF 1120 and BIBW 2992 in Patients With Hormone-resistant Prostate CancerCompletedNCT00706628Phase 2Results posted
• A Study of PF-04217903 in Patients With Advanced CancerTerminatedNCT00706355Phase 1Results posted
• Pilot Study of Fostamatinib Disodium/R935788 for the Treatment of Adult Refractory Immune Thrombocytopenic Purpura (ITP)CompletedNCT00706342Phase 2Results posted
• Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast CancerCompletedNCT00706030Phase 1/2Results posted
• Study of CGC-11047 When Used in Individual Combinations With 1) Gemcitabine or 2) Docetaxel or 3) Bevacizumab or 4) Erlotinib or 5) Cisplatin or 6) 5-Flurouracil or 7) Sunitinib in Patients With Advanced Solid Tumors or LymphomaCompletedNCT00705874Phase 1Results posted
• Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid CancerCompletedNCT00704730Phase 3Results posted
• Study of XL184 (Cabozantinib) in Adults With Glioblastoma MultiformeCompletedNCT00704288Phase 2Results posted
• Sunitinib in Treating Patients With Relapsed or Refractory Esophageal or Gastroesophageal Junction CancerCompletedNCT00702884Phase 2Results posted
• Imatinib Mesylate to Treat Skin Changes in Patients With Chronic Graft-Versus-Host DiseaseCompletedNCT00702689Phase 2Results posted
• Nilotinib and Imatinib Mesylate After Donor Stem Cell Transplant in Treating Patients With ALL or CMLCompletedNCT00702403Phase 1/2Results posted
• A Study of First Line Treatment With Tarceva (Erlotinib) in Combination With Gemcitabine in Patients With Unresectable Advanced and/or Metastatic Non-Small Cell Lung CancerCompletedNCT00701558Phase 2Results posted
• Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By SurgeryCompletedNCT00700882Phase 2Results posted
• Study Of Sunitinib Malate Versus Sorafenib In Patients With Inoperable Liver CancerTerminatedNCT00699374Phase 3Results posted
• Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung CancerCompletedNCT00698815Phase 2Results posted
• Study of Gemcitabine and Erlotinib Plus Sorafenib (GES) in Metastatic Pancreatic CancerCompletedNCT00696696Phase 2Results posted
• Randomized Phase II Trial of Letrozole With or Without Dasatinib as First and Second-line Treatment for Hormone Receptor-positive, HER2-negative Post-menopausal Breast Cancer That is Unresectable, Locally Recurrent or MetastaticCompletedNCT00696072Phase 2Results posted
• Irinotecan, Carboplatin, and Sunitinib in First Line Extensive-Stage Small Cell Lung CancerCompletedNCT00695292Phase 2Results posted
• Sunitinib for Metastatic Renal Cell Cancer With Imaging Biomarker Assessments for the Early Prediction of Tumor ResponseCompletedNCT00694096Phase 1Results posted
• Sunitinib Malate as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer Previously Treated With Combination ChemotherapyCompletedNCT00693992Phase 3Results posted
• Sorafenib as Adjuvant Treatment in the Prevention Of Recurrence of Hepatocellular Carcinoma (STORM)CompletedNCT00692770Phase 3Results posted
• Evaluation Of Hepatic Impairment On AG-013736 PharmacokineticsCompletedNCT00692341Phase 1Results posted
• Sorafenib, Lenalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple MyelomaTerminatedNCT00687674Phase 1Results posted
• Study of Vandetanib Combined With Chemotherapy to Treat Advanced Non-small Cell Lung CancerCompletedNCT00687297Phase 2Results posted
• Comparison Of 5 CP-690,550 Doses Vs. Placebo, For The Treatment Of Rheumatoid Arthritis In JapanCompletedNCT00687193Phase 2Results posted
• Trial Assessing Zactima Against Placebo in Prostate Cancer Subjects Undergoing Intermittent Androgen Deprivation Hormonal TherapyTerminatedNCT00686036Phase 2Results posted
• Gleevec in Relapsed/Refractory T Cell Non-Hodgkin's LymphomaCompletedNCT00684411Phase 2Results posted
• Docetaxel With or Without Vandetanib in Treating Patients With Metastatic Stomach Cancer or Gastroesophageal Junction CancerTerminatedNCT00683787Phase 2Results posted
• LOGiC - Lapatinib Optimization Study in ErbB2 (HER2) Positive Gastric Cancer: A Phase III Global, Blinded Study Designed to Evaluate Clinical Endpoints and Safety of Chemotherapy Plus LapatinibCompletedNCT00680901Phase 3Results posted
• Topical CP-690,550 For Chronic Plaque PsoriasisCompletedNCT00678561Phase 2Results posted
• Axitinib (AG 013736) As Second Line Therapy For Metastatic Renal Cell CancerCompletedNCT00678392Phase 3Results posted
• A Study to Assess Sorafenib Alone and in Combination With Low-Dose Interferon Following Unsuccessful Treatment With Sunitinib in Patients With Advanced Renal Cell Cancer.TerminatedNCT00678288Phase 2Results posted
• Effectiveness and Safety of 3 Dosing Regimens of CP-690,550 to Placebo in Subjects With Moderate to Severe Chronic Plaque PsoriasisCompletedNCT00678210Phase 2Results posted
• Pilot Study of Imatinib Mesylate to Treat Nephrogenic Systemic FibrosisCompletedNCT00677092Phase 2Results posted
• Sunitinib Plus Prednisone In Patients With Metastatic Castration-Resistant Prostate Cancer After Failure Of Docetaxel ChemotherapyTerminatedNCT00676650Phase 3Results posted
• A Biomarker Identification Trial of Tarceva (Erlotinib) in Patients With Advanced Pancreatic CancerCompletedNCT00674973Phase 2Results posted
• INCB018424 in Patients With Advanced Hematologic MalignanciesCompletedNCT00674479Phase 2Results posted
• Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau SyndromeTerminatedNCT00673816Phase 1/2Results posted
• Pilot Trial of "Chemo-Switch" Regimen to Treat Advanced MelanomaTerminatedNCT00673361Phase 2Results posted
• Study of Sunitinib Malate in Patients With Newly Diagnosed Prostate Cancer Prior to ProstatectomyCompletedNCT00672594Phase 2Results posted
• Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma MultiformeCompletedNCT00672243Phase 2Results posted
• Phase (Ph) II Bevacizumab + Erlotinib for Patients (Pts) With Recurrent Malignant Glioma (MG)CompletedNCT00671970Phase 2Results posted
• A Phase II Evaluation of Dasatinib (Sprycel®, NSC #732517) in the Treatment of Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal CarcinomaCompletedNCT00671788Phase 2Results posted
• Saracatinib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By SurgeryCompletedNCT00669019Phase 2Results posted
• Study Of Sunitinib With FOLFIRI In Colorectal CancerCompletedNCT00668863Phase 2Results posted
• Sutent Adjunctive Treatment of Differentiated Thyroid CancerCompletedNCT00668811Phase 2Results posted
• Study of Temzolomide and Gleevec in Advanced MelanomaTerminatedNCT00667953Phase 1/2Results posted
• Tandutinib Plus Bevacizumab to Treat Recurrent Brain TumorsCompletedNCT00667394Phase 2Results posted
• Chemotherapy and Lapatinib or Trastuzumab in Treating Women With HER2/Neu-Positive Metastatic Breast CancerCompletedNCT00667251Phase 3Results posted
• Study Of PF-00562271, Including Patients With Pancreatic, Head And Neck, Prostatic NeoplasmsCompletedNCT00666926Phase 1Results posted
• Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid ArthritisCompletedNCT00665925Phase 2Results posted
• Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-3)CompletedNCT00665626Phase 2Results posted

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