Tyrosine Kinase Inhibitors: all 10,469 studies that test it

Page 37 of 105. Open to participants first (1,907), then studies with results posted, then the rest; newest registration first within each.

• Phase II Axitinib (AG-013736) in Elderly Glioblastoma Multiforme (GBM) PatientsTerminatedNCT01508117Phase 2Results posted
• Study of Pazopanib in the Treatment of Surgically Unresectable or Metastatic LiposarcomaCompletedNCT01506596Phase 2Results posted
• Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid CancerCompletedNCT01502410Phase 2Results posted
• PET/CT Assessment of Tumor Perfusion in Patients With Renal Cell CarcinomaTerminatedNCT01502228Not applicableResults posted
• PCI-32765 for Special Cases of Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaActive, not recruitingNCT01500733Phase 2Results posted
• Long-Term Safety Study Of Tofacitinib In Patients With Juvenile Idiopathic ArthritisCompletedNCT01500551Phase 2/3Results posted
• Study to Learn if 200mg Test Drug (Fostamatinib) Helps People With Large B-Cell Lymphoma,a Type of Blood CancerCompletedNCT01499303Phase 2Results posted
• Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast CancerTerminatedNCT01499160Phase 2Results posted
• Pilot Study of PLX3397 in Patients With Advanced Castration-Resistant Prostate Cancer (CRPC)TerminatedNCT01499043Phase 2Results posted
• Pazopanib in Combination With Capecitabine in Patients With Metastatic Breast CancerCompletedNCT01498458Phase 1Results posted
• An Open-Label, Phase I/II Study of Two Different Schedules of Dasatinib (Sprycel) and Decitabine (Dacogen) Used in Combination for Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia (Protocol CA180357)TerminatedNCT01498445Phase 1/2Results posted
• To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid CancerCompletedNCT01496313Phase 4Results posted
• HKI-272 for HER2-Positive Breast Cancer and Brain MetastasesCompletedNCT01494662Phase 2Results posted
• INC424 for Patients With Primary Myelofibrosis, Post Polycythemia Myelofibrosis or Post-essential Thrombocythemia Myelofibrosis.CompletedNCT01493414Phase 3Results posted
• Dasatinib in Advanced Squamous Cell Lung CancerTerminatedNCT01491633Phase 2Results posted
• A Trial of Single Agent Axitinib as Maintenance Therapy for Patients With First Line Metastatic Colorectal Cancer (mCRC)CompletedNCT01490866Phase 2Results posted
• A Phase 2b Study of Baricitinib in Participants With Moderate to Severe PsoriasisCompletedNCT01490632Phase 2Results posted
• Cetuximab and Dasatinib in Recurrent Squamous Cell CarcinomaTerminatedNCT01488318Phase 2Results posted
• Trial of Erlotinib and BKM120 in Patients With Advanced Non Small Cell Lung Cancer Previously Sensitive to ErlotinibCompletedNCT01487265Phase 2Results posted
• Dovitinib Plus an Aromatase Inhibitor for Metastatic Breast CancerTerminatedNCT01484041Phase 1/2Results posted
• A Study Combining mFOLFOX6 With Tivozanib or Bevacizumab in Patients With Metastatic Colorectal Cancer as First Line TherapyCompletedNCT01478594Phase 2Results posted
• Study of the Bruton's Tyrosine Kinase Inhibitor in Subjects With Relapsed or Relapsed and Refractory Multiple MyelomaCompletedNCT01478581Phase 2Results posted
• Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to ImatinibCompletedNCT01478373Phase 2Results posted
• Nivolumab (BMS-936558; MDX-1106) in Combination With Sunitinib, Pazopanib, or Ipilimumab in Subjects With Metastatic Renal Cell Carcinoma (RCC) (CheckMate 016)CompletedNCT01472081Phase 1Results posted
• Sorafenib Plus Capecitabine (SorCape) in Previously Treated Metastatic Colorectal CancerCompletedNCT01471353Phase 2Results posted
• Phase II Short-term Adjuvant Therapy and Biomarker Studies With Targeted Agents in Women With Estrogen Receptor Negative Breast CancerCompletedNCT01471106Phase 2Results posted
• Long-Term Study Of CP-690,550 In Subjects With Ulcerative ColitisCompletedNCT01470612Phase 3Results posted
• A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's DiseaseCompletedNCT01470599Phase 2Results posted
• Phase II Trial Evaluating Axitinib In Patients With Unresectable, Recurrent Or Metastatic Head And Neck CancerCompletedNCT01469546Phase 2Results posted
• First In Human, Phase 1 Study of AG013736 In Patients With Solid TumorsCompletedNCT01469052Phase 1Results posted
• Oral Baricitinib (LY3009104)Treatment in Japanese Participants With Active Rheumatoid Arthritis on Background Methotrexate TherapyCompletedNCT01469013Phase 2Results posted
• Pazopanib and ARQ 197 for Advanced Solid TumorsCompletedNCT01468922Phase 1Results posted
• Paclitaxel With or Without Pazopanib Hydrochloride in Treating Patients With Persistent or Recurrent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity CancerCompletedNCT01468909Phase 2Results posted
• Reversing Hormone Resistance in Advanced Breast Cancer With PazopanibCompletedNCT01466972Phase 2Results posted
• LUX-Lung 7: A Phase IIb Trial of Afatinib(BIBW2992) Versus Gefitinib for the Treatment of 1st Line EGFR Mutation Positive Adenocarcinoma of the LungCompletedNCT01466660Phase 2Results posted
• Cabozantinib in Advanced Pancreatic Neuroendocrine and Carcinoid TumorsCompletedNCT01466036Phase 2Results posted
• Study Of Dacomitinib (PF-00299804) In Advanced NSCLC Patients (Post Chemo Or Select First Line) To Evaluate Prophylactic Intervention On Derm And GI AEs And PROCompletedNCT01465802Phase 2Results posted
• A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative ColitisCompletedNCT01465763Phase 3Results posted
• Temozolomide and Pazopanib Hydrochloride in Treating Patients With Advanced Pancreatic Neuroendocrine Tumors That Cannot Be Removed By SurgeryCompletedNCT01465659Phase 1/2Results posted
• Orantinib In Combination With Transcatheter Arterial Chemoembolization In Patients With Unresectable Hepatocellular CarcinomaTerminatedNCT01465464Phase 3Results posted
• Sunitinib Malate in Treating Younger Patients With Recurrent, Refractory, or Progressive Malignant Glioma or EpendymomaCompletedNCT01462695Phase 2Results posted
• Pazopanib Hydrochloride in Treating Patients With Advanced AngiosarcomaCompletedNCT01462630Phase 2Results posted
• Pediatric Philadelphia Positive Acute Lymphoblastic LeukemiaCompletedNCT01460160Phase 2Results posted
• A Study To Evaluate Both The Efficacy and Safety Profile of CP-690,550 In Patients With Moderately to Severely Active Ulcerative ColitisCompletedNCT01458951Phase 3Results posted
• A Study Of Oral CP-690,550 As A Maintenance Therapy For Ulcerative ColitisCompletedNCT01458574Phase 3Results posted
• Efficacy and Safety of AZD4547 Versus Paclitaxel in Patients With Advanced Gastric or Gastro-oesophageal CancerTerminatedNCT01457846Phase 2Results posted
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-Tumor Activity of the Oral Anaplastic Lymphoma Kinase (ALK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Brigatinib (AP26113)CompletedNCT01449461Phase 1/2Results posted
• Tivantinib in Treating Patients With Relapsed, or Relapsed and Refractory Multiple MyelomaCompletedNCT01447914Phase 2Results posted
• Pazopanib Hydrochloride Followed by Chemotherapy and Surgery in Treating Patients With Soft Tissue SarcomaCompletedNCT01446809Not applicableResults posted
• Alternative Dosing Strategy of Ruxolitinib in Patients With MyelofibrosisCompletedNCT01445769Phase 2Results posted
• Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or LeukemiaCompletedNCT01445080Phase 1/2Results posted
• Cabozantinib in Women With Metastatic Hormone-Receptor-Positive Breast CancerCompletedNCT01441947Phase 2Results posted
• Dasatinib in Treating Patients With Chronic Lymphocytic LeukemiaCompletedNCT01441882Phase 2Results posted
• Lux-Breast 3; Afatinib Alone or in Combination With Vinorelbine in Patients With Human Epidermal Growth Factor Receptor 2 (HER2) Positive Breast Cancer Suffering From Brain MetastasesCompletedNCT01441596Phase 2Results posted
• Dovitinib for Imatinib/Sumitinib-failed Gastrointestinal Stromal Tumors (GIST): TKI258CompletedNCT01440959Phase 2Results posted
• Phase III Study of SAR302503 in Intermediate-2 and High Risk Patients With MyelofibrosisTerminatedNCT01437787Phase 3Results posted
• Pazopanib Hydrochloride in Treating Patients With Von Hippel-Lindau SyndromeCompletedNCT01436227Phase 2Results posted
• SB1518 for Patients With Myelodysplastic Syndrome (MDS)TerminatedNCT01436084Phase 2Results posted
• A Study of Axitinib in Advanced Carcinoid TumorsCompletedNCT01435122Phase 2Results posted
• Phase I-II Everolimus and Sorafenib in Recurrent High-Grade GliomasCompletedNCT01434602Phase 1/2Results posted
• A Study of E7050 in Combination With E7080 in Participants With Advanced Solid Tumors (Dose Escalation) and in Participants With Recurrent Glioblastoma or Unresectable Stage III or Stage IV Melanoma After Prior Systemic Therapy (Expansion Cohort and Phase 2)TerminatedNCT01433991Phase 1/2Results posted
• Ruxolitinib Phosphate to Treat Diffuse Large B-Cell or Peripheral T-Cell Non-Hodgkin Lymphoma After Stem Cell TransplantCompletedNCT01431209Phase 2Results posted
• Trial of Cabozantinib (XL184) in Castrate-Resistant Prostate Cancer Metastatic to BoneTerminatedNCT01428219Phase 2Results posted
• Investigation of Ritonavir Effects on Afatinib Exposure in Healthy SubjectsCompletedNCT01426958Phase 1Results posted
• Safety and Tolerability Study of Oral NS-018 in Patients With Primary Myelofibrosis (MF), Post-polycythemia Vera MF or Post-essential Thrombocythemia MFCompletedNCT01423851Phase 1/2Results posted
• Study of Ruxolitinib in Pancreatic Cancer PatientsCompletedNCT01423604Phase 2Results posted
• Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS)TerminatedNCT01418001Phase 1/2Results posted
• Safety and PK Study of BIBF 1120 in Japanese Patients With IPF: Follow up Study From 1199.31(NCT01136174)CompletedNCT01417156Phase 2Results posted
• Vandetanib in Preventing Head and Neck Cancer in Patients With Precancerous Head and Neck LesionsCompletedNCT01414426Phase 2Results posted
• AC220 for Children With Relapsed/Refractory ALL or AMLCompletedNCT01411267Phase 1Results posted
• Intercalating and Maintenance Use of Iressa Versus Chemotherapy in Selected Advanced Non Small Cell Lung CancerCompletedNCT01404260Phase 3Results posted
• Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform NeurofibromasTerminatedNCT01402817Phase 2Results posted
• A Relative Bioavailability and Food Effect Study of New FormulationsCompletedNCT01398475Phase 1Results posted
• Prevention of Recurrent Gastric or Duodenal Ulcers Caused by Low-dose Aspirin With Rabeprazole (E3810) Treatment (Planetarium Study)CompletedNCT01397448Phase 2/3Results posted
• Drug Interaction Study With Rifampicin and AfatinibCompletedNCT01396265Phase 1Results posted
• A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal TumorCompletedNCT01396148Phase 2Results posted
• Erlotinib Plus Tivantinib (ARQ 197) Versus Single Agent Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung CancerCompletedNCT01395758Phase 2Results posted
• Lapatinib With Carboplatin and Paclitaxel in Esophagus and Gastroesophageal Junction (GEJ)TerminatedNCT01395537Phase 1/2Results posted
• Dasatinib Added to Gemcitabine for Subjects With Locally-advanced Pancreatic CancerCompletedNCT01395017Phase 2Results posted
• Neo-adjuvant Therapy With Anastrozole Plus Pazopanib in Stage II and III ER+ Breast CancerTerminatedNCT01394211Phase 2Results posted
• The Safety And Efficacy Of Maintenance Therapy With CP-690,550CompletedNCT01393899Phase 2Results posted
• A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's DiseaseCompletedNCT01393626Phase 2Results posted
• Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)TerminatedNCT01392495Phase 3Results posted
• Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension ParticipantsCompletedNCT01392469Phase 3Results posted
• Asian Phase II Study of INC424 in Patients With Primary Myelofibrosis (MF), Post-PV MF or Post-ET MFCompletedNCT01392443Phase 2Results posted
• Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)CompletedNCT01392183Phase 2Results posted
• Sunitinib or Cediranib for Alveolar Soft Part SarcomaCompletedNCT01391962Phase 2Results posted
• Pazopanib in Imatinib Refractory or Intolerant Gastrointestinal Stromal Tumors (GIST)TerminatedNCT01391611Phase 2Results posted
• Axitinib Before Surgery in Treating Patients With High-Risk Prostate CancerCompletedNCT01385059Phase 2Results posted
• Entinostat And Imatinib Mesylate In Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Positive Acute Lymphoblastic LeukemiaTerminatedNCT01383447Phase 1/2Results posted
• Docetaxel and Lapatinib in Metastatic Transitional Cell Carcinoma in BladderTerminatedNCT01382706Phase 2Results posted
• BIBF 1120 for Recurrent High-Grade GliomasCompletedNCT01380782Phase 2Results posted
• A Phase II Study to Evaluate the Efficacy of TKI258 for the Treatment of Patients With FGFR2 Mutated or Wild-type Advanced and/or Metastatic Endometrial CancerCompletedNCT01379534Phase 2Results posted
• A Study of Tarceva (Erlotinib) in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (TRIGGER)CompletedNCT01378962Phase 2Results posted
• Ruxolitinib and Lenalidomide for Patients With MyelofibrosisCompletedNCT01375140Phase 2Results posted
• Vandetanib to Treat Advanced Kidney CancerTerminatedNCT01372813Phase 2Results posted
• A Study of Tarceva (Erlotinib) in Patients With Locally Advanced, Metastatic or Recurrent Non-Small Cell Cancer Who Present Epidermal Growth Factor Receptor MutationsCompletedNCT01372384Phase 2Results posted
• Bortezomib and Sorafenib Tosylate in Treating Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01371981Phase 3Results posted
• A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib ProtocolsTerminatedNCT01369433Not applicableResults posted
• Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGFTerminatedNCT01367275Phase 2Results posted

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