Tyrosine Kinase Inhibitors: all 10,469 studies that test it

Page 35 of 105. Open to participants first (1,907), then studies with results posted, then the rest; newest registration first within each.

• Tofacitinib Ointment For Chronic Plaque PsoriasisCompletedNCT01831466Phase 2Results posted
• Sunitinib in Never-Smokers With Lung AdenocarcinomaCompletedNCT01829217Phase 2Results posted
• LDK378 Versus Chemotherapy in ALK Rearranged (ALK Positive) Patients Previously Treated With Chemotherapy (Platinum Doublet) and CrizotinibCompletedNCT01828112Phase 3Results posted
• LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung CancerCompletedNCT01828099Phase 3Results posted
• Phase III Trial Evaluating the Effectiveness of a Dose Adjustment of Imatinib Mesylate on the Molecular ResponseTerminatedNCT01827930Phase 3Results posted
• MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene VariationsCompletedNCT01827384Phase 2Results posted
• Neratinib With and Without Temsirolimus for Patients With HER2 Activating Mutations in Non-Small Cell Lung CancerCompletedNCT01827267Phase 2Results posted
• Paclitaxel With Trastuzumab and Lapatinib in HER2-Positive Early Stage Breast CancerCompletedNCT01827163Phase 2Results posted
• A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF MelanomaTerminatedNCT01826448Phase 1Results posted
• Docetaxel With or Without FGFR Inhibitor AZD4547 in Treating Patients With Recurrent Non-Small Cell Lung CancerCompletedNCT01824901Phase 1/2Results posted
• Afatinib After Chemoradiation and Surgery in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck at High-Risk of RecurrenceTerminatedNCT01824823Phase 2Results posted
• An Open-Label Study of Ruxolitinib Given With Chemotherapy in Patients With Advanced Solid TumorsTerminatedNCT01822756Phase 1Results posted
• Cabozantinib S-Malate in Treating Patients With Advanced Solid Tumors and Human Immunodeficiency VirusCompletedNCT01822522Phase 1Results posted
• Erlotinib Hydrochloride or Crizotinib and Chemoradiation Therapy in Treating Patients With Stage III Non-small Cell Lung CancerTerminatedNCT01822496Phase 2Results posted
• Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade GliomaCompletedNCT01817751Phase 2Results posted
• A Study Evaluating The Efficacy And Safety Of CP-690,550 In Asian Subjects With Moderate To Severe Plaque PsoriasisCompletedNCT01815424Phase 3Results posted
• ADAM-Afatinib Diarrhea Assessment and ManagementCompletedNCT01814553Phase 3Results posted
• Ponatinib in Advanced NSCLC w/ RET TranslocationsCompletedNCT01813734Phase 2Results posted
• Cabozantinib-S-Malate in Treating Patients With Hormone-Resistant Metastatic Prostate CancerCompletedNCT01812668Not applicableResults posted
• Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid CancerCompletedNCT01811212Phase 2Results posted
• A Study of Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer Who Have Received Two or More Prior HER2 Directed Regimens in the Metastatic SettingCompletedNCT01808573Phase 3Results posted
• Phase II Trial of Tivozanib in Advanced Hepatocellular CancerTerminatedNCT01807156Phase 2Results posted
• Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01806571Phase 2Results posted
• Randomized Phase 2 Trial of Axitinib and TRC105 Versus Axitinib Alone in Patients Renal Cell CarcinomaTerminatedNCT01806064Phase 1/2Results posted
• AZD9291 First Time In Patients Ascending Dose StudyCompletedNCT01802632Phase 1/2Results posted
• A Study of Alectinib (RO5424802) in Participants With Non-Small Cell Lung Cancer Who Have Anaplastic Lymphoma Kinase (ALK) Mutation and Failed Crizotinib TreatmentCompletedNCT01801111Phase 1/2Results posted
• Entospletinib in Combination With Idelalisib in Adults With Relapsed or Refractory Hematologic MalignanciesTerminatedNCT01796470Phase 2Results posted
• A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed GlioblastomaCompletedNCT01790503Phase 1/2Results posted
• Ruxolitinib Prior to Transplant in Patients With MyelofibrosisTerminatedNCT01790295Phase 2Results posted
• A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MFCompletedNCT01787552Phase 1/2Results posted
• Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing SpondylitisCompletedNCT01786668Phase 2Results posted
• Nilotinib Treatment-free Remission Study in CML (Chronic Myeloid Leukemia) PatientsCompletedNCT01784068Phase 2Results posted
• A Dose Ranging Study to Evaluate the Safety and Efficacy of GSK2586184 in Patients With Chronic Plaque PsoriasisCompletedNCT01782664Phase 2Results posted
• A Phase II Study of Tivozanib in Patients With Metastatic and Non-resectable Soft Tissue SarcomasCompletedNCT01782313Phase 2Results posted
• Imatinib Treatment in Recent Onset Type 1 Diabetes MellitusCompletedNCT01781975Phase 2Results posted
• A Study of the Bruton's Tyrosine Kinase Inhibitor Ibrutinib Given in Combination With Bendamustine and Rituximab in Patients With Newly Diagnosed Mantle Cell LymphomaCompletedNCT01776840Phase 3Results posted
• A Sequential Two-Stage Dose Escalation Study to Evaluate the Safety and Efficacy of RuxolitinibCompletedNCT01776723Phase 1/2Results posted
• Sorafenib + mFOLFOX for Hepatocellular CarcinomaCompletedNCT01775501Phase 2Results posted
• ARCHER1050: A Study of Dacomitinib vs. Gefitinib in 1st-Line Treatment Of Advanced NSCLC.CompletedNCT01774721Phase 3Results posted
• Study of Regorafenib After Sorafenib in Patients With Hepatocellular CarcinomaCompletedNCT01774344Phase 3Results posted
• Pacritinib Versus Best Available Therapy to Treat MyelofibrosisTerminatedNCT01773187Phase 3Results posted
• Relative Bioavailability of a Single Dose of Nintedanib Given Alone and in Combination With Multiple Doses of RifampicinCompletedNCT01770392Phase 1Results posted
• Study of 5-FU, Oxaliplatin, & Lapatinib Combined With Radiation Therapy to Treat HER2 Positive Esophagogastric CancerTerminatedNCT01769508Phase 2Results posted
• Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney CancerCompletedNCT01767636Phase 2Results posted
• Ponatinib for Squamous Cell Lung and Head and Neck CancersTerminatedNCT01761747Phase 2/3Results posted
• A Multicenter, Open-Label, Phase 3 Trial to Compare the Efficacy and Safety of Lenvatinib (E7080) Versus Sorafenib in First-line Treatment of Participants With Unresectable Hepatocellular CarcinomaCompletedNCT01761266Phase 3Results posted
• Study of Tivantinib in Subjects With Inoperable Hepatocellular Carcinoma (HCC) Who Have Been Treated With One Prior TherapyCompletedNCT01755767Phase 3Results posted
• Cabozantinib for Adults With Advanced Soft Tissue SarcomaCompletedNCT01755195Phase 2Results posted
• A Study of Vitamin C in the Treatment of Liver Cancer to Determine if it is Safe and EffectiveCompletedNCT01754987Phase 1/2Results posted
• Dovitinib in Treating Patients With Recurrent or Progressive GlioblastomaCompletedNCT01753713Phase 2Results posted
• Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLLCompletedNCT01752426Phase 1/2Results posted
• AZD1775 for Advanced Solid TumorsCompletedNCT01748825Phase 1Results posted
• Tivozanib in Combination With Paclitaxel in Patients With Locally Recurrent or Metastatic Triple Negative Breast CancerTerminatedNCT01745367Phase 2Results posted
• Co-Administration Of Methotrexate And CP-690,550CompletedNCT01745055Phase 1Results posted
• A Multicenter Phase 2 Study of Ibrutinib in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) With 17p DeletionCompletedNCT01744691Phase 2Results posted
• A Study That Switched Patients From Imatinib to Nilotinib and Then Was Followed by Treatment CessationCompletedNCT01744665Phase 2Results posted
• Sandostatin LAR and Axitinib vs Pbo in Pnts With Advanced Well-differentiated Non-pancreatic Neuroendocrine CarcinomasCompletedNCT01744249Phase 2/3Results posted
• A Randomized Phase III Study to Assess the Effect of a Longer Duration of Consolidation Treatment With Nilotinib on TFR in CP CML.CompletedNCT01743989Phase 3Results posted
• CP-690,550 Thorough QTc StudyCompletedNCT01743677Phase 1Results posted
• Phase I Study of LDK378 in Pediatric, Malignancies With a Genetic Alteration in Anaplastic Lymphoma Kinase (ALK)CompletedNCT01742286Phase 1Results posted
• Pharmacokinetics Of CP-690,550 In Patients With Impaired Renal FunctionCompletedNCT01740362Phase 1Results posted
• Sunitinib Malate Related Fatigue in Patients With Metastatic Kidney CancerTerminatedNCT01740154Not applicableResults posted
• Cabozantinib for Metastatic Triple Negative BrCaCompletedNCT01738438Phase 2Results posted
• Study Efficacy and Safety of INC280 in Patients With Advanced Hepatocellular Carcinoma.TerminatedNCT01737827Phase 2Results posted
• Multiple Dose Escalation Study In Medically Stable Subjects With PsoriasisCompletedNCT01736696Phase 1Results posted
• Study to Allow Access to Nilotinib for Patients Who Are on Nilotinib Treatment in a Novartis-sponsored StudyCompletedNCT01735955Phase 4Results posted
• A Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC.TerminatedNCT01732640Phase 1/2Results posted
• Ruxolitinib Phosphate and Danazol in Treating Anemia in Patients With MyelofibrosisCompletedNCT01732445Phase 2Results posted
• Dovitinib in BCG Refractory Urothelial Carcinoma With FGFR3 Mutations or Over-expressionTerminatedNCT01732107Phase 2Results posted
• A Study of E7080 in Subjects With Advanced Thyroid CancerCompletedNCT01728623Phase 2Results posted
• Study of Dalantercept and Axitinib in Patients With Advanced Renal Cell CarcinomaTerminatedNCT01727336Phase 2Results posted
• Open-label Extension Study in Patients 65 Years or Older With Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaCompletedNCT01724346Phase 3Results posted
• Open-label Phase 3 BTK Inhibitor Ibrutinib vs Chlorambucil Patients 65 Years or Older With Treatment-naive CLL or SLLCompletedNCT01722487Phase 3Results posted
• Phase I/II Trial of AXL1717 in the Treatment of Recurrent Malignant AstrocytomasTerminatedNCT01721577Phase 1/2Results posted
• A Study in Moderate to Severe Rheumatoid Arthritis ParticipantsCompletedNCT01721057Phase 3Results posted
• A Moderate to Severe Rheumatoid Arthritis StudyCompletedNCT01721044Phase 3Results posted
• Study of ENMD-2076 in Patients With Advanced/Metastatic Soft Tissue SarcomaCompletedNCT01719744Phase 2Results posted
• Cabozantinib or Paclitaxel in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cavity CancerCompletedNCT01716715Phase 2Results posted
• The Effect of Sorafenib on Portal PressureCompletedNCT01714609Phase 2Results posted
• Ruxolitinib for Adult T-Cell LeukemiaTerminatedNCT01712659Phase 1/2Results posted
• TRYHARD: Radiation Therapy Plus Cisplatin With or Without Lapatinib in Treating Patients With Head and Neck Cancer.CompletedNCT01711658Phase 2Results posted
• A Study in Participants With Moderate to Severe Rheumatoid ArthritisCompletedNCT01711359Phase 3Results posted
• A Study in Moderate to Severe Rheumatoid ArthritisCompletedNCT01710358Phase 3Results posted
• Study Of The Mechanism Of Action Of CP-690,550 In The Skin Of Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01710046Phase 2Results posted
• A Study Of CP-690,550 In Stable Kidney Transplant PatientsCompletedNCT01710033Phase 1Results posted
• Pharmacokinetics And Dialysability Of CP-690,550 In Subjects With End-Stage Renal DiseaseCompletedNCT01710020Phase 1Results posted
• Cabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid TumorsCompletedNCT01709435Phase 1Results posted
• Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung CancerActive, not recruitingNCT01708954Phase 2Results posted
• Cabozantinib in Men With Castration-Resistant Prostate CancerTerminatedNCT01703065Phase 2Results posted
• Treatment-free Remission After Achieving Sustained MR4.5 on Nilotinib (ENESTop)CompletedNCT01698905Phase 2Results posted
• A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for NephrectomyCompletedNCT01693822Phase 2Results posted
• Panobinostat and Ruxolitinib In MyElofibrosis (PRIME Trial)CompletedNCT01693601Phase 1/2Results posted
• Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical TrialCompletedNCT01692496Phase 2Results posted
• Cabozantinib for Advanced Urothelial CancerCompletedNCT01688999Phase 2Results posted
• Tivantinib With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Locally Advanced Kidney Cancer That Cannot Be Removed by SurgeryCompletedNCT01688973Phase 2Results posted
• Lapatinib Ditosylate, Trastuzumab, Paclitaxel, and Surgery in Treating Patients With Breast CancerCompletedNCT01688609Phase 2Results posted
• LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung CancerCompletedNCT01685138Phase 2Results posted
• LDK378 in Adult Patients With ALK-activated NSCLC Previously Treated With Chemotherapy and CrizotinibCompletedNCT01685060Phase 2Results posted
• Cabozantinib Plus Docetaxel and Prednisone for Advanced Prostate CancerCompletedNCT01683994Phase 1/2Results posted
• A Study to Test Safety and Efficacy of Baricitinib in Participants With Diabetic Kidney DiseaseCompletedNCT01683409Phase 2Results posted

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